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High-fat diet induces an ovulatory defect associated with dysregulated endothelin-2 in mice

Autor: Elena Silva, John D. Rice, Asma Giornazi, Emily M. Elliott, Natalie M. Hohos, Malgorzata E. Skaznik-Wikiel

Publikováno v: Reproduction (Cambridge, England). 161(3)

High-fat diet (HFD) consumption in female rodents causes impaired estrous cyclicity, fewer pups per litter, and dysregulation of key ovulatory genes suggesting that HFD-induced subfertility may be due to ovulatory dysfunction. To test this hypothesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cb0d96e35b50c63f495347c80e894c
https://pubmed.ncbi.nlm.nih.gov/33428588

Integrated stress response control of granulosa cell translation and proliferation during normal ovarian follicle development.

Autor: Llerena Cari E; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Aurora, CO, USA.; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Aurora, CO, USA., Hagen-Lillevik S; University of Utah School of Medicine, Department of Pediatrics and Department of Nutrition and Integrative Physiology, Salt Lake City, UT, USA., Giornazi A; University of Colorado-Boulder, Aurora, CO, USA., Post M; University of Colorado-Anschutz Medical Campus, Department of Pathology, Aurora, CO, USA., Komar AA; Cleveland State University, Center for Gene Regulation in Health and Disease (GRHD), Cleveland, OH, USA., Appiah L; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Academic Specialists in Obstetrics and Gynecology, Aurora, CO, USA., Bitler B; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Aurora, CO, USA., Polotsky AJ; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Aurora, CO, USA.; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Aurora, CO, USA., Santoro N; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Aurora, CO, USA.; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Aurora, CO, USA., Kieft J; University of Colorado-Anschutz Medical Campus, Department of Biochemistry and Molecular Genetics, Aurora, CO, USA., Lai K; University of Utah School of Medicine, Department of Pediatrics and Department of Nutrition and Integrative Physiology, Salt Lake City, UT, USA., Johnson J; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Aurora, CO, USA.; University of Colorado-Anschutz Medical Campus, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Aurora, CO, USA.

Publikováno v: Molecular human reproduction [Mol Hum Reprod] 2021 Aug 07; Vol. 27 (8).