Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Giora, Landesberg"'
Autor:
Tural Alekberli, Braha Lea Ohana, Hai Zemmour, Rudy Khader, Ruth Shemer, Yuval Dor, Giora Landesberg
Publikováno v:
Journal of International Medical Research, Vol 52 (2024)
Objective To present a novel method that uses an epigenetic fingerprint to measure changes in plasma concentrations of cardiac-specific cell-free DNA (CS-cfDNA) as a marker of myocardial cell death. Methods This prospective, analytic, observational c
Externí odkaz:
https://doaj.org/article/0f731a25fa124e3db2e75cbe2faf3a17
Autor:
Joshua Moss, Judith Magenheim, Daniel Neiman, Hai Zemmour, Netanel Loyfer, Amit Korach, Yaacov Samet, Myriam Maoz, Henrik Druid, Peter Arner, Keng-Yeh Fu, Endre Kiss, Kirsty L. Spalding, Giora Landesberg, Aviad Zick, Albert Grinshpun, A. M. James Shapiro, Markus Grompe, Avigail Dreazan Wittenberg, Benjamin Glaser, Ruth Shemer, Tommy Kaplan, Yuval Dor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The methylation status of circulating cell-free DNA (cfDNA) can be informative about recent cell death events. Here the authors present an approach to determine the tissue origins of cfDNA, using a reference methylation atlas of 25 human tissues and
Externí odkaz:
https://doaj.org/article/841a0167145749b69b07423fda860202
Autor:
Hai Zemmour, David Planer, Judith Magenheim, Joshua Moss, Daniel Neiman, Dan Gilon, Amit Korach, Benjamin Glaser, Ruth Shemer, Giora Landesberg, Yuval Dor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The detection of cardiomyocyte death is a critical aspect in the diagnosis and monitoring of heart diseases. Here the authors show that cardiomyocyte-specific methylation patterns of circulating cell-free DNA may serve as a biomarker of cardiac cell
Externí odkaz:
https://doaj.org/article/3d19d38519134934b5a7135c3d3d3ad2
Autor:
Ayelet Peretz, Netanel Loyfer, Sheina Piyanzin, Bracha Lea Ochana, Daniel Neiman, Judith Magenheim, Agnes Klochendler, Zeina Drawshy, Ilana Fox-Fisher, Ori Fridlich, Joshua Moss, Daniel Cohen, Hai Zemmour, Gordon Cann, Joerg Bredno, Oliver Venn, Batia Avni, Tural Alekberli, Yaacov Samet, Amit Korach, Ori Wald, Vladimir Yutkin, Uzi Izhar, Nir Pillar, Markus Grompe, Zvi Fridlender, Ariel Rokach, David Planer, Giora Landesberg, Benjamin Glaser, Ruth Shemer, Tommy Kaplan, Yuval Dor
Publikováno v:
Med. 4:263-281.e4
Autor:
Yuval Dor, Daniel Neiman, Hai Zemmour, Ruth Shemer, Joshua Moss, Benjamin Glaser, Amit Korach, Giora Landesberg, Judith Magenheim, Dan Gilon, David Planer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
Detection of cardiomyocyte death is crucial for the diagnosis and treatment of heart disease. Here we use comparative methylome analysis to identify genomic loci that are unmethylated specifically in cardiomyocytes, and develop these as biomarkers to
Autor:
Giora Landesberg, Maurizio Cecconi, Antoine Vieillard-Baron, Filippo Sanfilippo, Antonio Arcadipane, N. Fletcher, Carlos Corredor
Publikováno v:
British Journal of Anaesthesia. 119:583-594
Background Myocardial dysfunction may contribute to circulatory failure in sepsis. There is growing evidence of an association between left ventricular diastolic dysfunction (LVDD) and mortality in septic patients. Utilizing echocardiography, we know
Publikováno v:
AA practice. 13(4)
We present a patient who was admitted for carotid endarterectomy due to tight carotid stenosis and recent amaurosis fugax. His medical history included significant coronary artery disease with stable angina pectoris, hypertension with wide pulse pres
Autor:
Ruth Shemer, Daniel Neiman, Hai Zemmour, Markus Grompe, Kim M. Olthoff, Benjamin Glaser, Judith Magenheim, Ofri Abraham, Sheina Piyanzin, Giora Landesberg, Roni Lehmann-Werman, Joshua Moss, Bao Li Loza, Ilana Fox, Talya Dor, Yuval Dor, Abraham Shaked
Publikováno v:
JCI Insight
Liver damage is typically inferred from serum measurements of cytoplasmic liver enzymes. DNA molecules released from dying hepatocytes are an alternative biomarker, unexplored so far, potentially allowing for quantitative assessment of liver cell dea
Autor:
Phillip D. Levin, Milena Georgieva, Charles Weissman, Giora Landesberg, Vivian Barak, Allan S. Jaffe, Dan Gilon, Sergey Goodman, Charles L. Sprung
Publikováno v:
Chest. 148:93-102
BACKGROUND In vitro studies suggested that circulating inflammatory cytokines cause septic myocardial dysfunction. However, no in vivo clinical study has investigated whether serum inflammatory cytokine concentrations correlate with septic myocardial
Autor:
Giora Landesberg, Charles Weissman, Phillip D. Levin, Allan S. Jaffe, Charles L. Sprung, Abed Abu-Baih, Dan Gilon, Sergey Goodman, Ronen Beeri, Amir Landesberg
Publikováno v:
Critical Care Medicine. 42:790-800
Serum troponin concentrations predict mortality in almost every clinical setting they have been examined, including sepsis. However, the causes for troponin elevations in sepsis are poorly understood. We hypothesized that detailed investigation of my