Zobrazeno 1 - 10 of 863 pro vyhledávání: '"Giorgioni, A."'
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Akademický článek
Revolutionizing CAR T-Cell Therapies: Innovations in Genetic Engineering and Manufacturing to Enhance Efficacy and Accessibility.
Autor: Giorgioni, Lorenzo1 (AUTHOR) lorenzo.giorgioni@uniroma1.it, Ambrosone, Alessandra2 (AUTHOR) alessandra.ambrosone@guest.iss.it, Cometa, Maria Francesca2 (AUTHOR) mariafrancesca.cometa@iss.it, Salvati, Anna Laura3 (AUTHOR) robert.nistico@gmail.com, Nisticò, Robert3,4 (AUTHOR), Magrelli, Armando2 (AUTHOR) armando.magrelli@iss.it
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10365. 22p.
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2
Akademický článek
Revolutionizing CAR T-Cell Therapies: Innovations in Genetic Engineering and Manufacturing to Enhance Efficacy and Accessibility
Autor: Lorenzo Giorgioni, Alessandra Ambrosone, Maria Francesca Cometa, Anna Laura Salvati, Robert Nisticò, Armando Magrelli
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 19, p 10365 (2024)
Chimeric antigen receptor (CAR) T-cell therapy has achieved notable success in treating hematological cancers but faces significant challenges in solid-tumor treatment and overall efficacy. Key limitations include T-cell exhaustion, tumor relapse, im
Externí odkaz: https://doaj.org/article/822099459a194a81a2f37623b96d96ab
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5
Akademický článek
Primary and Secondary Geochemical Signals in the Chemical Composition of Exoskeleton of Corumbella werneri (Tamengo Formation, Corumbá Group, Brazil): A Pilot Study
Autor: Ana Valéria Alves Calmon Almeida, Martino Giorgioni, Detlef Hans Gert Walde, Dermeval Aparecido Do Carmo, Guilherme de Oliveira Gonçalves
Publikováno v: Minerals, Vol 14, Iss 8, p 784 (2024)
The study of Neoproterozoic carbonate sequences is complicated due to several variables influencing the geochemical and mineralogical composition, compounded by the scarcity of environmental analogs. The Tamengo Formation in the Corumbá Group is one
Externí odkaz: https://doaj.org/article/61d39b50e6634522abd27b02ef644c25
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6
Akademický článek
Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes
Autor: Federica Matteucci, Marta Ferrati, Eleonora Spinozzi, Alessia Piergentili, Fabio Del Bello, Gianfabio Giorgioni, Leonardo Sorci, Riccardo Petrelli, Loredana Cappellacci
Publikováno v: Pharmaceuticals, Vol 17, Iss 6, p 739 (2024)
Nicotinamide adenine dinucleotide (NAD) cofactor metabolism plays a significant role in cancer development. Tumor cells have an increased demand for NAD and ATP to support rapid growth and proliferation. Limiting the amount of available NAD by target
Externí odkaz: https://doaj.org/article/1e8c3736a20645b2b1e32215f2ff8eb2
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9
Akademický článek
The neuromedin U system: Pharmacological implications for the treatment of obesity and binge eating behavior
Autor: Luca Botticelli, Emanuela Micioni Di Bonaventura, Fabio Del Bello, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Alessandro Bonifazi, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura
Publikováno v: Pharmacological Research, Vol 195, Iss , Pp 106875- (2023)
Neuromedin U (NMU) is a bioactive peptide produced in the gut and in the brain, with a role in multiple physiological processes. NMU acts by binding and activating two G protein coupled receptors (GPCR), the NMU receptor 1 (NMU-R1), which is predomin
Externí odkaz: https://doaj.org/article/a5eef850d2c64716b12e4792c1bcf571
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10
Akademický článek
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