Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Giovanna, Leoni"'
Autor:
Giovanna Leoni, Oliver Soehnlein
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiovascular diseases, including myocardial infarction and its complications such as heart failure, are the leading cause of death worldwide. To date, basic and translational research becomes necessary to unravel the mechanisms of cardiac repair po
Externí odkaz:
https://doaj.org/article/7232d4310ece446099416fe321d1b859
Autor:
S. J. Getting, M. Kaneva, Y. Bhadresa, D. Renshaw, Giovanna Leoni, H. B. Patel, M. J. P. Kerrigan, I. C. Locke
Publikováno v:
The Scientific World Journal, Vol 9, Pp 1394-1414 (2009)
Arthritic pathologies are a major cause of morbidity within the western world, with rheumatoid arthritis affecting approximately 1% of adults. This review highlights the therapeutic potential of naturally occurring hormones and their peptides, in bot
Externí odkaz:
https://doaj.org/article/9746ce83716d408cae8ad4997216174a
Autor:
Sabine Steffens, Johan Duchene, Katrin Nitz, Christian Weber, Maximilian J. Schloss, Bruno Luckow, Michael Hilby, Thorsten Kessler, Michael Horckmans, Giovanna Leoni, Oliver Soehnlein, Raquel Guillamat Prats, Wenyan He, Bartolo Ferraro
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 37(9), 1640-1645. LIPPINCOTT WILLIAMS & WILKINS
Objective— Circadian regulation of neutrophil homeostasis affects myocardial infarction (MI) healing. It is unknown whether diurnal variations of monocyte counts exist in the heart and whether this affects their cardiac infiltration in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7107f943497523b060404e36be1fb195
https://doi.org/10.1161/atvbaha.117.309259
https://doi.org/10.1161/atvbaha.117.309259
Autor:
Priya H. Dedhia, Mingli Feng, Roland Hilgarth, Hikaru Nishio, Charles A. Parkos, Timothy L. Denning, Giovanna Leoni, Monique N. O’Leary, Dorothee Siuda, Asma Nusrat, Holly C. Williams, Jennifer C. Brazil, Veronica Azcutia, Miguel Quiros, Vicky Garcia-Hernandez, Philipp Neumann, Gabriela Bernal, Christian Gerner-Smidt, Jason R. Spence
Publikováno v:
Journal of Clinical Investigation. 127:3510-3520
In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated by dynamic crosstalk between immune cells and the epithelium; however, the mechanisms involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61902adb6026c8a9890e3aa85e2841d5
https://doi.org/10.1172/jci90229
https://doi.org/10.1172/jci90229
Autor:
Joana R. Viola, Bartolo Ferraro, Dario Bongiovanni, Chris P. M. Reutelingsperger, Renske J. de Jong, Almudena Ortega-Gomez, Hendrik B. Sager, Yvonne Döring, Michele D'Amico, Sanne L. Maas, Tanja Zeller, Nicole Paulin, Michael Hristov, Christian Kupatt, Rabea Hinkel, Thorsten Kessler, Tarik Bozoglu, Giovanna Leoni, Steffen Ormanns, Oliver Soehnlein, Matthias Nahrendorf
Publikováno v:
Journal of the American College of Cardiology
Journal of the American College of Cardiology, 73(23), 2990-3002. Elsevier Science
Journal of the American College of Cardiology, 73(23), 2990-3002. Elsevier Science
BACKGROUND Heart failure following myocardial infarction (MI) remains one of the major causes of death worldwide, and its treatment is a crucial challenge of cardiovascular medicine. An attractive therapeutic strategy is to stimulate endogenous mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcb235a9ebb77e885ee2754308460fc
Publikováno v:
Cell Adhesion & Migration. 11:261-274
The inflammatory response protects the human body against infection and injury. However, uncontrolled and unresolved inflammation can lead to tissue damage and chronic inflammatory diseases. Therefore, active resolution of inflammation is essential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf4d3f0d5121f0291889da1661bf347
https://doi.org/10.1080/19336918.2016.1259059
https://doi.org/10.1080/19336918.2016.1259059
Autor:
Asma Nusrat, Giovanna Leoni
Publikováno v:
Biological Chemistry. 397:971-979
Epithelial barriers play an important role in regulating mucosal homeostasis. Upon injury, the epithelium and immune cells orchestrate repair mechanisms that re-establish homeostasis. This process is highly regulated by protein and lipid mediators su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45d1431c666d4dcfd61bc2a7f5af8c1
https://doi.org/10.1515/hsz-2016-0180
https://doi.org/10.1515/hsz-2016-0180
Autor:
Maximilian J, Schloss, Michael, Hilby, Katrin, Nitz, Raquel, Guillamat Prats, Bartolo, Ferraro, Giovanna, Leoni, Oliver, Soehnlein, Thorsten, Kessler, Wenyan, He, Bruno, Luckow, Michael, Horckmans, Christian, Weber, Johan, Duchene, Sabine, Steffens
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 37(9)
Circadian regulation of neutrophil homeostasis affects myocardial infarction (MI) healing. It is unknown whether diurnal variations of monocyte counts exist in the heart and whether this affects their cardiac infiltration in response to MI.Murine blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb6ece75324611c9bbcef317da255516
https://pubmed.ncbi.nlm.nih.gov/28663258
https://pubmed.ncbi.nlm.nih.gov/28663258
Autor:
Charles A. Parkos, Rakieb Andargachew, Ronen Sumagin, Philipp Neumann, Jennifer C. Brazil, Oscar Medina-Contreras, Dominique A. Weber, Timothy L. Denning, Asma Nusrat, Giovanna Leoni, Ingrid C. McCall
Publikováno v:
Mucosal immunology
Neutrophil transepithelial migration (TEM) during acute inflammation is associated with mucosal injury. Using models of acute mucosal injury in vitro and in vivo, we describe a new mechanism by which neutrophils infiltrating the intestinal mucosa dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944303859b27997c83b395f235ee4ea2
https://doi.org/10.1038/mi.2014.12
https://doi.org/10.1038/mi.2014.12
Autor:
Asma Nusrat, Rheinallt M. Jones, Huixia Wu, Andrew S. Neish, Ashfaqul Alam, Christy Wentworth, Courtney S. Ardita, Jaclyn Kwal, Giovanna Leoni, J D Lambeth, Phillip A. Swanson
Publikováno v:
Mucosal immunology
The mammalian gut microbiota is essential for normal intestinal development, renewal, and repair. Injury to the intestinal mucosa can occur with infection, surgical trauma, and in idiopathic inflammatory bowel disease. Repair of mucosal injury, terme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb6dfb372a513f2ba58926fc9e48c28
https://doi.org/10.1038/mi.2013.84
https://doi.org/10.1038/mi.2013.84