Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Giorgia Massacci"'
Autor:
Giorgia Massacci, Veronica Venafra, Maximilian Zwiebel, Maria Wahle, Rocco Cerroni, Jacopo Bissacco, Livia Perfetto, Vito Michienzi, Alessandro Stefani, Nicola Biagio Mercuri, Tommaso Schirinzi, Francesca Sacco
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106622- (2024)
The complexity and heterogeneity of PD necessitate advanced diagnostic and prognostic tools to elucidate its molecular mechanisms accurately. In this study, we addressed this challenge by conducting a pilot phospho-proteomic analysis of peripheral bl
Externí odkaz:
https://doaj.org/article/950cc03d9ec44c17b6dac7150ecc5c5c
Autor:
Sara Latini, Veronica Venafra, Giorgia Massacci, Valeria Bica, Simone Graziosi, Giusj Monia Pugliese, Marta Iannuccelli, Filippo Frioni, Gessica Minnella, John Donald Marra, Patrizia Chiusolo, Gerardo Pepe, Manuela Helmer Citterich, Dimitros Mougiakakos, Martin Böttcher, Thomas Fischer, Livia Perfetto, Francesca Sacco
Publikováno v:
eLife, Vol 12 (2024)
Currently, the identification of patient-specific therapies in cancer is mainly informed by personalized genomic analysis. In the setting of acute myeloid leukemia (AML), patient-drug treatment matching fails in a subset of patients harboring atypica
Externí odkaz:
https://doaj.org/article/046f6248d0ed4a4e8ed3337d150c805e
Autor:
Francesca Sacco, Giorgia Massacci, Venafra Veronica, Valeria Bica, Sara Latini, Thomas Fischer, Dimitrios Mougiakakos, Martin Böttcher, Livia Perfetto, Natalie Krahmer, Felix Klingelhuber, Monia Pugliese
Publikováno v:
HemaSphere, Vol 7, p e310578d (2023)
Externí odkaz:
https://doaj.org/article/65da723653484a1c9710aed59454bb77
Autor:
Federica Riccio, Elisa Micarelli, Riccardo Secci, Giulio Giuliani, Simone Vumbaca, Giorgia Massacci, Luisa Castagnoli, Claudia Fuoco, Gianni Cesareni
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Repurposing of drugs for new therapeutic use has received considerable attention for its potential to limit time and cost of drug development. Here we present a new strategy to identify chemicals that are likely to promote a desired phenotyp
Externí odkaz:
https://doaj.org/article/59d70f3c5f0241fa9bba1d69b88a806a
Autor:
Giulio Giuliani, Simone Vumbaca, Claudia Fuoco, Cesare Gargioli, Ezio Giorda, Giorgia Massacci, Alessandro Palma, Alessio Reggio, Federica Riccio, Marco Rosina, Maria Vinci, Luisa Castagnoli, Gianni Cesareni
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-24 (2021)
Abstract The term micro-heterogeneity refers to non-genetic cell to cell variability observed in a bell-shaped distribution of the expression of a trait within a population. The contribution of micro-heterogeneity to physiology and pathology remains
Externí odkaz:
https://doaj.org/article/0ccf14b53959408ea9dfa6c7a33e6a4a
Publikováno v:
Proteomes, Vol 9, Iss 2, p 19 (2021)
FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor clinical outcome, relapse and chemotherapeutic resistance. Elucidating the molecular mechanisms underlying FLT3-depende
Externí odkaz:
https://doaj.org/article/b9fd26c078284b38b726ed59b7ebe481
Autor:
Giusj Monia Pugliese, Veronica Venafra, Valeria Bica, Giorgia Massacci, Sara Latini, Simone Graziosi, Thomas Fischer, Dimitrios Mougiakakos, Martin Boettcher, Livia Perfetto, Francesca Sacco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6823b3b7fc65b9c34e70240e5184b922
https://hdl.handle.net/11573/1680075
https://hdl.handle.net/11573/1680075
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2456
Over the recent years, mass spectrometry (MS)-based proteomics has undergone dramatic advances in sample preparation, instrumentation, and computational methods. Here, we describe in detail, how a workflow quantifies global protein phosphorylation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d619bd19211d67cee1452de6b053f5d
https://pubmed.ncbi.nlm.nih.gov/35612739
https://pubmed.ncbi.nlm.nih.gov/35612739
Autor:
Giorgia Massacci, Veronica Venafra, Sara Latini, Valeria Bica, Giusj Monia Pugliese, Felix Klingelhuber, Natalie Krahmer, Thomas Fischer, Dimitrios Mougiakakos, Martin Boettcher, Livia Perfetto, Francesca Sacco
SummaryInternal tandem duplications (ITDs) in the FLT3 gene are frequently identified and confer a poor prognosis in patient affected by acute myeloid leukemia (AML). The insertion site of the ITDs in FLT3 significantly impacts the sensitivity to tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f44f0b8e756995d2969918634882a9
https://doi.org/10.1101/2022.05.16.492070
https://doi.org/10.1101/2022.05.16.492070
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6962b8784db2ce4b473f7c11c0676a6
https://doi.org/10.1007/978-1-0716-2124-0_9
https://doi.org/10.1007/978-1-0716-2124-0_9