Výsledky vyhledávání - "Giovanna Buttice"

Human Chromosomal Localization, Tissue/Tumor Expression, and Regulatory Function of the ets Family Gene EHF

Autor: Greg P. Coffey, Giovanna Buttice, Laurie A. Kleinbaum, Catherine Duggan, Frank H. Burton, Elisabeth Ferreira

Publikováno v: Biochemical and Biophysical Research Communications. 264:119-126

Ets factors are members of an ancient multigene family of transcription factors including oncoproteins and possibly tumor suppressors. We previously characterized a novel divergent ets gene, Ehf (ets homologous factor) in mice. Here we report the cDN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6290fe8b004606874941ccd82f97d5
https://doi.org/10.1006/bbrc.1999.1493

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The Ets Transcription Factors Interact with Each Other and with the c-Fos/c-Jun Complex via Distinct Protein Domains in a DNA-dependent and -independent Manner

Autor: Elisabeth Ferreira, Giovanna Buttice, Dominique Stehelin, Jean Philippe Basuyaux

Publikováno v: Journal of Biological Chemistry. 272:26188-26195

The transcription factors Fos, Jun, and Ets regulate the expression of human stromelysin-1 and collagenase-1 genes. Recently, we found that ERG, an Ets family member, activates collagenase-1 gene but not stromelysin-1 by physically interacting with c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b5adc3876a7f454e0f977dc0f18f44
https://doi.org/10.1074/jbc.272.42.26188

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The AP-1 site Is required for basal expression but is not necessary for TPA-response of the human stromelysin gene

Autor: S Quinones, Giovanna Buttice, Markku Kurkinen

Publikováno v: Nucleic Acids Research. 19:3723-3731

We have studied the activity of the AP-1 site, a target for the Fos and Jun family of transcription factors, in the context of the human stromelysin promoter (-1303 to +4). In transiently transfected human HepG2, HeLa and fibroblast cell cultures, po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0ae36c0bffbc41d252d8b5c7f92fa5
https://doi.org/10.1093/nar/19.13.3723

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p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter

Autor: Sigmund A. Weitzman, Bayar Thimmapaya, Kumaravel Somasundaram, Giovanna Buttice, Elisabeth Ferreira, Catherine Duggan, Gopalswamy Jayaraman, Ravi Dhar, Justin Williams, Markku Kurkinen, Rampalli Srinivas, Craig A. Hauser, Sathyamangalam Swaminathan

Publikováno v: The Journal of biological chemistry. 274(24)

In this paper we show that transcription factors Ets-1 and Ets-2 recruit transcription adapter proteins p300 and CBP (cAMP-responsive element-binding protein) during the transcriptional activation of the human stromelysin promoter, which contains pal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103bae14a96a9d52359f99eae61113a6
https://pubmed.ncbi.nlm.nih.gov/10358095

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Promoter elements in the transcriptional activation of the human stromelysin-1 gene by the inflammatory cytokine, interleukin 1

Autor: Giovanna Buttice, Markku Kurkinen, S Quinones

Publikováno v: The Biochemical journal. 302

Stromelysin-1, a tissue-remodelling metalloproteinase synthesized by fibroblasts, has proteolytic activity against a variety of extracellular matrix components. Stromelysin-1 gene transcription is induced by the inflammatory cytokine interleukin (IL)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e1e3bec2a70fd7bb1bd75d984c14f0
https://pubmed.ncbi.nlm.nih.gov/8092999

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Evolution of collagen IV genes from a 54-base pair exon: a role for introns in gene evolution

Autor: Jeanine D'Armiento, Markku Kurkinen, Gabriel Vogeli, Giovanna Buttice, Paul S. Kaytes

Publikováno v: Journal of molecular evolution. 30(6)

The exon structure of the collagen IV gene provides a striking example for collagen evolution and the role of introns in gene evolution. Collagen IV, a major component of basement membranes, differs from the fibrillar collagens in that it contains nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46cb83c7987ad8d1941758a09ec70a3
https://pubmed.ncbi.nlm.nih.gov/2115927

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Mini-transfections on 96-well microtiter plates

Autor: Giovanna Buttice, Markku Kurkinen

Publikováno v: Nucleic acids research. 18(10)

Transient transfection is one of the most commonly used techniques to study gene regulation. Different reporter genes have been used to quantitate the promoter activity. CAT (chloramphenicol acetyltransferase) is the reporter gene most often used in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3691b328ae7f748a117c85ae8c9e124c
https://pubmed.ncbi.nlm.nih.gov/2135391

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Isolation of a putative collagen-like gene from the sea urchin Paracentrotus lividus

Autor: Biagio Saitta, Giovanna Buttice, Roberto Gambino

Publikováno v: Biochemical and biophysical research communications. 158(3)

Using a Caenorhabditis elegans collagen probe we have isolated a 17.6 kb clone from a Paracentrotus lividus genomic library. Sequencing of nearly 2.6 kb identified five open reading frames flanked at both sides by splice site consensus sequences and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a4f0ae9ebae35a5c168bd791d19473
https://pubmed.ncbi.nlm.nih.gov/2537631

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