Výsledky vyhledávání - "Giovanna, Baccante"

Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study

Autor: Scott Gleim, John Hwa, Kent Sierra, Min Ding, Ryan J. Horvath, Stefania Tacconelli, Valeria Moretta, Maria Domenica Guglielmi, Luigia Di Francesco, Jeremiah Stitham, Giovanna Baccante, Paola Patrignani, Karen Douville, Concetta Di Febbo, Marta L. Capone, Ettore Porreca

Publikováno v: Pharmacogenetics and Genomics. 18:611-620

Objective and methods The role of prostacyclin in the development of venous thrombosis and vascular dysfunction in humans is unclear. In patients with deep vein thrombosis (DVT, n=34) and controls (matched for age, sex, indexes of systemic inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43d25e7ace8b5567144a9e9f75aaeba
https://doi.org/10.1097/fpc.0b013e328301a774

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Pravastatin up-regulates transforming growth factor-β1 in THP-1 human macrophages: effect on scavenger receptor class A expression

Autor: Giovanna Baccante, Franco Cuccurullo, Ettore Porreca, Alessandro Piccirelli, Gabriella Mincione, Maria Carmela Di Marcantonio

Publikováno v: Biochemical and Biophysical Research Communications. 314:704-710

Statins have been shown to interact with several monocyte/macrophage functions. We tested the effect of pravastatin on transforming growth factor-beta1 (TGF-beta1) production and its possible involvement in scavenger receptors class A (SRA) expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632a040148a88a796973cac569bd5446
https://doi.org/10.1016/j.bbrc.2003.12.150

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Identification of Three Genetic Risk Factors for Venous Thrombosis Using a Multiplex Allele-Specific PCR Assay: Comparison of Conventional and New Alternative Methods for the Preparation of DNA from Clinical Samples

Autor: Carmine Di Ilio, Antonio Angelini, Giovanna Baccante, Ettore Porreca, Franco Cuccurullo, Marcello Di Nisio, Concetta Di Febbo

Publikováno v: Journal of Thrombosis and Thrombolysis. 16:189-193

The demand for thrombophilia testing at the molecular level is increasing and with it the need for a simple and rapid and cost-saving procedure for the preparation of genomic DNA from whole blood samples. The aim of this paper is to compare the effic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aef15422b7152e155b10c284bbbcbdd
https://doi.org/10.1023/b:thro.0000024057.37588.2a

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Transforming growth factor-β1 levels in hypertensive patients: association with body mass index and leptin1

Autor: Antonio Angelini, Franco Cuccurullo, Francesca Febo, Augusto Di Castelnuovo, Ettore Porreca, Ester Vitacolonna, Giovanna Baccante, Marcello Di Nisio, Concetta Di Febbo

Publikováno v: American Journal of Hypertension. 15:759-765

Background Transforming growth factor-β 1 (TGF-β 1 ) has been demonstrated to be overexpressed in hypertension. Leptin, an adipocyte product, has been shown to play a role in obesity-related hypertension and in vitro studies demonstrated a biologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5201eecfbe52dfdfa795c7bc9fd380c2
https://doi.org/10.1016/s0895-7061(02)02978-3

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Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients

Autor: Rita Sergi, Luciano Orsini, Marcella Reale, Riccardo Bertini, Gianfranco Caselli, Franco Cuccurullo, Giovanna Baccante, Ettore Porreca, Concetta Di Febbo

Publikováno v: Atherosclerosis. 146:345-350

Interleukin-8 is a cytokine produced by mononuclear cells that is involved in polymorphonuclear neutrophil leukocyte (PMN) recruitment and activation. Several studies have previously demonstrated a leukocyte activation during hypercholesterolemia and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83dce6556e6d6cfba82e4dc47ebfc0f
https://doi.org/10.1016/s0021-9150(99)00160-4

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Transforming growth factor β1 induces IL-1 receptor antagonist production and gene expression in rat vascular smooth muscle cells

