Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Giovanna Chiorino"'
Autor:
Anastasia Samarkina, Markus Kirolos Youssef, Paola Ostano, Soumitra Ghosh, Min Ma, Beatrice Tassone, Tatiana Proust, Giovanna Chiorino, Mitchell P. Levesque, Sandro Goruppi, Gian Paolo Dotto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Melanoma provides a primary benchmark for targeted drug therapy. Most melanomas with BRAFV600 mutations regress in response to BRAF/MEK inhibitors (BRAFi/MEKi). However, nearly all relapse within the first two years, and there is a connectio
Externí odkaz:
https://doaj.org/article/c3125598e94f431c92edea912b20ab71
Autor:
Giovanna Chiorino, Elisabetta Petracci, Emir Sehovic, Ilaria Gregnanin, Elisa Camussi, Maurizia Mello-Grand, Paola Ostano, Emilia Riggi, Viviana Vergini, Alessia Russo, Enrico Berrino, Andrea Ortale, Francesca Garena, Tiziana Venesio, Federica Gallo, Elisabetta Favettini, Alfonso Frigerio, Giuseppe Matullo, Nereo Segnan, Livia Giordano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Mammographic breast cancer screening is effective in reducing breast cancer mortality. Nevertheless, several limitations are known. Therefore, developing an alternative or complementary non-invasive tool capable of increasing the accuracy of
Externí odkaz:
https://doaj.org/article/044deb74a3a04e07afe4fafc799eea7d
Autor:
Chiara Arrigoni, Paola Ostano, Simone Bersini, Martina Crippa, Maria Vittoria Colombo, Mara Gilardi, Luigi Zagra, Maurizia Mello-Grand, Ilaria Gregnanin, Carmen Ghilardi, Maria Rosa Bani, Christian Candrian, Giovanna Chiorino, Matteo Moretti
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Angiogenic analysis and transcriptomics on bone and skeletal muscle endothelial cells from osteoarthritis patients reveal different inflammatory conditions have a different impact on these cell populations.
Externí odkaz:
https://doaj.org/article/92b46ef009ce4dd18c571b23a3075b35
Autor:
Laila Akhouayri, Paola Ostano, Maurizia Mello-Grand, Ilaria Gregnanin, Francesca Crivelli, Sara Laurora, Daniele Liscia, Francesco Leone, Angela Santoro, Antonino Mulè, Donatella Guarino, Claudia Maggiore, Angela Carlino, Stefano Magno, Maria Scatolini, Alba Di Leone, Riccardo Masetti, Giovanna Chiorino
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-17 (2022)
Abstract Background Triple-negative breast cancer (TNBC) is a very heterogeneous disease. Several gene expression and mutation profiling approaches were used to classify it, and all converged to the identification of distinct molecular subtypes, with
Externí odkaz:
https://doaj.org/article/fce1364bc95e48129fe63fabaf1063c5
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-23 (2022)
Abstract Background Breast cancer (BC) is the most frequently diagnosed cancer among women. Numerous studies explored cell-free circulating microRNAs as diagnostic biomarkers of BC. As inconsistent and rarely intersecting microRNA panels have been re
Externí odkaz:
https://doaj.org/article/be35f7bd16ad4f459e47be039e4e485f
Autor:
Marita Zoma, Laura Curti, Dheeraj Shinde, Domenico Albino, Abhishek Mitra, Jacopo Sgrignani, Sarah N. Mapelli, Giada Sandrini, Gianluca Civenni, Jessica Merulla, Giovanna Chiorino, Paolo Kunderfranco, Alessia Cacciatore, Aleksandra Kokanovic, Andrea Rinaldi, Andrea Cavalli, Carlo V. Catapano, Giuseppina M. Carbone
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Although the TMPRSS2-ERG gene fusion is the most common alteration in human prostate cancer, its involvement in disease progression remains unclear. Here, the authors demonstrate that ERG is methylated by Enhancer of zest homolog 2 leading to enhance
Externí odkaz:
https://doaj.org/article/e634d5688e6b4dc7aff08bbd1aa3f1c9
Autor:
Xiaoying Xu, Beatrice Tassone, Paola Ostano, Atul Katarkar, Tatiana Proust, Jean‐Marc Joseph, Chiara Riganti, Giovanna Chiorino, Zoltan Kutalik, Karine Lefort, Gian Paolo Dotto
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 7, Pp 1-21 (2021)
Abstract Human populations of Black African ancestry have a relatively high risk of aggressive cancer types, including keratinocyte‐derived squamous cell carcinomas (SCCs). We show that primary keratinocytes (HKCs) from Black African (Black) versus
Externí odkaz:
https://doaj.org/article/bbde4af1e1d84b45a602c7eeb0607f71
Autor:
Stefania Nobili, Antonella Mannini, Astrid Parenti, Chiara Raggi, Andrea Lapucci, Giovanna Chiorino, Sara Paccosi, Paola Di Gennaro, Vania Vezzosi, Paolo Romagnoli, Tommaso Susini, Marcella Coronnello
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Invasive ductal carcinoma (IDC) constitutes the most frequent malignant cancer endangering women’s health. In this study, a new spontaneously immortalized breast cancer cell line, DHSF-BR16 cells, was isolated from the primary IDC of a 74-
Externí odkaz:
https://doaj.org/article/343a8a71c6f64f52a75d7ed4738556e0
Autor:
Elena Berrone, Giovanna Chiorino, Francesca Guana, Valerio Benedetti, Claudia Palmitessa, Marina Gallo, Andrea Calvo, Federico Casale, Umberto Manera, Alessandra Favole, Paola Crociara, Camilla Testori, Valerio Carta, Carlotta Tessarolo, Antonio D’Angelo, Giovanni De Marco, Maria Caramelli, Adriano Chiò, Cristina Casalone, Cristiano Corona
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1899 (2023)
Amyotrophic lateral sclerosis (ALS) is a complex disease characterized by the interplay of genetic and environmental factors for which, despite decades of intense research, diagnosis remains rather delayed, and most therapeutic options fail. Therefor
Externí odkaz:
https://doaj.org/article/89fef6c8147e4d41801be6301596b98b
Autor:
Maurizia Mello-Grand, Antonino Bruno, Lidia Sacchetto, Simone Cristoni, Ilaria Gregnanin, Alessandro Dematteis, Andrea Zitella, Paolo Gontero, Caterina Peraldo-Neia, Riccardo Ricotta, Douglas M. Noonan, Adriana Albini, Giovanna Chiorino
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Reliable liquid biopsy-based tools able to accurately discriminate prostate cancer (PCa) from benign prostatic hyperplasia (BPH), when PSA is within the “gray zone” (PSA 4–10), are still urgent. We analyzed plasma samples from a cohort of 102 c
Externí odkaz:
https://doaj.org/article/62a2a94d6e1142f6afb3f836b01fc657