Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Giora Volpert"'
Autor:
Iris D. Zelnik, Giora Volpert, Leena E. Viiri, Dimple Kauhanen, Tamar Arazi, Katriina Aalto-Setälä, Reijo Laaksonen, Anthony H. Futerman
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 10, Pp 1341-1346 (2020)
The backbone of all sphingolipids (SLs) is a sphingoid long-chain base (LCB) to which a fatty acid is N-acylated. Considerable variability exists in the chain length and degree of saturation of both of these hydrophobic chains, and recent work has im
Externí odkaz:
https://doaj.org/article/304856de0b1d4bf49da64840fc81f255
Autor:
Dimple Kauhanen, Iris D. Zelnik, Tamar Arazi, Anthony H. Futerman, Reijo Laaksonen, Katriina Aalto-Setälä, Leena E. Viiri, Giora Volpert
Publikováno v:
J Lipid Res
Journal of Lipid Research, Vol 61, Iss 10, Pp 1341-1346 (2020)
Journal of Lipid Research, Vol 61, Iss 10, Pp 1341-1346 (2020)
The backbone of all sphingolipids (SLs) is a sphingoid long-chain base (LCB) to which a fatty acid is N-acylated. Considerable variability exists in the chain length and degree of saturation of both of these hydrophobic chains, and recent work has im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bab769d820b01d98f1c623f106c0a5
https://trepo.tuni.fi/handle/10024/127940
https://trepo.tuni.fi/handle/10024/127940
Autor:
Rotem Tidhar, Alfred H. Merrill, Shifra Ben-Dor, Anthony H. Futerman, Giora Volpert, Samuel Kelly, Iris D. Zelnik
Publikováno v:
Journal of Biological Chemistry. 293:9912-9921
Lipids display large structural complexity, with ∼40,000 different lipids identified to date, ∼4000 of which are sphingolipids. A critical factor determining the biological activities of the sphingolipid, ceramide, and of more complex sphingolipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89afc3a049253389215606688c9b3f56
https://doi.org/10.1074/jbc.ra118.001936
https://doi.org/10.1074/jbc.ra118.001936
Autor:
Anthony H. Futerman, Sun Hye Shin, Yael Pewzner-Jung, Ye Ryung Kim, Yong-Moon Lee, Sun Hee Sung, Kyong Oh Shin, Younghay Lee, Giora Volpert, Joo Won Park, Woo Jae Park, Jung Hyuck Ahn, So Yeon Kim
Publikováno v:
Journal of Cellular and Molecular Medicine
Ceramides mediate crucial cellular processes including cell death and inflammation and have recently been implicated in inflammatory bowel disease. Ceramides consist of a sphingoid long‐chain base to which fatty acids of various length can be attac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494c89f24ba2d36f19251c0134f49a1b
https://doi.org/10.1111/jcmm.13267
https://doi.org/10.1111/jcmm.13267
Autor:
Hila Zigdon, Giora Volpert, Helena Sabanay, Tamar Farfel-Becker, Anna Meshcheriakova, Anthony H. Futerman
Publikováno v:
FEBS Letters. 591:774-783
In the lysosomal storage disorder Gaucher disease (GD), glucosylceramide (GlcCer) accumulates due to the defective activity of glucocerebrosidase. A subset of GD patients develops neuropathology. We now show mislocalization of Limp2-positive puncta a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710b2d6adcfb523cc946c615edc70c9f
https://doi.org/10.1002/1873-3468.12591
https://doi.org/10.1002/1873-3468.12591
Autor:
Andrzej Sliwa-Gonzalez, Anthony H. Futerman, Maya Schuldiner, Márton Megyeri, A. Galih Haribowo, Howard Riezman, Giora Volpert, Yves Barral, Auxiliadora Aguilera-Romero, Rupali Prasad
Publikováno v:
Journal of Cell Science, 132 (12)
Journal of Cell Science, Vol. 132, No jcs228411 (2019)
Journal of Cell Science
Journal of Cell Science, Vol. 132, No jcs228411 (2019)
Journal of Cell Science
LAG1 was the first longevity assurance gene discovered in Saccharomyces cerevisiae. The Lag1 protein is a ceramide synthase and its homolog, Lac1, has a similar enzymatic function but no role in aging. Lag1 and Lac1 lie in an enzymatic branch point o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b53f69476bf06ae82ffb02288b00aad
https://hdl.handle.net/20.500.11850/351727
https://hdl.handle.net/20.500.11850/351727
Autor:
Giora Volpert, Natalia Santos Ferreira, Samuel Kelly, Nils J. Færgeman, Hanne Engelsby, Ditte Neess, Alfred H. Merrill, Anthony H. Futerman
Publikováno v:
Ferreira, N S, Engelsby, H, Neess, D, Kelly, S L, Volpert, G, Merrill, A H, Futerman, A H & Færgeman, N J 2017, ' Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein ', Journal of Biological Chemistry, vol. 292, no. 18, pp. 7588-7597 . https://doi.org/10.1074/jbc.M117.785345
Ceramide and more complex sphingolipids constitute a diverse group of lipids that serve important roles as structural entities of biological membranes and as regulators of cellular growth, differentiation, and development. Thus, ceramides are vital p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836daf4a85ad85fba0646569a5208bc3
https://findresearcher.sdu.dk:8443/ws/files/125851453/Regulation_of_very_long_acyl_chain_ceramide_synthesis_by_acyl_CoA_binding_protein.pdf
https://findresearcher.sdu.dk:8443/ws/files/125851453/Regulation_of_very_long_acyl_chain_ceramide_synthesis_by_acyl_CoA_binding_protein.pdf
Autor:
Alexandra Chalastanis, Anthony H. Futerman, Giora Volpert, Andrea E. Calvert, Fotini M. Kouri, Alexander H. Stegh, Janina P. Luciano, Samuel A. Jensen, Yongfei Wu, Lisa A. Hurley
Publikováno v:
Proceedings of the National Academy of Sciences. 111:5682-5687
Therapy resistance is a major limitation to the successful treatment of cancer. Here, we identify Bcl2-like 13 (Bcl2L13), an atypical member of the Bcl-2 family, as a therapy susceptibility gene with elevated expression in solid and blood cancers, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbf648b1e2e593aa1a1da9cc018a94f
https://doi.org/10.1073/pnas.1316700111
https://doi.org/10.1073/pnas.1316700111