Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Giora Simchen"'
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002083 (2011)
Accurate segregation of homologous chromosomes of different parental origin (homologs) during the first division of meiosis (meiosis I) requires inter-homolog crossovers (COs). These are produced at the end of meiosis I prophase, when recombination i
Externí odkaz:
https://doaj.org/article/6e0350ee2700402891a8e33f67ad2175
Autor:
Alon Goren, Giora Simchen, Eitan Fibach, Piroska E Szabo, Keiji Tanimoto, Lyubomira Chakalova, Gerd P Pfeifer, Peter J Fraser, James D Engel, Howard Cedar
Publikováno v:
PLoS ONE, Vol 1, p e46 (2006)
Expression patterns in the globin gene cluster are subject to developmental regulation in vivo. While the gamma(A) and gamma(G) genes are expressed in fetal liver, both are silenced in adult erythrocytes. In order to decipher the role of DNA methylat
Externí odkaz:
https://doaj.org/article/891905ef65c146f0b7b387e5dbf7dc55
Autor:
Giora Ben-Ari, Drora Zenvirth, Amir Sherman, Lior David, Michael Klutstein, Uri Lavi, Jossi Hillel, Giora Simchen
Publikováno v:
PLoS Genetics, Vol 2, Iss 11, p e195 (2006)
Quantitative traits are conditioned by several genetic determinants. Since such genes influence many important complex traits in various organisms, the identification of quantitative trait loci (QTLs) is of major interest, but still encounters seriou
Externí odkaz:
https://doaj.org/article/0b1cce38a5834942a3e73baa1f12674c
Publikováno v:
Current Genetics. 67:799-806
Mutations in diploid budding yeast occur in meiosis at higher frequencies than in cells grown vegetatively. Such meiotic mutations are thought to result from the repair of double-strand breaks (DSBs) in meiosis, during the process of recombination. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b14c16759630105f04214bec3cedba
https://doi.org/10.1007/s00294-021-01189-w
https://doi.org/10.1007/s00294-021-01189-w
Autor:
Keren Zion, Osama Mansour, Renana Elgrabli, Ayelet Arbel-Eden, Giora Simchen, Drora Zenvirth, Liat Morciano
Publikováno v:
Current genetics. 66(3)
Mutations in budding yeast occur in meiosis at higher frequencies than in cells grown vegetatively. In contrast to mutations that occur in somatic cells, meiotic mutations have a special, long-range impact on evolution, because they are transferred t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd43d534d574e72fc263fbdf76d89ee5
https://pubmed.ncbi.nlm.nih.gov/31932974
https://pubmed.ncbi.nlm.nih.gov/31932974
Autor:
Ayelet Arbel-Eden, Giora Simchen
Publikováno v:
BioEssays. 41:1800235
Diploid germ cells produce haploid gametes through meiosis, a unique type of cell division. Independent reassortment of parental chromosomes and their recombination leads to ample genetic variability among the gametes. Importantly, new mutations also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f6f78fd3f55ec49df38ce40226f3fe
https://doi.org/10.1002/bies.201800235
https://doi.org/10.1002/bies.201800235
Autor:
Giora Simchen, Ayelet Arbel-Eden
Publikováno v:
BioEssays. 41:1970041
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f37aaaf05b9916608cfd934237f98f
https://doi.org/10.1002/bies.201970041
https://doi.org/10.1002/bies.201970041
Autor:
Eléanor Rachi, Giora Simchen, Hagit Masika, Oxana Printzental, Ayelet Arbel-Eden, Daphna Joseph-Strauss
Publikováno v:
G3: Genes|Genomes|Genetics
Trans-lesion DNA polymerases (TLSPs) enable bypass of DNA lesions during replication and are also induced under stress conditions. Being only weakly dependent on their template during replication, TLSPs introduce mutations into DNA. The low processiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4481ef2b2e3809d30de18f9236615b76
https://doi.org/10.1534/g3.113.005603
https://doi.org/10.1534/g3.113.005603
Autor:
Giora Simchen
Publikováno v:
BioEssays. 31:169-177
In budding yeast, commitment to meiosis is attained when meiotic cells cannot return to the mitotic cell cycle even if the triggering cue (nutrients deprivation) is withdrawn. Commitment is arrived at gradually, and different aspects of meiosis may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5b2bc58c12ef0414adf990ffb7b228
https://doi.org/10.1002/bies.200800124
https://doi.org/10.1002/bies.200800124
Autor:
Oren Gordon, Giora Simchen, Aleksander Benjak, Michael Knop, Ernst H. K. Stelzer, Christof Taxis, Philipp J. Keller
Publikováno v:
The EMBO Journal. 25:3856-3868
Nud1p, a protein homologous to the mammalian centrosome and midbody component Centriolin, is a component of the budding yeast spindle pole body (SPB), with roles in anchorage of microtubules and regulation of the mitotic exit network during vegetativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef71da96543c4f272413d2d8724db29b
https://doi.org/10.1038/sj.emboj.7601254
https://doi.org/10.1038/sj.emboj.7601254