Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Giorgio Rizzi"'
Publikováno v:
Advanced Science, Vol 9, Iss 7, Pp n/a-n/a (2022)
Abstract Parkinson's disease (PD) results from selective loss of substantia nigra dopaminergic (SNc DA) neurons, and is primarily caused by excessive activity‐related Ca2+ oscillations. Although L‐type voltage‐gated calcium channel blockers (CC
Externí odkaz:
https://doaj.org/article/514762950f1c473a924c9848f3046e0d
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The red nucleus (RN) is a midbrain nucleus known to be involved in the fine control of limb movements, but its role in motor learning is unclear. Here, the authors identified a neuronal population within the red nucleus, co-expressing Vglut2, PV and
Externí odkaz:
https://doaj.org/article/0114f8e45fe84971bb3a48afc810a898
Autor:
Ryosuke Kojima, Daniel Bojar, Giorgio Rizzi, Ghislaine Charpin-El Hamri, Marie Daoud El-Baba, Pratik Saxena, Simon Ausländer, Kelly R. Tan, Martin Fussenegger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Exosomes function as intercellular information transmitters and are candidates for delivery of therapeutic agents. Here the authors present EXOtic, a synthetic biology device for in-situ production of designer exosomes and demonstrate in vivo applica
Externí odkaz:
https://doaj.org/article/0e6a2ce92e194d368bbcb60650f4592b
Autor:
Giorgio Rizzi, Kelly R. Tan
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2184-2198.e4 (2019)
Summary: Locomotion relies on the activity of basal ganglia networks, where, as the output, the substantia nigra pars reticulata (SNr) integrates incoming signals and relays them to downstream areas. The cellular and circuit substrates of such a comp
Externí odkaz:
https://doaj.org/article/90681193f54d4466ac8047ce32c18080
Autor:
Jolien S. van Campen, Ellen V. S. Hessel, Kirsten Bohmbach, Giorgio Rizzi, Paul J. Lucassen, Sada Lakshmi Turimella, Eduardo H. L. Umeoka, Gideon F. Meerhoff, Kees P. J. Braun, Pierre N. E. de Graan, Marian Joëls
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Stress is the most frequently self-reported seizure precipitant in patients with epilepsy. Moreover, a relation between ear stress and epilepsy has been suggested. Although ear stress and stress hormones are known to influence seizure threshold in ro
Externí odkaz:
https://doaj.org/article/cb2cd330eec9443cb441d84d3bce8e63
Autor:
Giorgio Rizzi, Kelly R. Tan
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2017)
Data from the World Health Organization (National Institute on Aging, 2011) and the National Institutes of Health (He et al., 2016) predicts that while today the worldwide population over 65 years of age is estimated around 8.5%, this number will rea
Externí odkaz:
https://doaj.org/article/62575743a7044f5fa87dc4910d7e8c53
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(7)
Parkinson's disease (PD) results from selective loss of substantia nigra dopaminergic (SNc DA) neurons, and is primarily caused by excessive activity-related Ca
Recent studies suggest that the Zona Incerta (ZI) plays a role in fear learning and recall. However, there is a clear gap in knowledge as to whether the ZI can encode fear evoking threats and cues that predict them. Here, we subject mice to a classic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41755f651946cddd1e7fd57641195cde
https://doi.org/10.1101/2021.07.31.454576
https://doi.org/10.1101/2021.07.31.454576
The firing activity of dorso-medial-striatal-cholinergic interneurons (dmCINs) is a neural correlate of classical conditioning. dmCINs are tonically active and briefly pause in response to salient stimuli. This mediates the acquisition of the associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159a0ec5377e127806e847237829a481
Autor:
Daniel Bojar, Marie Daoud El-Baba, Simon Ausländer, Ghislaine Charpin-El Hamri, Kelly R. Tan, Ryosuke Kojima, Giorgio Rizzi, Pratik Saxena, Martin Fussenegger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, 9 (1)
Nature Communications, 9 (1)
Exosomes are cell-derived nanovesicles (50–150 nm), which mediate intercellular communication, and are candidate therapeutic agents. However, inefficiency of exosomal message transfer, such as mRNA, and lack of methods to create designer exosomes h