Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Giorgos Gouridis"'
Autor:
Mary Kefi, Vasileia Balabanidou, Chara Sarafoglou, Jason Charamis, Gareth Lycett, Hilary Ranson, Giorgos Gouridis, John Vontas
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011226 (2023)
Contact insecticides are primarily used for the control of Anopheles malaria vectors. These chemicals penetrate mosquito legs and other appendages; the first barriers to reaching their neuronal targets. An ATP-Binding Cassette transporter from the H
Externí odkaz:
https://doaj.org/article/a3e1618230854df5aa258abc451d826b
Autor:
Srinath Krishnamurthy, Marios-Frantzeskos Sardis, Nikolaos Eleftheriadis, Katerina E. Chatzi, Jochem H. Smit, Konstantina Karathanou, Giorgos Gouridis, Athina G. Portaliou, Ana-Nicoleta Bondar, Spyridoula Karamanou, Anastassios Economou
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110346- (2022)
Summary: Protein machines undergo conformational motions to interact with and manipulate polymeric substrates. The Sec translocase promiscuously recognizes, becomes activated, and secretes >500 non-folded preprotein clients across bacterial cytoplasm
Externí odkaz:
https://doaj.org/article/bdd7e0f8f72b43d599e95709a51696f3
Autor:
Evelyn Ploetz, Gea K. Schuurman-Wolters, Niels Zijlstra, Amarins W. Jager, Douglas A. Griffith, Albert Guskov, Giorgos Gouridis, Bert Poolman, Thorben Cordes
Publikováno v:
Open Biology, Vol 11, Iss 4 (2021)
The ATP-binding cassette transporter GlnPQ is an essential uptake system that transports glutamine, glutamic acid and asparagine in Gram-positive bacteria. It features two extra-cytoplasmic substrate-binding domains (SBDs) that are linked in tandem t
Externí odkaz:
https://doaj.org/article/2ff88b83b44648049ceedd5d0968fc25
Autor:
Giorgos Gouridis, Bianca Hetzert, Kristin Kiosze-Becker, Marijn de Boer, Holger Heinemann, Elina Nürenberg-Goloub, Thorben Cordes, Robert Tampé
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 723-734.e6 (2019)
Summary: The twin-ATPase ABCE1 has a vital function in mRNA translation by recycling terminated or stalled ribosomes. As for other functionally distinct ATP-binding cassette (ABC) proteins, the mechanochemical coupling of ATP hydrolysis to conformati
Externí odkaz:
https://doaj.org/article/31cc0c65d4e145c8a78ca47f12d5f3d0
Autor:
Marijn de Boer, Giorgos Gouridis, Ruslan Vietrov, Stephanie L Begg, Gea K Schuurman-Wolters, Florence Husada, Nikolaos Eleftheriadis, Bert Poolman, Christopher A McDevitt, Thorben Cordes
Publikováno v:
eLife, Vol 8 (2019)
Substrate-binding proteins (SBPs) are associated with ATP-binding cassette importers and switch from an open to a closed conformation upon substrate binding, providing specificity for transport. We investigated the effect of substrates on the conform
Externí odkaz:
https://doaj.org/article/15f0005b2cc34729a8f4bc4b49571c6b
Autor:
Jasper H. M. van der Velde, Jens Oelerich, Jingyi Huang, Jochem H. Smit, Atieh Aminian Jazi, Silvia Galiani, Kirill Kolmakov, Giorgos Gouridis, Christian Eggeling, Andreas Herrmann, Gerard Roelfes, Thorben Cordes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Synthetic organic fluorophores are powerful tools for bioimaging, but frequently display shortened observation times and signal fluctuations. Here, the authors report a general method to covalently label a biomolecule with a fluorophore and photostab
Externí odkaz:
https://doaj.org/article/77b60fed403541aa9d01f52a52fbdb39
Autor:
Jasper H. M. van der Velde, Jens Oelerich, Jingyi Huang, Jochem H. Smit, Atieh Aminian Jazi, Silvia Galiani, Kirill Kolmakov, Giorgos Gouridis, Christian Eggeling, Andreas Herrmann, Gerard Roelfes, Thorben Cordes
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 7: Article number: 10144 (2016); Published 11 January 2016, Updated 24 July 2018 The original version of this Article omitted the following from the Acknowledgements: ‘This work was also financed by an ERC starting grant ‘SM
Externí odkaz:
https://doaj.org/article/40a0648d673f4e3a9ea76ea1afaed823
Autor:
Jasper H. M. van der Velde, Jens Oelerich, Jingyi Huang, Jochem H. Smit, Atieh Aminian Jazi, Silvia Galiani, Kirill Kolmakov, Giorgos Gouridis, Christian Eggeling, Andreas Herrmann, Gerard Roelfes, Thorben Cordes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number: 10144 (2016); Published: 11 January 2016; Updated: 16 November 2017 This Article contains an error in Fig. 4. Figure 4b shows the structure of the rhodamine dye Alexa488, not the Alexa555 used in this work. Th
Externí odkaz:
https://doaj.org/article/da37e0a1fd124b9886d8544576d05868
Autor:
Mary Kefi, Vasileia Balabanidou, Chara Sarafoglou, Jason Charamis, Gareth Lycett, Hilary Ranson, Giorgos Gouridis, John Vontas
Contact insecticides are primarily used for the control ofAnophelesmalaria vectors. These chemicals penetrate mosquito legs and other appendages, the first barrier to reaching their neuronal targets. An ATP-Binding Cassette transporter from the H fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ac742d1267efe9a68b1d1e92972d05
https://doi.org/10.1101/2023.02.21.529359
https://doi.org/10.1101/2023.02.21.529359
Autor:
Spyridoula Karamanou, Alexandra Tsirigotaki, Alexander Dömling, Thorben Cordes, Martin Zacharias, Yusran Abdillah Muthahari, Douglas A. Griffith, Niels Zijlstra, Giorgos Gouridis, Konstantinos Tassis, Charalambos Pozidis, Marijn de Boer, Anastassios Economou, Ruixue Xu, Yovin Sugijo, Nikolaos Eleftheriadis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118(49):e2026165118. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Proteins conduct numerous complex biological functions by use of tailored structural dynamics. The molecular details of how these emerged from ancestral peptides remains mysterious. How does nature utilize the same repertoire of folds to