Adenosine A2A and beta-2 adrenergic receptor agonists: novel selective and synergistic multiple myeloma targets discovered through systematic combination screening.

Autor: Rickles RJ; Zalicus Inc., Cambridge, Massachusetts 02142, USA. rrickles@zalicus.com, Tam WF, Giordano TP 3rd, Pierce LT, Farwell M, McMillin DW, Necheva A, Crowe D, Chen M, Avery W, Kansra V, Nawrocki ST, Carew JS, Giles FJ, Mitsiades CS, Borisy AA, Anderson KC, Lee MS

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2012 Jul; Vol. 11 (7), pp. 1432-42. Date of Electronic Publication: 2012 Apr 03.

Adenosine A2A receptor agonists and PDE inhibitors: a synergistic multitarget mechanism discovered through systematic combination screening in B-cell malignancies.

Autor: Rickles RJ; CombinatoRx Inc., 245 1st St., Cambridge, MA 02142, USA. rrickles@combinatorx.com, Pierce LT, Giordano TP 3rd, Tam WF, McMillin DW, Delmore J, Laubach JP, Borisy AA, Richardson PG, Lee MS

Publikováno v: Blood [Blood] 2010 Jul 29; Vol. 116 (4), pp. 593-602. Date of Electronic Publication: 2010 Apr 09.

Adenosine A2AR in viral immune evasion and therapy: unveiling new avenues for treating COVID-19 and AIDS.

Autor: Atif M; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia. maahmad@ju.edu.sa., Alsrhani A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia., Naz F; Northwestern Polytechnical University, Xian, 710060, China., Ullah S; University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore, Lahore, 54590, Pakistan., Abdalla AE; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia., Ullah MI; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia., Mazhari BBZ; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Qurayyat, 75911, Saudi Arabia., Eltayeb LB; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam Bin AbdulAziz University- Al-Kharj, Riyadh, 11942, Saudi Arabia., Hamad I; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia., Ejaz H; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia. hetariq@ju.edu.sa.

Publikováno v: Molecular biology reports [Mol Biol Rep] 2024 Aug 08; Vol. 51 (1), pp. 894. Date of Electronic Publication: 2024 Aug 08.

Regulatory T Cells Negatively Affect IL-2 Production of Effector T Cells through CD39/Adenosine Pathway in HIV Infection.

Autor: Jenabian, Mohammad-Ali^1,2, Seddiki, Nabila^1,2,3, Yatim, Ahmad^1,2, Carriere, Matthieu^1,2, Hulin, Anne⁴, Younas, Mehwish^1,2, Ghadimi, Elnaz⁵, Kök, Ayrin^1,2, Routy, Jean-Pierre⁶, Tremblay, Alain⁷, Sévigny, Jean⁷, Lelievre, Jean-Daniel^1,2,3,8, Levy, Yves^1,2,3,8 yves.levy@hmn.aphp.fr

Publikováno v: PLoS Pathogens. Apr2013, Vol. 9 Issue 4, Special section p1-11. 11p. 1 Diagram, 5 Graphs.

L-type calcium channels as drug targets in CNS disorders.

Autor: Ortner, Nadine J, Striessnig, Jörg

Publikováno v: Channels (19336950); Jan/Feb2016, Vol. 10 Issue 1, p7-13, 7p