Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Giovanna Bosshard"'
Autor:
Yuan-Chen Tsai, Mohammad Hleihil, Kanako Otomo, Andrin Abegg, Anna Cavaccini, Patrizia Panzanelli, Teresa Cramer, Kim David Ferrari, Matthew J. P. Barrett, Giovanna Bosshard, Theofanis Karayannis, Bruno Weber, Shiva K. Tyagarajan, Jillian L. Stobart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Gephyrin is the main scaffolding protein at inhibitory postsynaptic sites, and its clusters are the signaling hubs where several molecular pathways converge. Post-translational modifications (PTMs) of gephyrin alter GABAA receptor clustering
Externí odkaz:
https://doaj.org/article/61f06bd1f1de40d1b7c391b161388674
Autor:
Claire de Groot, Amalia Floriou-Servou, Yuan-Chen Tsai, Simon Früh, Manuela Kohler, Georgia Parkin, Cornelia Schwerdel, Giovanna Bosshard, Kai Kaila, Jean-Marc Fritschy, Shiva K Tyagarajan
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007073 (2017)
In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic syna
Externí odkaz:
https://doaj.org/article/7cb2b632fcce41a0b646288801f9b475
Autor:
Shiva K. Tyagarajan, Giovanna Bosshard, Benjamin F. N. Campbell, Jean-Marc Fritschy, Simon Früh
Publikováno v:
Journal of Neurochemistry. 147:477-494
In dissociated neuronal cultures the absence of spatial and temporal cues causes the emergence of mismatched synapses, where post-synaptic proteins of GABAergic synapses are in part apposed to glutamatergic pre-synaptic terminals and vice versa. This
Autor:
Yuan-Chen Tsai, Mohammad Hleihil, Kanako Otomo, Andrin Abegg, Anna Cavaccini, Patrizia Panzanelli, Teresa Cramer, Kim David Ferrari, Matthew J.P. Barrett, Giovanna Bosshard, Theofanis Karayannis, Bruno Weber, Jillian L. Stobart, Shiva K. Tyagarajan
A diverse set of GABAA receptors (GABAARs) enable synaptic plasticity adaptations at inhibitory postsynaptic sites in collaboration with the scaffolding protein gephyrin. Early studies helped to identify distinctions between GABAAR subtypes allocated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fd2aff0c65ae3671aacdabde34ecc4
https://doi.org/10.1101/2020.11.25.397877
https://doi.org/10.1101/2020.11.25.397877
Autor:
Shiva K. Tyagarajan, Matthew J.P. Barrett, Yuan-Chen Tsai, Giovanna Bosshard, Teresa Cramer, Jillian L. Stobart, Mohammad Hleihil, Kim David Ferrari, Bruno Weber
Publikováno v:
SSRN Electronic Journal.
A diverse set of GABAA receptors (GABAARs) enable synaptic plasticity adaptations at inhibitory postsynaptic sites in collaboration with the scaffolding protein gephyrin. Early studies helped to identify distinctions between GABAAR subsets allocated
Autor:
Amalia Floriou-Servou, Manuela Kohler, Giovanna Bosshard, Georgia M. Parkin, Claire de Groot, Simon Frueh, Shiva K. Tyagarajan, Kai Kaila, Yuan-Chen Tsai, Cornelia Schwerdel, Jean-Marc Fritschy
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007073 (2017)
PLoS Genetics
PLoS Genetics
In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f078612a7aeef479b62806ac5e374683
https://doi.org/10.1101/197905
https://doi.org/10.1101/197905
Autor:
Giovanna Bosshard, Steven J Moss, Christine Bole-Feysot, Jean-Marc Fritschy, Karine Siquier-Pernet, Patrick Nitschké, Olivier Alibeu, Ann-Kristina Fritz, Dennis Mircsof, David P. Wolfer, Florence Crestani, Markus Rudin, Steven A. Brown, Nathalie Boddaert, Rochelle M. Hines, Arnold Munnich, Jeanne Amiel, Petra Seebeck, Matej Žnidarič, Christina Koester, Nicolas Cagnard, Ludmila Gaspar, Maéva Langouët, Shiva K. Tyagarajan, Laurence Colleaux, Aileen Schröter, Marlène Rio, Sébastien Moutton, Katrina Prescott
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2015, 18 (12), pp.1731-1736. ⟨10.1038/nn.4169⟩
Nature Neuroscience, Nature Publishing Group, 2015, 18 (12), pp.1731-1736. ⟨10.1038/nn.4169⟩
The NONO protein has been characterized as an important transcriptional regulator in diverse cellular contexts. Here we show that loss of NONO function is a likely cause of human intellectual disability and that NONO-deficient mice have cognitive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4021ff7fe23936013a6aae386fd0646
https://hal.archives-ouvertes.fr/hal-02088168
https://hal.archives-ouvertes.fr/hal-02088168
Autor:
Marek Cebecauer, Petra Baumgaertner, Immanuel F. Luescher, Philippe Guillaume, Georgi S. Angelov, Danijel Dojcinovic, Giovanna Bosshard
Publikováno v:
ResearcherID
Soluble MHC-peptide (pMHC) complexes induce intracellular calcium mobilization, diverse phosphorylation events, and death of CD8+ CTL, given that they are at least dimeric and coengage CD8. By testing dimeric, tetrameric, and octameric pMHC complexes
Autor:
Zsuzsanna Varga, Doris Kradolfer, Christian Öhlschlegel, Holger Moch, Raymond R. Tubbs, Aurelia Noske, Giovanna Bosshard, Wolfram Jochum, Zhen Wang, Yang Sun
Co-amplification of the centromere on chromosome 17 (CEP17) and HER2 can occur in breast cancer. Such aberrant patterns (clusters) on CEP17 can be misleading to calculate the HER2/CEP17 ratio, and thus underreporting of HER2 amplification. We identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c4c1011591176c729637eeec1de32f
Autor:
Giovanna Bosshard, Philippe Guillaume, Silke Mark, Daniel F. Legler, Horst Vogel, Immanuel F. Luescher, Georgi S. Angelov, Danijel Dojcinovic, Alexandre Johannsen, Jean-Manuel Segura
CD8+ cytotoxic T lymphocytes (CTL) can recognize and kill target cells expressing only a few cognate major histocompatibility complex (MHC) I-peptide complexes. This high sensitivity requires efficient scanning of a vast number of highly diverse MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f201c4d708a9f3b5406bfa03404110a
https://infoscience.epfl.ch/record/148629
https://infoscience.epfl.ch/record/148629