Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Giordano Lesma"'
Autor:
Giordano Lesma, Fiorella Meneghetti, Alessandro Sacchetti, Mattia Stucchi, Alessandra Silvani
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 1383-1389 (2014)
An efficient Ugi three-component reaction of a preformed chiral ketimine derived from isatin with various isonitrile and acid components has been developed. The reactions proceeded smoothly and in a stereocontrolled manner with regard to the new cent
Externí odkaz:
https://doaj.org/article/02a647561ae84b23b7b69946f43b2bc9
Autor:
Francesco Airaghi, Andrea Fiorati, Giordano Lesma, Manuele Musolino, Alessandro Sacchetti, Alessandra Silvani
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 147-154 (2013)
Aiming at restricting the conformational freedom of tryptophan-containing peptide ligands, we designed a THBC (tetrahydro-β-carboline)-DKP (diketopiperazine)-based peptidomimetic scaffold capable of arranging in an unusual α-turn conformation. The
Externí odkaz:
https://doaj.org/article/d8a4593719364517a9a670aa59667958
Publikováno v:
Molecules, Vol 22, Iss 11, p 2016 (2017)
This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates
Externí odkaz:
https://doaj.org/article/9fa68edf422c4fb6999adc32a4995498
Autor:
Claudia Spatti, Carmen Lammi, Giordano Lesma, Jacopo Sgrignani, Giovanni Grazioso, Alessandra Silvani, Anna Arnoldi
Publikováno v:
Journal of Medicinal Chemistry. 62:6163-6174
Proprotein convertase subtilisin/kexin 9 (PCSK9) is responsible for the degradation of the hepatic low-density lipoprotein receptor (LDLR), which in turn regulates the circulating low-density lipoprotein cholesterol (LDL-C) level. For this reason, th
Autor:
Giordano Lesma, Alessandra Silvani, Stefano Gazzotti, Hermes Farina, Simona Alessandra Todisco, Claudia Picozzi, Marco Aldo Ortenzi
Publikováno v:
European Polymer Journal. 114:369-379
PLA-based materials with eugenol moieties covalently bonded to the macromolecular chains were synthesized for potential application in bioactive food packaging. The synthetic strategy relies on the exploitation of O-Carboxyanhydrides (OCAs) as versat
Autor:
Riccardo Rampazzo, Alessandra Silvani, Daniele Bussini, Giordano Lesma, Stefano Gazzotti, Minna Hakkarainen, Hermes Farina, Marco Aldo Ortenzi
Publikováno v:
Composites Science and Technology. 171:94-102
One-pot in situ polymerization approach was explored for the preparation of polylactide (PLA)-cellulose nano-fibril (CNF) bio-nanocomposites. CNF were first prepared through enzymatic and mechanica ...
Publikováno v:
RSC Advances. 8:34903-34910
A multicomponent Ugi reaction involving isatin, isocyanide and β-amino acid components has been developed. The reactions proceeded smoothly to give β-lactam-containing 3,3-disubstituted oxindoles in only one step and generally high yields. When chi
Autor:
Hermes Farina, Alessandra Silvani, Luciano Piergiovanni, Giordano Lesma, Stefano Gazzotti, Riccardo Rampazzo, Marco Aldo Ortenzi
Publikováno v:
European Polymer Journal. 94:173-184
The in situ polymerization of l -lactide in the presence of various amounts of cellulose nanocrystals (CNC) is described. CNC was prepared efficiently by acidic hydrolysis of cotton linters. Molecular weight, morphology, thermal, mechanical and cryst
Autor:
Sandra Rondinini, Alessandro Miani, Alberto Vertova, Luigi Falciola, Alessandro Minguzzi, Giordano Lesma, Marco Aldo Ortenzi
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 16
Issue 22
International Journal of Environmental Research and Public Health, Vol 16, Iss 22, p 4582 (2019)
Volume 16
Issue 22
International Journal of Environmental Research and Public Health, Vol 16, Iss 22, p 4582 (2019)
Chlorine dioxide (ClO2) has been widely used as a disinfectant in drinking water in the past but its effects on water pipes have not been investigated deeply, mainly due to the difficult experimental set-up required to simulate real-life water pipe c
Publikováno v:
Synlett. 27:2831-2835
A one-pot, three-component reaction has been developed and successfully employed for the synthesis of biologically relevant, highly functionalized spirooxindole-fused 3-thiazoline derivatives. Starting from ammonia, three mercapto carbonyl components