Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Giovanna, Alfano"'
Autor:
Jinhai Deng, Teng Pan, Dan Wang, Yourae Hong, Zaoqu Liu, Xingang Zhou, Zhengwen An, Lifeng Li, Giovanna Alfano, Gang Li, Luigi Dolcetti, Rachel Evans, Jose M Vicencio, Petra Vlckova, Yue Chen, James Monypenny, Camila Araujo De Carvalho Gomes, Gregory Weitsman, Kenrick Ng, Caitlin McCarthy, Xiaoping Yang, Zedong Hu, Joanna C Porter, Christopher J Tape, Mingzhu Yin, Fengxiang Wei, Manuel Rodriguez-Justo, Jin Zhang, Sabine Tejpar, Richard Beatson, Tony Ng
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2080-2108 (2024)
Abstract Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognized to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxal
Externí odkaz:
https://doaj.org/article/5559931ff7c94961b54686129b587544
Autor:
Paul R Barber, Rami Mustapha, Fabian Flores-Borja, Giovanna Alfano, Kenrick Ng, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Publikováno v:
eLife, Vol 11 (2022)
Background: Advanced head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict progression-free survival (PFS) with a mult
Externí odkaz:
https://doaj.org/article/f01407f956a24b9e8f9a0385ed5d4e28
Autor:
Naushin H Waseem, Sancy Low, Amna Z Shah, Deepa Avisetti, Pia Ostergaard, Michael Simpson, Katarzyna A Niemiec, Belen Martin-Martin, Hebah Aldehlawi, Saima Usman, Pak Sang Lee, Anthony P Khawaja, Jonathan B Ruddle, Ameet Shah, Ege Sackey, Alexander Day, Yuzhen Jiang, Geoff Swinfield, Ananth Viswanathan, Giovanna Alfano, Christina Chakarova, Heather J Cordell, David F Garway-Heath, Peng T Khaw, Shomi S Bhattacharya, Ahmad Waseem, Paul J Foster
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008721 (2020)
Current estimates suggest 50% of glaucoma blindness worldwide is caused by primary angle-closure glaucoma (PACG) but the causative gene is not known. We used genetic linkage and whole genome sequencing to identify Spermatogenesis Associated Protein 1
Externí odkaz:
https://doaj.org/article/d5c95c4f9b2048b1a0b64b97787b4d40
Autor:
Kenrick Ng, Giovanna Alfano, Fabian Flores-Borja, Rami Mustapha, Paul R Barber, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Publikováno v:
Elife, 11, 1-22
Elife, 11, pp. 1-22
Elife, 11, pp. 1-22
Background:Advanced head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict progression-free survival (PFS) with a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bede1585ff70f762d4065a1105f4dad
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/288117
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/288117
Autor:
Kenrick Ng, Giovanna Alfano, Fabian Flores-Borja, Rami Mustapha, Paul R Barber, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57c8dff8d520f1ca78e5f702a5e2731
https://doi.org/10.7554/elife.73288.sa2
https://doi.org/10.7554/elife.73288.sa2
Autor:
Shomi S. Bhattacharya, Emeline F. Nandrot, José-Alain Sahel, Veselina Moskova-Doumanova, Marie-Elise Lancelot, Giovanna Alfano, Maria Luz Bellido Diaz, Abhay Krishna, Isabelle Audo, Jordan A. Doumanov, Christina Zeitz, Paloma Dominguez Gimenez
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 15121-15140 (2013)
Mutations in BEST1 gene, encoding the bestrophin-1 (Best1) protein are associated with macular dystrophies. Best1 is predominantly expressed in the retinal pigment epithelium (RPE), and is inserted in its basolateral membrane. We investigated the cel
Externí odkaz:
https://doaj.org/article/1807d46c735d4dc89a03c582bdfc5da6
Autor:
Barbara Czub, Amna Z Shah, Giovanna Alfano, Przemysław M Kruczek, Christina F Chakarova, Shomi S Bhattacharya
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148678 (2016)
The significance of the ubiquitin-proteasome system (UPS) for protein degradation has been highlighted in the context of neurodegenerative diseases, including retinal dystrophies. TOPORS, a dual E3 ubiquitin and SUMO1 ligase, forms a component of the
Externí odkaz:
https://doaj.org/article/7e98c7f0cfa742648db2ac22267965a9
Autor:
Giovanna Alfano, Przemyslaw M Kruczek, Amna Z Shah, Barbara Kramarz, Glen Jeffery, Andrew C Zelhof, Shomi S Bhattacharya
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166397 (2016)
Mutations in the EYS gene are a common cause of autosomal recessive retinitis pigmentosa (arRP), yet the role of the EYS protein in humans is presently unclear. The aim of this study was to investigate the isoform structure, expression and potential
Externí odkaz:
https://doaj.org/article/66837ed7f73243bea3970114b720fb40
Autor:
Magnus T. Dillon, Giovanna Alfano, Jose Miguel Vicencio, Shahram Kordasti, Rami Mustapha, Paul R. Barber, Martin Forster, James W. Opzoomer, Kevin J. Harrington, James N. Arnold, Myria Galazi, Gregory Weitsman, Tony Ng, Luigi Dolcetti, Kenrick Ng, Jon Greenberg, Anthony C. C. Coolen, Fabian Flores-Borja, Felix Wong, Jana Doyle
BackgroundAdvanced Head and Neck Squamous Cell Cancer (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict Progression Free Survival (PFS) with a multivari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79651a6efe64429ee9f46cd394e9429
https://doi.org/10.1101/2021.09.22.21263942
https://doi.org/10.1101/2021.09.22.21263942
Autor:
Amna Z. Shah, Hebah Aldehlawi, Paul J. Foster, Ananth C. Viswanathan, Yuzhen Jiang, Peng T. Khaw, Saima Usman, Alexander C Day, Heather J. Cordell, Jonathan B Ruddle, Ahmad Waseem, Michael A. Simpson, Shomi S. Bhattacharya, Pak Sang Lee, Giovanna Alfano, Sancy Low, Naushin Waseem, Anthony P Khawaja, David F. Garway-Heath, Deepa R. Avisetti, Katarzyna A. Niemiec, Ege Sackey, Pia Ostergaard, Christina Chakarova, Belen Martin-Martin, Geoff Swinfield, Ameet Shah
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 4, p e1008721 (2020)
PLoS Genetics, Vol 16, Iss 4, p e1008721 (2020)
Current estimates suggest 50% of glaucoma blindness worldwide is caused by primary angle-closure glaucoma (PACG) but the causative gene is not known. We used genetic linkage and whole genome sequencing to identify Spermatogenesis Associated Protein 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d53d6538093b5657094313eca2ba0
http://europepmc.org/articles/PMC7233598
http://europepmc.org/articles/PMC7233598