Cavitation as a zero-waste circular economy process to convert citrus processing waste into biopolymers in high demand

Autor: Rosaria Ciriminna, Giuseppe Angellotti, Giovanna Li Petri, Francesco Meneguzzo, Cristina Riccucci, Gabriella Di Carlo, Mario Pagliaro

Publikováno v: Journal of Bioresources and Bioproducts, Vol 9, Iss 4, Pp 486-494 (2024)

Cavitation in water only, no matter whether hydrodynamic or acoustic, is a zero-waste circular economy process to convert industrial citrus processing waste into high-performance polysaccharides in high demand in a single-step at room temperature and

Externí odkaz: https://doaj.org/article/4d0c03950a864b61a28e26c1eaf97d62

Reproducibility in chemistry research

Autor: Rosaria Ciriminna, Giuseppe Angellotti, Giovanna Li Petri, Mario Pagliaro

Publikováno v: Heliyon, Vol 10, Iss 14, Pp e33658- (2024)

Chemistry is a reproducible science whose pillars - synthesis and analysis - actually comprise a huge collection of highly reproducible experimental methods to synthesize and analyze substances. The historical development of chemistry, furthermore, s

Externí odkaz: https://doaj.org/article/daf5415cda89408da8f54b8e9532ddc0

New Synthetic Nitro-Pyrrolomycins as Promising Antibacterial and Anticancer Agents

Autor: Maria Valeria Raimondi, Alessandro Presentato, Giovanna Li Petri, Miriam Buttacavoli, Agnese Ribaudo, Viviana De Caro, Rosa Alduina, Patrizia Cancemi

Publikováno v: Antibiotics, Vol 9, Iss 6, p 292 (2020)

Pyrrolomycins (PMs) are polyhalogenated antibiotics known as powerful biologically active compounds, yet featuring high cytotoxicity. The present study reports the antibacterial and antitumoral properties of new chemically synthesized PMs, where the

Externí odkaz: https://doaj.org/article/400fcce9815849ee9240cedbe6953b63

New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma

Autor: Silvia Zoppi, Btissame El Hassouni, Godefridus J. Peters, Girolamo Cirrincione, Elisa Giovannetti, Andrea Cavazzoni, Daniela Carbone, Camilla Pecoraro, Giovanna Li Petri, Stella Cascioferro, Patrizia Diana, Ornella Randazzo, Barbara Parrino, Nadia Zaffaroni

Publikováno v: Anticancer Research, 40(9), 4913-4919. International Institute of Anticancer Research
Petri, G L I, Pecoraro, C, Randazzo, O, Zoppi, S, Cascioferro, S M, Parrino, B, Carbone, D, Hassouni, B E L, Cavazzoni, A, Zaffaroni, N, Cirrincione, G, Diana, P, Peters, G J & Giovannetti, E 2020, ' New imidazo[2,1-b][1,3,4]thiadiazole aerivatives anhibit FAK phosphorylation and potentiate the antiproliferative effects of gemcitabine through modulation of the human equilibrative nucleoside transporter-1 in peritoneal mesothelioma ', Anticancer Research, vol. 40, no. 9, pp. 4913-4919 . https://doi.org/10.21873/anticanres.14494

Background/aim A new class of imidazo[2,1-b][1,3,4]thiadiazole compounds have recently been evaluated as inhibitors of phosphorylation of focal adhesion kinase (FAK) in pancreatic cancer. FAK is overexpressed in mesothelioma and has recently emerged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01c41eda81084ed3059a1fcd5519282
https://doi.org/10.21873/anticanres.14494

Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors

Autor: Giovanna Li Petri, Simona Di Martino, Maria De Rosa

Publikováno v: Journal of medicinal chemistry. 65(11)

The use of peptides as therapeutics has often been associated with several drawbacks such as poor absorption, low stability to proteolytic digestion, and fast clearance. Peptidomimetics are developed by modifications of native peptides with the aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad6276f3a62468b5b3c3eda2ae6c76b
https://pubmed.ncbi.nlm.nih.gov/35604326