Limitation of nitrogen source facilitated the production of nonmeiotic recombinants in Aspergillus nidulans

Autor: Giovana N. M. Esquissato, Omar Cléo Neves Pereira, Tais Susane Pereira, William Mário de Carvalho Nunes, Marialba Avezum Alves de Castro-Prado, Priscila Ayumi Sybuia, João Lúcio de Azevedo, Carlos Alexandre Zanutto, Gabriela de Castro‐Prado, João Alencar Pamphile, Heloá C. G. de Oliveira

Publikováno v: Journal of Basic Microbiology. 60:380-385

Aspergillus nidulans is a fungal model organism extensively used in genetic approaches. It may reproduce sexually and asexually, with a well-defined parasexual cycle. The current paper demonstrates that the limitation of nitrogen source facilitates t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4a4a483786e846d04d29525a462412
https://doi.org/10.1002/jobm.201900588

Gene homozygosis and mitotic recombination induced by camptothecin and irinotecan in Aspergillus nidulans diploid cells

Autor: P. A. S. R. Santos, Marialba Avezum Alves de Castro-Prado, Giovana N. M. Esquissato, Claudinéia Conationi da Silva Franco, Juliane Rocha de Sant'Anna, Lúcia J Rosada

Publikováno v: Anais da Academia Brasileira de Ciências, Volume: 86, Issue: 4, Pages: 1703-1710, Published: 21 OCT 2014
Anais da Academia Brasileira de Ciências, Vol 86, Iss 4, Pp 1703-1710 (2014)
Anais da Academia Brasileira de Ciências v.86 n.4 2014
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC

Mitotic recombination is a process involved in carcinogenesis which can lead to genetic loss through the loss of heterozygosity. The recombinogenic potentials of two anticancer drugs topoisomerase I inhibitors, camptothecin (CPT) and irinotecan (CPT-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fd7feab4de33ada18a1a0739fce245
https://doi.org/10.1590/0001-3765201420130106