Organ-specific expression of IGF-I during early development of bony fish as revealed in the tilapia, Oreochromis niloticus , by in situ hybridization and immunohistochemistry: indication for the particular importance of local IGF-I

Autor: Manfred Reinecke, Jean-François Baroiller, Elisabeth Eppler, Natallia Shved, Giorgi Berishvili, Frédéric Clota

Publikováno v: Cell and Tissue Research

The cellular sites of insulin-like growth factor I (IGF-I) synthesis in the early developing tilapia (0-140 days post fertilization, DPF) were investigated. IGF-I mRNA and peptide appeared in liver as early as 4 DPF and in gastro-intestinal epithelia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a55f9783c4cad11410a5e88d7e15d9
http://doc.rero.ch/record/316902/files/441_2005_Article_133.pdf

Environmentally Relevant Concentrations of 17α-Ethinylestradiol (EE2) Interfere With the Growth Hormone (GH)/Insulin-Like Growth Factor (IGF)-I System in Developing Bony Fish

Autor: Giorgi Berishvili, Helmut Segner, Manfred Reinecke, Natallia Shved, Jean-François Baroiller

Publikováno v: Toxicological Sciences
Shved, Natallia; Berishvili, Giorgi; Baroiller, Jean-François; Segner, Helmut; Reinecke, Manfred (2008). Environmentally Relevant Concentrations of 17α-Ethinylestradiol (EE2) Interfere With the Growth Hormone (GH)/Insulin-Like Growth Factor (IGF)-I System in Developing Bony Fish. Toxicological sciences, 106(1), pp. 93-102. Oxford University Press 10.1093/toxsci/kfn150

The aim of this study was to evaluate whether effects of environmental estrogens on fish growth and reproduction may be mediated via modulating the growth hormone (GH)/insulin-like growth factor I (IGF-I) system. To this end, developing male and fema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f475db69eb2ce7e2cc4caa3e3d7497a8
https://doi.org/10.1093/toxsci/kfn150

Growth hormone (GH) treatment acts on the endocrine and autocrine/paracrine GH/IGF-axis and on TNF-α expression in bony fish pituitary and immune organs

Autor: Jean-François Baroiller, Giorgi Berishvili, Elisabeth Eppler, Natallia Shved, Peter Mazel

Publikováno v: Fish and Shellfish Immunology

There exist indications that the growth hormone (GH)/insulin-like growth factor (IGF) axis may play a role in fish immune regulation, and that interactions occur via tumour necrosis factor (TNF)-α at least in mammals, but no systematic data exist on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e46542360d39093e0054f52605343b
https://www.zora.uzh.ch/id/eprint/54332/

Seawater and freshwater challenges affect the insulin-like growth factors IGF-I and IGF-II in liver and osmoregulatory organs of the tilapia

Autor: Jean-François Baroiller, Giorgi Berishvili, Karl Link, Elisabeth Eppler, Natallia Shved, Manfred Reinecke, Helena D'Cotta

Publikováno v: Molecular and Cellular Endocrinology

Contradictory studies suggest IGF-I in fish liver and gills is involved in osmoregulation, but nothing is known about the kidney and intestine's role nor about IGF-II's role in any organ. Tilapia were transferred from freshwater (FW) to seawater (SW)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f137315ebba71ade98d77f7e1cf6ac
http://agritrop.cirad.fr/556388/

Ethinylestradiol differentially interferes with IGF-I in liver and extrahepatic sites during development of male and female bony fish

Autor: Helena D'Cotta, Manfred Reinecke, Natallia Shved, Jean-François Baroiller, Elisabeth Eppler, Giorgi Berishvili, Helmut Segner

Publikováno v: Journal of Endocrinology

Growth and sexual development are closely interlinked in fish; however, no reports exist on potential effects of estrogen on the GH/IGF-I-axis in developing fish. We investigate whether estrogen exposure during early development affects growth and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6da2c3343ac57739287d8610064f27
https://www.zora.uzh.ch/id/eprint/29952/