Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Giorgio Allemanni"'
Autor:
Barbara Banelli, Alessandra Forlani, Giorgio Allemanni, Anna Morabito, Maria Pia Pistillo, Massimo Romani
Publikováno v:
International Journal of Genomics, Vol 2017 (2017)
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal therapy, is an invariably lethal cancer with a life expectancy that depends on the tumor subtype but, even in the most favorable cases, rarely exceeds 2 years. Epig
Externí odkaz:
https://doaj.org/article/72b93e35ff664d1283af9bfbffd00e9f
Autor:
Barbara Banelli, Domenico Franco Merlo, Giorgio Allemanni, Alessandra Forlani, Massimo Romani
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63253 (2013)
Approximately 20% of stage 4 high-risk neuroblastoma patients are alive and disease-free 5 years after disease onset while the remaining experience rapid and fatal progression. Numerous findings underline the prognostic role of methylation of defined
Externí odkaz:
https://doaj.org/article/10355198ee984566a382eec50b819540
Autor:
Claudio Brigati, Barbara Banelli, Angela di Vinci, Ida Casciano, Giorgio Allemanni, Alessandra Forlani, Luana Borzì, Massimo Romani
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
We summarize recent findings linking inflammatory hypoxia to chromatin modifications, in particular to repressive histone signatures. We focus on the role of Hypoxia-Induced Factor-1 in promoting the activity of specific histone demethylases thus dee
Externí odkaz:
https://doaj.org/article/581006e11b054865af48457e587ef42d
Autor:
Tullio Florio, Massimo Romani, Roberto Würth, Giorgio Allemanni, Barbara Banelli, Alessandra Forlani, Antonio Daga, Roberta Carosio, Daniela Marubbi, Alessandra Pattarozzi, Elisa Carra, Federica Parodi, Federica Barbieri
Publikováno v:
Cell Cycle. 14:3418-3429
Notwithstanding current multimodal treatment, including surgery, radiotherapy and chemotherapy with temozolomide (TMZ), median survival of glioblastoma (GBM) patients is about 14 months, due to the rapid emergence of cell clones resistant to treatmen
Autor:
Maria Pia Pistillo, Anna Morabito, Massimo Romani, Giorgio Allemanni, Barbara Banelli, Alessandra Forlani
Publikováno v:
International Journal of Genomics
International Journal of Genomics, Vol 2017 (2017)
International Journal of Genomics, Vol 2017 (2017)
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal therapy, is an invariably lethal cancer with a life expectancy that depends on the tumor subtype but, even in the most favorable cases, rarely exceeds 2 years. Epig
Autor:
Massimo Romani, Alessandra Forlani, Maria Pia Pistillo, Daniela Marubbi, Barbara Banelli, Giorgio Allemanni, Aldo Profumo, Antonio Daga
Publikováno v:
Oncotarget
// Barbara Banelli 1, 2, * , Antonio Daga 3, * , Alessandra Forlani 1, * , Giorgio Allemanni 1 , Daniela Marubbi 3, 4 , Maria Pia Pistillo 1 , Aldo Profumo 5 , Massimo Romani 1 1 Laboratory of Tumor Epigenetics, IRCCS AOU San Martino–IST, Genova, I
Autor:
Marco Maugeri, Cinzia Di Pietro, Marco Ragusa, Maria Pia Pistillo, Barbara Banelli, Francesco Paolo Schena, Davide Barbagallo, Fabio Sallustio, Alessandra Forlani, Michele Purrello, Giorgio Allemanni, Ida Casciano, Federica Parodi, Roberta Carosio, Massimo Romani
Publikováno v:
Biochimica et biophysica acta. 1859(12)
In neuroblastoma, the epigenetic landscape is more profoundly altered in aggressive compared to lower grade tumors and the concomitant hypermethylation of many genes, defined as "methylator phenotype", has been associated with poor outcome. DNA methy
Autor:
Barbara Banelli, Massimo Romani, Luana Borzì, Angela Di Vinci, Alessandra Forlani, Claudio Brigati, Ida Casciano, Giorgio Allemanni
Publikováno v:
Laboratory Investigation. 92:458-465
Epigenetic alterations are hallmarks of cancer and powerful biomarkers, whose clinical utilization is made difficult by the absence of standardization and of common methods of data interpretation. The coordinate methylation of many loci in cancer is
Autor:
Ida Casciano, Massimo Romani, Alessandra Forlani, Barbara Banelli, Giorgio Allemanni, Claudio Brigati, Angela Di Vinci
Publikováno v:
Breast Care. 5:75-80
In 1940, it was demonstrated that free DNA could be identified in the bloodstream. It was later shown that circulating nucleic acids (CNA), both DNA and RNA, are present in several neoplastic and non-neoplastic diseases, and that in cancer they origi
Autor:
Giorgio Allemanni, Barbara Banelli, Ida Casciano, Ilaria Gelvi, Angela Di Vinci, Massimo Romani
Publikováno v:
Laboratory Investigation. 86:297-303
Cancer cells release their DNA into the patient's bodily fluids and cancer-specific signatures can be recognized in the circulating DNA. The aberrant methylation of CpG-rich regions in gene promoter sequences is an early marker of cell transformation