Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Giovana B. Mantovani"'
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Supplementary Fig. S5  Growth characteristics of individual treated colonies. a, GR of all colonies used in Fig. 1e. Mean {plus minus} SD in red. b. Pairwise correlations among the three GRs. c. Mean {plus minus} variance of GR2 of U251 glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0936f0b39fd7b722de8069d01a21c9
https://doi.org/10.1158/0008-5472.22428630.v1
https://doi.org/10.1158/0008-5472.22428630.v1
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
File describing in more detail the methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e55e8ffce3211b6c6dcd1801375e5c6
https://doi.org/10.1158/0008-5472.22428618
https://doi.org/10.1158/0008-5472.22428618
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Video explaining the use of the DynaFit Desktop app and the R app and some applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7e15011535babbe5923e0002502ff9
https://doi.org/10.1158/0008-5472.22428582.v1
https://doi.org/10.1158/0008-5472.22428582.v1
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Several phenotypes that impact the capacity of cancer cells to survive and proliferate are dynamic. Here we used the number of cells in colonies as an assessment of fitness and devised a novel method called Dynamic Fitness Analysis (DynaFit) to measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48b6a7ed51e9ffa9c324a39f0ac7c40
https://doi.org/10.1158/0008-5472.c.6513075.v1
https://doi.org/10.1158/0008-5472.c.6513075.v1
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Supplementary Fig. S6  Growth characteristics of individual colonies. a, GR (mean {plus minus} variance) of U251 glioma colonies according to the colony size at the beginning of the analyzed GR during the presence of TMZ and b. after the withdr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b6767cf5f0aff4ef3ae0742bc79068
https://doi.org/10.1158/0008-5472.22428627
https://doi.org/10.1158/0008-5472.22428627
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Video describing the basic concepts of DynaFit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e05a8a2b1252ef911d945fe98342ffc
https://doi.org/10.1158/0008-5472.22428606
https://doi.org/10.1158/0008-5472.22428606
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Supplementary Fig. S1 DynaFit principles. a, numerical representation of the rationale presented in Fig. 1a. Cells with static growth rates will produce colonies with the same variance in growth rate, regardless of colony size (upper scenario).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33643e6dba02c3cc3871b344b2ba95c4
https://doi.org/10.1158/0008-5472.22428645.v1
https://doi.org/10.1158/0008-5472.22428645.v1
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Supplementary Fig. S3Analysis of the desynchronization of colonies of cells expressing FastFUCCI. a, FUCCI simulation for a single, synchronized colony with 4 cells. At a given time point, all cells in the colony will all either be green or not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07768039398aff04e225dd9a95a853ea
https://doi.org/10.1158/0008-5472.22428639.v1
https://doi.org/10.1158/0008-5472.22428639.v1
Autor:
Guido Lenz, Karine R. Begnini, Giovana R. Onzi, Andrew O. Silva, Sidia M. Callegari-Jacques, Alvaro Vigo, Eloisa Dalsin, Julia C. Marcolin, Carolina N. Santo, Giovana B. Mantovani, Thayana Monteiro, Daphne Torgo, Mauricio T. Tamborindeguy, Julieti H. Buss, Luiza C. Pereira, Jephesson A.F. Santos, Paula A. Bracco, Juliano L. Faccioni, Luana S. Lenz
Supplementary Fig. S2 DynaFit implementations. a, data collected from Supplementary Fig. S1c is given as input to the two DynaFit apps. The Python bootstrap app and the R predictive modeling app are based on different analytical strategies. b,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4899ce5a9083f0ec9177bf4b3089c14f
https://doi.org/10.1158/0008-5472.22428642.v1
https://doi.org/10.1158/0008-5472.22428642.v1
Autor:
Giovana Ravizzoni Onzi, Julia C Marcolin, Karine R Begnini, Luiza C. Pereira, Guido Lenz, Julieti H Buss, Eloisa Dalsin, Carolina Nunes Santo, Daphne Torgo, Giovana B Mantovani, Juliano Luiz Faccioni, Sidia M. Callegari-Jacques, Álvaro Vigo, Luana S. Lenz, Jephesson A.F. Santos, Paula A Bracco, Maurício Tavares Tamborindeguy, Thayana Monteiro, Andrew Oliveira Silva
Publikováno v:
Cancer research. 81(4)
Several phenotypes that impact the capacity of cancer cells to survive and proliferate are dynamic. Here we used the number of cells in colonies as an assessment of fitness and devised a novel method called Dynamic Fitness Analysis (DynaFit) to measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20be9e2b59aab381783008af1c9edf27
https://pubmed.ncbi.nlm.nih.gov/33355182
https://pubmed.ncbi.nlm.nih.gov/33355182
