Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gioia Cherubini"'
Autor:
Enrique Miranda, Hector Maya Pineda, Daniel Öberg, Gioia Cherubini, Zita Garate, Nick R Lemoine, Gunnel Halldén
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46617 (2012)
Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies. The replication-selective mutants AdΔΔ and dl922-947, defective in pRb-binding, have bee
Externí odkaz:
https://doaj.org/article/a3cecce52b2349eab6e0859e5b5b5795
Publikováno v:
Virus Research. 130:71-84
One problem encountered in the use of adenoviral vectors for gene therapy is their toxicity. Although many studies have analyzed this question in vivo, few researches have investigated adenovirus vector effects at the cellular level using a large-sca
Publikováno v:
Oncotarget
Adenovirus-mediated sensitization of cancer cells to cytotoxic drugs depends on simultaneous interactions of early viral genes with cell death and survival pathways. It is unclear what cellular factors mediate these interactions in the presence of DN
Autor:
Benedetto Sacchetti, Gioia Cherubini, Désirée Bonci, Cesare Peschle, S. Di Cesare, Paolo Bianco, Isabella Saggio, Mara Riminucci, Stefania Piersanti, Alessia Funari
Publikováno v:
Calcified tissue international 78 (2006): 372–384.
info:cnr-pdr/source/autori:Piersanti S, Sacchetti B, Funari A, Di Cesare S, Bonci D, Cherubini G, Peschle C, Riminucci M, Bianco P, Saggio I ./titolo:Lentiviral transduction of human postnatal skeletal (stromal, mesenchymal) stem cells: in vivo transplantation and gene silencing./doi:/rivista:Calcified tissue international/anno:2006/pagina_da:372/pagina_a:384/intervallo_pagine:372–384/volume:78
info:cnr-pdr/source/autori:Piersanti S, Sacchetti B, Funari A, Di Cesare S, Bonci D, Cherubini G, Peschle C, Riminucci M, Bianco P, Saggio I ./titolo:Lentiviral transduction of human postnatal skeletal (stromal, mesenchymal) stem cells: in vivo transplantation and gene silencing./doi:/rivista:Calcified tissue international/anno:2006/pagina_da:372/pagina_a:384/intervallo_pagine:372–384/volume:78
Systems for gene transfer and silencing in human skeletal stem cells (hSSCs, also stromal or mesenchymal stem cells) are important for addressing critical issues in basic hSSC and skeletal biology and for developing gene therapy strategies for treatm
Publikováno v:
American Journal of PharmacoGenomics. 4:345-356
Given the biological complexity of viral infections, the variability of the host response, and the safety concerns related to viral-mediated gene transfer, recent studies have made use of DNA mircoarrays to integrate multi-layered experimental approa
Autor:
Laure Franqueville, Yuri Martina, Gioia Cherubini, Stefania Piersanti, Isabella Saggio, Cristina Maria Failla, Enrico Cundari, Pierre Boulanger, Barbara Salone
Publikováno v:
Journal of Virology. 77:13448-13454
Many adenovirus serotypes enter cells by high-affinity binding to the coxsackievirus-adenovirus receptor (CAR) and integrin-mediated internalization. In the present study, we analyzed the possible receptor function of α3β1 for adenovirus serotype 5
Autor:
Nicholas R. Lemoine, C Kallin, A Mozetic, Heike Müller, Gioia Cherubini, K Hammaren-Busch, Gunnel Halldén
Publikováno v:
Gene therapy. 18(12)
Pancreatic adenocarcinomas are aggressive and frequently develop resistance to all current therapies. Replication-selective adenoviruses can overcome resistance to chemotherapeutics through their sensitizing effects on drug-induced cell killing. We p
Autor:
Massimo Bogliolo, Karim Benihoud, Paola Caruso, Isabella Saggio, Filippo Rosselli, Romina Burla, Valeria Naim, Enrico Cundari, Gioia Cherubini
Publikováno v:
Nucleic acids research (2011).
info:cnr-pdr/source/autori:Cherubini G, Naim V, Caruso P, Burla R, Bogliolo M, Cundari E, Benihoud K, Saggio I, Rosselli F./titolo:The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination/doi:/rivista:Nucleic acids research/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nucleic Acids Research
Nucleic Acids Research; Vol 39
info:cnr-pdr/source/autori:Cherubini G, Naim V, Caruso P, Burla R, Bogliolo M, Cundari E, Benihoud K, Saggio I, Rosselli F./titolo:The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination/doi:/rivista:Nucleic acids research/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nucleic Acids Research
Nucleic Acids Research; Vol 39
Deciphering the crosstalk between a host cell and a virus during infection is important not only to better define viral biology but also to improve our understanding of cellular processes. We identified the FANC pathway as a helper of viral replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f8d74dd9db32227ef219fb2c167287
https://publications.cnr.it/doc/11843
https://publications.cnr.it/doc/11843
Autor:
Gioia Cherubini, Cristina Remoli, Romina Burla, Isabella Saggio, Yuri Martina, Paola Caruso, Stefania Piersanti
Publikováno v:
Virology (N.Y.N.Y., Print) 385 (2009): 343–350.
info:cnr-pdr/source/autori:Caruso P, Burla R, Piersanti S, Cherubini G, Remoli C, Martina Y, Saggio I./titolo:Prion expression is activated by Adenovirus 5 infection and affects the adenoviral cycle in human cells./doi:/rivista:Virology (N.Y.N.Y., Print)/anno:2009/pagina_da:343/pagina_a:350/intervallo_pagine:343–350/volume:385
info:cnr-pdr/source/autori:Caruso P, Burla R, Piersanti S, Cherubini G, Remoli C, Martina Y, Saggio I./titolo:Prion expression is activated by Adenovirus 5 infection and affects the adenoviral cycle in human cells./doi:/rivista:Virology (N.Y.N.Y., Print)/anno:2009/pagina_da:343/pagina_a:350/intervallo_pagine:343–350/volume:385
The prion protein is a cell surface glycoprotein whose physiological role remains elusive, while its implication in transmissible spongiform encephalopathies (TSEs) has been demonstrated. Multiple interactions between the prion protein and viruses ha
Autor:
Ottaviano Serlupi-Crescenzi, Paolo Carminati, Stefania Rossi, Isabella Saggio, Brunilde Arseni, Rita De Santis, Silvia Campo, Barbara Salone, Gioia Cherubini
Publikováno v:
Cytokine. 31(5)
Interleukin-6 (IL-6) plays a central role in the pathogenesis of several autoimmune and inflammatory diseases as well as B-cell lymphoproliferative disorders. This work describes the effects of the recombinant or adenovirally-delivered IL-6 superanta