Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giorgia Pedini"'
Autor:
Giorgia Pedini, Mariachiara Buccarelli, Fabrizio Bianchi, Laura Pacini, Giulia Cencelli, Quintino Giorgio D’Alessandris, Maurizio Martini, Stefano Giannetti, Franceschina Sasso, Valentina Melocchi, Maria Giulia Farace, Tilmann Achsel, Luigi M. Larocca, Lucia Ricci-Vitiani, Roberto Pallini, Claudia Bagni
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Converging evidence indicates that the Fragile X Messenger Ribonucleoprotein (FMRP), which absent or mutated in Fragile X Syndrome (FXS), plays a role in many types of cancers. However, while FMRP roles in brain development and function have
Externí odkaz:
https://doaj.org/article/5dd121580cbe4c19bab177623695c5f7
Autor:
Antonella Ferrante, Zaira Boussadia, Antonella Borreca, Cinzia Mallozzi, Giorgia Pedini, Laura Pacini, Antonella Pezzola, Monica Armida, Fabrizio Vincenzi, Katia Varani, Claudia Bagni, Patrizia Popoli, Alberto Martire
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract In fragile X syndrome (FXS) the lack of the fragile X mental retardation protein (FMRP) leads to exacerbated signaling through the metabotropic glutamate receptors 5 (mGlu5Rs). The adenosine A2A receptors (A2ARs), modulators of neuronal dama
Externí odkaz:
https://doaj.org/article/baf6b0c89ced4144a4007e3eb7e8cab2
Autor:
Adam C. O’Neill, Fatma Uzbas, Giulia Antognolli, Florencia Merino, Kalina Draganova, Alex Jäck, Sirui Zhang, Giorgia Pedini, Julia P. Schessner, Kimberly Cramer, Aloys Schepers, Fabian Metzger, Miriam Esgleas, Pawel Smialowski, Renzo Guerrini, Sven Falk, Regina Feederle, Saskia Freytag, Zefeng Wang, Melanie Bahlo, Ralf Jungmann, Claudia Bagni, Georg H. H. Borner, Stephen P. Robertson, Stefanie M. Hauck, Magdalena Götz
The centrosome provides an intracellular anchor for the cytoskeleton, regulating cell division, cell migration, and cilia formation. We used spatial proteomics to elucidate protein interaction networks at the centrosome of human induced pluripotent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588091084cf7a739ee133535ecb72bb4
https://hdl.handle.net/2108/317019
https://hdl.handle.net/2108/317019
Autor:
Giorgia Pedini, Claudia Bagni
Publikováno v:
Neuron. 110(7)
Mutations in epigenetic factors are associated with autism spectrum disorder (ASD). In this issue of Neuron, Yan et al. (2022) show that the antagonism of ASH1L and PRC2 switches the equilibrium of histone methylation at the ephrin receptor A7 locus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78852c002952bd64ac3d6b5cb4851178
https://pubmed.ncbi.nlm.nih.gov/35081333
https://pubmed.ncbi.nlm.nih.gov/35081333
Autor:
L. Mannucci, Dario Serio, Alessandra Rufini, Laura Pacini, Giorgia Pedini, Florence Malisan, Roberto Testi, Damiano Sergio Massaro, Luca Panarello, Monica Benini, Nicola Toschi, Ivano Condò, Giorgia Alaimo, Giulia Alfedi, Riccardo Luffarelli, Silvia Fortuni
Publikováno v:
Movement Disorders. 34:323-334
BACKGROUND Friedreich's ataxia is an autosomal-recessive cerebellar ataxia caused by mutation of the frataxin gene, resulting in decreased frataxin expression, mitochondrial dysfunction, and oxidative stress. Currently, no treatment is available for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a32c06650c832c8ba665ae0e1d2419
https://doi.org/10.1002/mds.27604
https://doi.org/10.1002/mds.27604
Autor:
Claudia Bagni, Zaira Boussadia, Antonella Borreca, Fabrizio Vincenzi, Giorgia Pedini, Katia Varani, Antonella Ferrante, Cinzia Mallozzi, Patrizia Popoli, Monica Armida, Antonella Pèzzola, Laura Pacini, Alberto Martire
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
In fragile X syndrome (FXS) the lack of the fragile X mental retardation protein (FMRP) leads to exacerbated signaling through the metabotropic glutamate receptors 5 (mGlu5Rs). The adenosine A2A receptors (A2ARs), modulators of neuronal damage, could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ea5631829468869d754b489cd28ac5
https://doi.org/10.1038/s41398-021-01238-5
https://doi.org/10.1038/s41398-021-01238-5
Autor:
