Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Giovanna Farruggia"'
Autor:
Giovanna Farruggia, Lorenzo Anconelli, Lucrezia Galassi, Manuela Voltattorni, Martina Rossi, Pietro Lodeserto, Paolo Blasi, Isabella Orienti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Acute promyelocytic leukemia (APL) is characterized by rearrangements of the retinoic acid receptor, RARα, which makes all-trans retinoic acid (ATRA) highly effective in the treatment of this disease, inducing promyelocytes differentiation.
Externí odkaz:
https://doaj.org/article/4a10973b0c8341c9a383e4eb39c2a3e7
Autor:
Luca Pincigher, Francesca Valenti, Christian Bergamini, Cecilia Prata, Romana Fato, Riccardo Amorati, Zongxin Jin, Giovanna Farruggia, Diana Fiorentini, Natalia Calonghi, Chiara Zalambani
Publikováno v:
Molecules, Vol 28, Iss 18, p 6728 (2023)
γ-terpinene, α-terpinene, p-cymene, and myrcene are monoterpenes found in many essential oils extracted from a variety of plants and spices. Myrcene also occurs naturally in plants such as hops, cannabis, lemongrass, and verbena and is used as a fl
Externí odkaz:
https://doaj.org/article/2d216838d6564ac5af0037d20d3f067b
Autor:
Francesca Rossi, Giovanna Picone, Concettina Cappadone, Andrea Sorrentino, Marta Columbaro, Giovanna Farruggia, Emilio Catelli, Giorgia Sciutto, Silvia Prati, Robert Oliete, Alice Pasini, Eva Pereiro, Stefano Iotti, Emil Malucelli
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8559 (2023)
Osteosarcoma (OS) is the most common primary malignant bone tumor and its etiology has recently been associated with osteogenic differentiation dysfunctions. OS cells keep a capacity for uncontrolled proliferation showing a phenotype similar to undif
Externí odkaz:
https://doaj.org/article/63496f526c01401fb07e12df692bcd65
Autor:
Giacomo Drius, Silvia Bordoni, Carla Boga, Magda Monari, Jessica Fiori, Erika Esposito, Chiara Zalambani, Luca Pincigher, Giovanna Farruggia, Natalia Calonghi, Gabriele Micheletti
Publikováno v:
Molecules, Vol 28, Iss 10, p 4051 (2023)
Metallodrugs represent a combination of multifunctionalities that are present concomitantly and can act differently on diverse biotargets. Their efficacy is often related to the lipophilic features exhibited both by long carbo-chains and the phosphin
Externí odkaz:
https://doaj.org/article/a92648712d85438988fbc6d1ad34c71a
Autor:
Valentina Sallustio, Giovanna Farruggia, Massimiliano Pio di Cagno, Martina M. Tzanova, Joana Marto, Helena Ribeiro, Lidia Maria Goncalves, Manuela Mandrone, Ilaria Chiocchio, Teresa Cerchiara, Angela Abruzzo, Federica Bigucci, Barbara Luppi
Publikováno v:
Gels, Vol 9, Iss 5, p 362 (2023)
Rising environmental awareness drives green consumers to purchase sustainable cosmetics based on natural bioactive compounds. The aim of this study was to deliver Rosa canina L. extract as a botanical ingredient in an anti-aging gel using an eco-frie
Externí odkaz:
https://doaj.org/article/d1dcfc74a3b8447bb931730257fc8d4e
Autor:
Lucrezia Galassi, Martina Rossi, Pietro Lodeserto, Monia Lenzi, Francesca Borsetti, Manuela Voltattorni, Giovanna Farruggia, Paolo Blasi, Isabella Orienti
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 648 (2023)
Neuroblastoma cells highly express the disialoganglioside GD2, a tumor-associated carbohydrate antigen, which is also expressed in neurons, skin melanocytes, and peripheral nerve fibers. Immunotherapy with monoclonal anti-GD2 antibodies has a proven
Externí odkaz:
https://doaj.org/article/1a56ce1878e541dabea9dfab3d25bdc7
Autor:
Junwei Zhao, Jacopo Carbone, Giovanna Farruggia, Anna Janecka, Luca Gentilucci, Natalia Calonghi
Publikováno v:
Molecules, Vol 28, Iss 1, p 265 (2022)
Indoles constitute a large family of heterocyclic compounds widely occurring in nature which are present in a number of bioactive natural and synthetic compounds, including anticancer agents or atypical opioid agonists. As a result, exponential incre
Externí odkaz:
https://doaj.org/article/054dd5cb72444dc4980723e02a4b686f
Autor:
Gabriele Micheletti, Carla Boga, Chiara Zalambani, Giovanna Farruggia, Erika Esposito, Jessica Fiori, Nicola Rizzardi, Paola Taddei, Michele Di Foggia, Natalia Calonghi
Publikováno v:
Molecules, Vol 27, Iss 17, p 5645 (2022)
A series of naphthoquinones, namely, 1,4-naphthoquinone, menadione, plumbagin, juglone, naphthazarin, and lawsone, were reacted with N-acetyl-L-cysteine, and except for lawsone, which did not react, the related adducts were obtained. After the tuning
Externí odkaz:
https://doaj.org/article/221b4dcd36bd470995a395a41c166417
Autor:
Martina Rossi, Concettina Cappadone, Giovanna Picone, Alessandra Bisi, Giovanna Farruggia, Federica Belluti, Paolo Blasi, Silvia Gobbi, Emil Malucelli
Publikováno v:
Molecules, Vol 27, Iss 12, p 3751 (2022)
Osteosarcoma (OS) is a malignant disease characterized by poor prognosis due to a high incidence of metastasis and chemoresistance. Recently, Licochalcone A (Lic-A) has been reported as a promising agent against OS. Starting from chalcones selected f
Externí odkaz:
https://doaj.org/article/2608acf1e3a8415cb683cab22e131b75
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1215 (2022)
A new strategy to cause cell death in tumors might be the increase of intracellular polyamines at concentrations above their physiological values to trigger the production of oxidation metabolites at levels exceeding cell tolerance. To test this hypo
Externí odkaz:
https://doaj.org/article/077f33280adf40c38f26bcef3616643e