Autor: Ettore Porreca, Franco Cuccurullo, Giovanna Baccante, Antonio Angelini, Marcella Reale, Maria Luisa Castellani, Concetta Di Febbo

Publikováno v: Atherosclerosis. 136:377-382

Atherosclerosis is an inflammatory-fibroproliferative process that may represent a possible milieu in which transforming growth factor-beta (TGF-beta) can be involved. Vascular smooth muscle cells (VSMC) may represent a source or a target of a large

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f71bf415210d911d81b6abe2269dbc
https://doi.org/10.1016/s0021-9150(97)00240-2

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Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo

Autor: Maria Domenica Guglielmi, Concetta Di Febbo, Marta L. Capone, Paola Patrignani, Valeria Moretta, Stefania Tacconelli, Maria G. Sciulli, Ivana Antonucci, Ettore Porreca, Liborio Stuppia, Emanuela Ricciotti, Giovanna Baccante

Publikováno v: Blood. 107:3572-3574

The recent demonstration that platelets express a functional toll-like receptor 4 (TLR4) prompted us to explore the influence of TLR4 polymorphisms (Asp299Gly alone or in combination with Thr399Ile) on thromboxane A(2) (TXA(2)) biosynthesis in vivo.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16086c46cccd2c871ee5af2882c712db
https://doi.org/10.1182/blood-2005-12-4811

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Down‐regulation of cyclooxygenase‐2 (COX‐2) by interleukin‐1 receptor antagonist in human monocytes

Autor: Marcella Reale, Pio Conti, Giovanna Baccante, M. Di Gioacchino, Franco Cuccurullo, Renato C. Barbacane, Ettore Porreca, M.L. Castellani, C. Di Febbo

Publikováno v: Immunology. 89:424-429

Cyclooxygenase (COX) is the key rate-limiting enzyme in the synthesis of prostanoids from arachidonic acid. Two isoforms of COX have been described in mammalian cells, referred to as cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cebadf83a672bb0f0fef50c435a5dcb
https://doi.org/10.1046/j.1365-2567.1996.d01-753.x

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Modulatory effects of heparin on cellular accumulation and cytotoxicity of doxorubicin in MRP1-overexpressing HL60/doxo cells

Autor: Antonio, Angelini, Giuliano, Ciofani, Giovanna, Baccante, Concetta, Di Febbo, Di Ilio, Carmine, Franco, Cuccurullo, Ettore, Porreca

Publikováno v: Anticancer research. 27(1A)

The overexpression of multidrug resistance protein (MRP1), associated with high levels of intracellular glutathione (GSH), is a well characterized mechanism of multidrug resistance (MDR) in several malignancies. Various chemosensitizers have been use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92fea7af133516507c877f0156841d5e
https://pubmed.ncbi.nlm.nih.gov/17352253

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Microsatellite polymorphism of the human leptin gene (LEP) and risk of cardiovascular disease

Autor: M Di Nisio, Valentina Gatta, S Pintor, Franco Cuccurullo, C. Di Febbo, Valeria Moretta, Ettore Porreca, Giovanna Baccante, Chiara Palka, Liborio Stuppia

Publikováno v: International journal of obesity 30.2 (2006): 209–213.
info:cnr-pdr/source/autori:E. PORRECA, C. DI FEBBO, S. PINTOR, G. BACCANTE, V. GATTA, V. MORETTA, M.D. NISIO, C. PALKA, F. CUCCURULLO, L. STUPPIA,/titolo:Microsatellite polymorphism of the human leptin gene (LEP) and risk of cardiovascular disease,/doi:/rivista:International journal of obesity/anno:2006/pagina_da:209/pagina_a:213/intervallo_pagine:209–213/volume:30.2

No data have been so far reported on the relationship between polymorphisms of LEP gene and cardiovascular disease.We genotyped a tetranucleotide repeat mapped in the 3'UTR of the LEP gene (LEP-tet) in 109 subjects with cardiovascular events and in 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42c4d82a03deb38d2f74da169776ae4
https://pubmed.ncbi.nlm.nih.gov/16261186

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