Davide Di Fusco, Giovanni Monteleone, Giorgia Pedini, Eleonora Franzè, Vincenzo Dinallo, Giuseppe S. Sica, Ivan Monteleone, Pierpaolo Sileri, Irene Marafini, Claudia Bagni, Antonio Di Grazia, Eleonora Rosina, Carmine Stolfi, Federica Laudisi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The fragile X mental retardation protein (FMRP) affects multiple steps of the mRNA metabolism during brain development and in different neoplastic processes. However, the contribution of FMRP in colon carcinogenesis has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab99c822c3df1f5cf7829928c626cf2
http://hdl.handle.net/2108/303240
http://hdl.handle.net/2108/303240
Autor:
Matías A. Avila, Giuseppe Perrone, Leticia Colyn, Claudia Bagni, Rocco Simone Flammia, Maite G. Fernandez-Barrena, Maria Francesconi, Laura D’Andrea, Sergio Morini, Maria Zingariello, Daniela Righi, M. Ujue Latasa, Francesca Zalfa, Francesco Pantano, Giorgia Pedini, Mario Falchi, Rosa Alba Rana, Simone Carotti
Publikováno v:
Oncogene
Intrahepatic cholangiocarcinoma (iCCA) is a rare malignancy of the intrahepatic biliary tract with a very poor prognosis. Although some clinicopathological parameters can be prognostic factors for iCCA, the molecular prognostic markers and potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878fc54fa49f5d5ec568c7f95598a657
http://hdl.handle.net/11573/1639473
http://hdl.handle.net/11573/1639473
Autor:
Antonella, Ferrante, Zaira, Boussadia, Antonella, Borreca, Cinzia, Mallozzi, Giorgia, Pedini, Laura, Pacini, Antonella, Pezzola, Monica, Armida, Fabrizio, Vincenzi, Katia, Varani, Claudia, Bagni, Patrizia, Popoli, Alberto, Martire
Publikováno v:
Translational Psychiatry
In fragile X syndrome (FXS) the lack of the fragile X mental retardation protein (FMRP) leads to exacerbated signaling through the metabotropic glutamate receptors 5 (mGlu5Rs). The adenosine A2A receptors (A2ARs), modulators of neuronal damage, could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37b86a5dff71050f1094b3a80ca10577
https://pubmed.ncbi.nlm.nih.gov/33547274
https://pubmed.ncbi.nlm.nih.gov/33547274
Autor:
Giulia Cencelli, Giorgia Pedini, Laura Pacini, Yunsheng He, Rob Willemsen, Laura D'Andrea, Fabrizio Gasparini, Randi J Hagerman, Baltazar Gomez-Mancilla, Marwa Eldeeb, Izabela Rozenberg, Claudia Bagni, Flora Tassone, Sébastien Jacquemont, Aia E. Jønch
Publikováno v:
Human molecular genetics, vol 27, iss 21
Jacquemont, S, Pacini, L, Jønch, A E, Cencelli, G, Rozenberg, I, He, Y, D'Andrea, L, Pedini, G, Eldeeb, M, Willemsen, R, Gasparini, F, Tassone, F, Hagerman, R, Gomez-Mancilla, B & Bagni, C 2018, ' Protein synthesis levels are increased in a subset of individuals with Fragile X syndrome ', Human Molecular Genetics, vol. 27, no. 12, pp. 2039–2051 . https://doi.org/10.1093/hmg/ddy099
Human Molecular Genetics
Human molecular genetics, vol 27, iss 12
Human Molecular Genetics, 27(12), 2039-2051. Oxford University Press
Human molecular genetics, vol. 27, no. 12, pp. 2039-2051
Human Molecular Genetics, vol. 27, no. 21, pp. 3825
Jacquemont, S, Pacini, L, Jønch, A E, Cencelli, G, Rozenberg, I, He, Y, D'Andrea, L, Pedini, G, Eldeeb, M, Willemsen, R, Gasparini, F, Tassone, F, Hagerman, R, Gomez-Mancilla, B & Bagni, C 2018, ' Protein synthesis levels are increased in a subset of individuals with Fragile X syndrome ', Human Molecular Genetics, vol. 27, no. 12, pp. 2039–2051 . https://doi.org/10.1093/hmg/ddy099
Human Molecular Genetics
Human molecular genetics, vol 27, iss 12
Human Molecular Genetics, 27(12), 2039-2051. Oxford University Press
Human molecular genetics, vol. 27, no. 12, pp. 2039-2051
Human Molecular Genetics, vol. 27, no. 21, pp. 3825
Fragile X syndrome (FXS) is a monogenic form of intellectual disability and autism spectrum disorder caused by the absence of the fragile X mental retardation protein (FMRP). In biological models for the disease, this leads to upregulated mRNA transl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51f22e11b6b6db3f38b4f481bd98ed9
https://pure.eur.nl/en/publications/52849c35-faa8-4ac8-b2e7-8d6b7897e821
https://pure.eur.nl/en/publications/52849c35-faa8-4ac8-b2e7-8d6b7897e821