Výsledky vyhledávání - "Giorgia Luciani"

Muscular effects of orexin A on the mouse duodenum: mechanical and electrophysiological studies

Autor: Roberta Squecco, Fabio Francini, Giorgia Luciani, Rachele Garella, Maria Caterina Baccari

Publikováno v: The Journal of Physiology. 589:5231-5246

Orexin A (OXA) has been reported to influence gastrointestinal motility, acting at both central and peripheral neural levels. The aim of the present study was to evaluate whether OXA also exerts direct effects on the duodenal smooth muscle. The possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be32488b0e0606c5c4dedbec178ef110
https://doi.org/10.1113/jphysiol.2011.214940

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Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation

Autor: Roberta Squecco, Francesca Bini, Giorgia Luciani, Elisabetta Meacci, Sandra Zecchi-Orlandini, Francesca Sbrana, Flaminia Chellini, Chiara Sassoli, Lucia Formigli, Maria Martinesi, Fabio Francini

Publikováno v: Journal of Cell Science. 122:1322-1333

Transient receptor potential canonical (TRPC) channels provide cation and Ca2+ entry pathways, which have important regulatory roles in many physio-pathological processes, including muscle dystrophy. However, the mechanisms of activation of these cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b853471c246416bd57915c432d659db
https://doi.org/10.1242/jcs.035402

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Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells

Autor: Paola Bruni, Giorgia Luciani, L. Borgognoni, Caterina Bernacchioni, Susanna Benvenuti, Paola Luciani, Paola Nincheri, Chiara Donati, Roberta Squecco, Fabio Francini

Publikováno v: Cellular and Molecular Life Sciences. 66:1741-1754

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid which regulates multiple biological parameters in a number of cell types, including stem cells. Here we report, for the first time, that S1P dose-dependently stimulates differentiation of adip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7374acb19c1ed413b84f05730fab03c
https://doi.org/10.1007/s00018-009-9181-8

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The vitamin D receptor agonist elocalcitol upregulates L-type calcium channel activity in human and rat bladder

Autor: Rosa Mancina, Roberta Squecco, Linda Vignozzi, Giorgia Luciani, Fabio Francini, Benedetta Fibbi, Paola Failli, Enrico Colli, Aravinda K. Chavalmane, Annamaria Morelli, Mauro Gacci, Luciano Adorini, Mario Maggi, Sandra Filippi

Publikováno v: American Journal of Physiology-Cell Physiology. 294:C1206-C1214

Human bladder contraction mainly depends on Ca2+influx via L-type voltage-gated Ca2+channels and on RhoA/Rho kinase contractile signaling, which is upregulated in overactive bladder (OAB). Elocalcitol is a vitamin D receptor agonist inhibiting RhoA/R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc0f618c68cfb944d3d2f138dd94524
https://doi.org/10.1152/ajpcell.90634.2007

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Differentiating effects of the glucagon-like peptide-1 analogue exendin-4 in a human neuronal cell model

Autor: Fabio Francini, Alessandro Peri, Giovanna Danza, Chiara Di Stefano, Giorgia Luciani, Cristiana Deledda, Roberta Squecco, Francesca Cialdai, Monica Monici, Ilaria Cellai, Susanna Benvenuti, Paola Luciani

Publikováno v: Cellular and molecular life sciences : CMLS. 67(21)

Glucagon-like peptide-1 (GLP-1) is an insulinotropic peptide with neurotrophic properties, as assessed in animal cell models. Exendin-4, a GLP-1 analogue, has been recently approved for the treatment of type 2 diabetes mellitus. The aim of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb0b96364d8e6370b9b7633b919e91d
https://pubmed.ncbi.nlm.nih.gov/20496097

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Skeletal myoblasts overexpressing relaxin improve differentiation and communication of primary murine cardiomyocyte cell cultures

Autor: Giorgia Luciani, Daniele Bani, Fabio Naro, Elisabetta Meacci, Lucia Formigli, Fabio Francini, Josh D. Silvertown, Silvia Nistri, Martina Margheri, Sandra Zecchi Orlandini

Publikováno v: Journal of molecular and cellular cardiology. 47(2)

The possibility that resident myocardial progenitor cells may be re-activated by transplantation of exogenous stem cells into the post-infarcted heart has been suggested as a possible mechanism to explain the heart's functional improvement after stem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6b4fb29983f8bb2b73e629dbf5c0e3
https://pubmed.ncbi.nlm.nih.gov/19465027

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