Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Giovanna M.E. Coura"'
Autor:
Renes R. Machado, Márcio M. Coelho, Ivo S.F. Melo, Marcela M.G.B. Dutra, Adriana M. Godin, Tamires C. Matsui, Wagner G. Canhestro, Ângelo de Fátima, Ana Mercy S. Brito, Ricardo José Alves, Giovanna M.E. Coura, Débora P. Araújo, Carla R.A. Batista
Publikováno v:
Pharmacological Reports. 71:1177-1183
Phthalimide analogues devoid of the glutarimide moiety exhibit multiple biological activities, thus making them candidates for the treatment of patients with different diseases, including those with inflammatory and painful disorders. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae93c2a1cd16bee68f042aa0837bd3e
https://doi.org/10.1016/j.pharep.2019.08.001
https://doi.org/10.1016/j.pharep.2019.08.001
Autor:
Ana Mercy S. Brito, Giovanna M.E. Coura, Raquel R. Menezes, Mauro M. Teixeira, Adriana M. Godin, Ivo S.F. Melo, Débora P. Araújo, Ângelo de Fátima, Márcio M. Coelho, Flávio A. Amaral, Renes R. Machado, Leandro F.S. Bastos
Publikováno v:
Pharmacological Reports. 69:691-695
Phthalimide analogs have been shown to exhibit anti-inflammatory, analgesic and immunomodulatory activities in different preclinical assays. This study aimed to investigate the potential role of 2-phthalimidethanol (PTD-OH) and 2-phthalimidethyl nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51af0ca37e14f726b50b8c93aebd13ba
https://doi.org/10.1016/j.pharep.2017.01.033
https://doi.org/10.1016/j.pharep.2017.01.033
Autor:
André Klein, Isabela Costa César, Giovanna M.E. Coura, Tamires C. Matsui, Danielle G. Souza, Lucas S. Ribeiro, Renes R. Machado, Adriana M. Godin, Paulo S. A. Augusto, Ivo S.F. Melo, Débora P. Araújo, Ângelo de Fátima, Márcio M. Coelho, Carla R.A. Batista
Publikováno v:
European Journal of Pharmacology. 769:306-312
Nicorandil is a drug characterized by the coupling of a nitric oxide (NO) donor to nicotinamide. We have previously demonstrated that nicotinamide exhibits activity in different models of pain and inflammation. Now, we investigated the effects induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b610bdaedf2bf8051d6ee0ef63a172b3
https://doi.org/10.1016/j.ejphar.2015.11.034
https://doi.org/10.1016/j.ejphar.2015.11.034
Autor:
Gerson Antônio Pianetti, Leandro F.S. Bastos, Mariana O. Almeida, Ivo S.F. Melo, Renes R. Machado, Carla R.A. Batista, Tamires C. Matsui, Márcio M. Coelho, Ricardo Martins Duarte Byrro, Isabela Costa César, Ângelo de Fátima, Giovanna M.E. Coura, Adriana M. Godin, Ana Mercy S. Brito, Débora P. Araújo, Raquel R. Menezes
Publikováno v:
European Journal of Pharmacology. 756:59-66
The activities of 2-phthalimidethyl nitrate (PTD-NO) and 2-phthalimidethanol (PTD-OH) were recently demonstrated in models of pain and inflammation. We expanded our investigation by evaluating their activities in models of nociceptive and inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3c7ee0301f9c4f9de891b817b6da71
https://doi.org/10.1016/j.ejphar.2015.02.052
https://doi.org/10.1016/j.ejphar.2015.02.052
Autor:
Ana Mercy S. Brito, Mauro M. Teixeira, Daniel Assis Santos, Márcio M. Coelho, Darly G. Soares, Renes R. Machado, Ângelo de Fátima, Julliana Ribeiro Alves Santos, Daiane Boff, Lucas S. Ribeiro, Leandro F.S. Bastos, Débora P. Araújo, Raquel R. Menezes, Flávio A. Amaral, Giovanna M.E. Coura, Ivo S.F. Melo, Adriana M. Godin
Publikováno v:
Pharmacology Biochemistry and Behavior. 122:291-298
The reintroduction of thalidomide in the pharmacotherapy greatly stimulated the interest in the synthesis and pharmacological evaluation of phthalimide analogs with new and improved activities and also greater safety. In the present study, we evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a2a793abe2b45818394e8bbfa3626e
https://doi.org/10.1016/j.pbb.2014.04.008
https://doi.org/10.1016/j.pbb.2014.04.008
Autor:
Renes R. Machado, Ivo S.F. Melo, Felipe F. Rodrigues, Tony P. Paulino, Márcio M. Coelho, Giovanna M.E. Coura, Caryne M. Bertollo, Adriana M. Godin, Milene Alvarenga Rachid, Raquel R. Menezes, Ana Mercy S. Brito
Publikováno v:
Pharmacological reports : PR. 69(5)
Background The effects induced by thiamine and riboflavin, isolated or in association with corticosteroids, in models of chronic inflammation are not known. Thus, we evaluated the effect induced by these B vitamins, isolated or in association with de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfec21a41167a1facd2380a01a6e9323
https://pubmed.ncbi.nlm.nih.gov/28958614
https://pubmed.ncbi.nlm.nih.gov/28958614
Autor:
Tony P. Paulino, Ivo S.F. Melo, Danielle G. Souza, Rafaela D. Nogueira, Giovanna M.E. Coura, Raquel R. Menezes, Márcio M. Coelho, Adriana M. Godin, Renes R. Machado, Darly G. Soares, Flávio A. Amaral, Ana Mercy S. Brito
Publikováno v:
Planta medica. 80(8-9)
Azadirachta indica (Meliaceae) extracts have been reported to exhibit anti-inflammatory and antinociceptive properties. However, the activities of azadirachtin, a limonoid and the major bioactive compound found in the extracts, have been poorly inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4e66685ec4e767072b579c2356b17c
https://pubmed.ncbi.nlm.nih.gov/24871207
https://pubmed.ncbi.nlm.nih.gov/24871207