Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giovanna Carrá"'
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract The dysregulation of miRNAs in lung cancer has been extensively documented, with specific miRNAs acting as both tumor suppressors and oncogenes, depending on their target genes. Recent research has unveiled the regulatory roles of miRNAs in
Externí odkaz:
https://doaj.org/article/e5cf66b66418470c8941cb22f18f8c0e
Autor:
Carla Riera-Domingo, Eduarda Leite-Gomes, Iris Charatsidou, Peihua Zhao, Giovanna Carrá, Federica Cappellesso, Larissa Mourao, Maxim De Schepper, Dana Liu, Jens Serneels, Mohamad-Gabriel Alameh, Vladimir V. Shuvaev, Tatjana Geukens, Edoardo Isnaldi, Hans Prenen, Drew Weissman, Vladimir R. Muzykantov, Stefaan Soenen, Christine Desmedt, Colinda L. G. J. Scheele, Anna Sablina, Mario Di Matteo, Rosa Martín-Pérez, Massimiliano Mazzone
Publikováno v:
Science Advances
Endothelial cells (ECs) grant access of disseminated cancer cells to distant organs. However, the molecular players regulating the activation of quiescent ECs at the premetastatic niche (PMN) remain elusive. Here, we find that ECs at the PMN coexpres
Autor:
Pietro Poggio, Stefania Rocca, Federica Fusella, Roberta Ferretti, Ugo Ala, Flora D’Anna, Emilia Giugliano, Cristina Panuzzo, Diletta Fontana, Valeria Palumbo, Giovanna Carrà, Daniela Taverna, Carlo Gambacorti-Passerini, Giuseppe Saglio, Carmen Fava, Rocco Piazza, Alessandro Morotti, Francesca Orso, Mara Brancaccio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Morgana is a ubiquitous HSP90 co-chaperone protein coded by the CHORDC1 gene. Morgana heterozygous mice develop with age a myeloid malignancy resembling human atypical myeloid leukemia (aCML), now renamed MDS/MPN with neutrophilia. Patients
Externí odkaz:
https://doaj.org/article/6c827363c8c04882b2a5e5aa1fda4491
Autor:
Giovanna Carrà, Emilia Giugliano, Sofia Camerlo, Giorgio Rosati, Enrica Branca, Beatrice Maffeo, Isabella Russo, Rocco Piazza, Daniela Cilloni, Alessandro Morotti
Publikováno v:
Haematologica, Vol 108, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/99cfd68748cf4b2491bb2203a464b257
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
NF-κB is diffusely recognized as a transcriptional factor able to modulate the expression of various genes involved in a broad spectrum of cellular functions, including proliferation, survival and migration. NF-κB is, however, also acting outside t
Externí odkaz:
https://doaj.org/article/919f4d23b2a24632af6285641e7223d1
Autor:
Giovanna Carrà, Giuseppe Ermondi, Chiara Riganti, Luisella Righi, Giulia Caron, Alessio Menga, Enrica Capelletto, Beatrice Maffeo, Marcello Francesco Lingua, Federica Fusella, Marco Volante, Riccardo Taulli, Angelo Guerrasio, Silvia Novello, Mara Brancaccio, Rocco Piazza, Alessandro Morotti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Oxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the major cause of oxidative stress. Cell fate is known to be intricately li
Externí odkaz:
https://doaj.org/article/e99368fd3c9f4f83b919dcfdbb330f8a
Autor:
Sofia Camerlo, Jacopo Ligato, Giorgio Rosati, Giovanna Carrà, Isabella Russo, Marco De Gobbi, Alessandro Morotti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2262 (2023)
Splanchnic vein thrombosis is a rare but potentially life-threatening manifestation of venous thromboembolism, with challenging implications both at the pathological and therapeutic level. It is frequently associated with liver cirrhosis, but it coul
Externí odkaz:
https://doaj.org/article/59db6324bcd144a7bcf6b71f831767c7
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Atypical Chronic Myeloid Leukemia (aCML) is a myeloproliferative neoplasm characterized by neutrophilic leukocytosis and dysgranulopoiesis. From a genetic point of view, aCML shows a heterogeneous mutational landscape with mutations affectin
Externí odkaz:
https://doaj.org/article/40065103f2c14348b405ee7bcbed3812
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 168 (2021)
For many years in the field of onco-hematology much attention has been given to mutations in protein-coding genes or to genetic alterations, including large chromosomal losses or rearrangements. Despite this, biological and clinical needs in this sec
Externí odkaz:
https://doaj.org/article/250897d1284b4bebaa4cd31b93111dd6
Autor:
Sara Petrillo, Giovanna Carrà, Paolo Bottino, Elisa Zanotto, Maria Chiara De Santis, Jean Piero Margaria, Alessandro Giorgio, Giorgia Mandili, Miriam Martini, Rossana Cavallo, Davide Barberio, Fiorella Altruda
Publikováno v:
Microorganisms, Vol 8, Iss 7, p 1064 (2020)
Rapid and sensitive screening of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to limit the spread of the global pandemic we are facing. Quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) is c
Externí odkaz:
https://doaj.org/article/db8596ce08954f349597c12b53ee6f54