Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gints Smits"'
Autor:
Juris Pelss, Gints Smits
Publikováno v:
ACS Omega, Vol 5, Iss 21, Pp 12568-12572 (2020)
Externí odkaz:
https://doaj.org/article/aa17ac495041497cae1346d6d9bb0e7a
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05e91404e5831ba90d27b9205ca73c7
https://doi.org/10.1002/ejoc.202201217
https://doi.org/10.1002/ejoc.202201217
Publikováno v:
ACS omega. 7(34)
Total syntheses of three pyrrolo[1,4]benzodiazepine anticancer antibiotic family members oxo-prothracarcin, oxo-tomaymycin, and boseongazepine B are described. The total syntheses feature late-stage stereoselective olefination employing modified Juli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598b08963af0ae61061d38ea4ce7efb9
https://pubmed.ncbi.nlm.nih.gov/36061714
https://pubmed.ncbi.nlm.nih.gov/36061714
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:572-577
A comprehensive screening of known methods for the synthesis of coumarins was performed in order to obtain a new type of pyrrolobenzodiazepine–coumarin hybrids. A Pechmann condensation turned out to be the method of choice for successful synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e6644cdc4c1bffb001db9f1fd02f92
https://doi.org/10.1007/s10593-020-02702-8
https://doi.org/10.1007/s10593-020-02702-8
Autor:
Gints Smits, Juris Pelss
Publikováno v:
ACS Omega, Vol 5, Iss 21, Pp 12568-12572 (2020)
ACS Omega
ACS Omega
The first total synthesis of flavesines G and J, natural products exhibiting antiviral activity against hepatitis B virus, is described. A robust, protecting-group-free route starting from commercially available natural product 9-azajulolidine allowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4390d71c2af602c126accd1b6ee0d666
https://doaj.org/article/aa17ac495041497cae1346d6d9bb0e7a
https://doaj.org/article/aa17ac495041497cae1346d6d9bb0e7a
Autor:
Gints Smits, Ronalds Zemribo
Publikováno v:
Organic & Biomolecular Chemistry. 18:4566-4568
A synthetic approach towards the core of a structurally unique cytotoxic indole alkaloid eleganine A has been accomplished for the first time. The synthesis features a stereoselective Ireland-Claisen rearrangement as the key step, enabling the instal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae93ee96a64a3d32bcde254802488ef
https://doi.org/10.1039/d0ob00939c
https://doi.org/10.1039/d0ob00939c
Publikováno v:
Organometallics. 38:3939-3947
Chiral cyclopentadienyl (Cpx) group 9 metal complexes have become versatile catalysts for a variety of efficient enantioselective C–H functionalizations. Atropchiral binaphthyl-derived Cpx ligands having tuning options at the 3,3′-positions prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8548e9f96ca4204f522de2e3c75a9e
https://doi.org/10.1021/acs.organomet.9b00365
https://doi.org/10.1021/acs.organomet.9b00365
Publikováno v:
Natural Product Research. 35:440-446
The total synthesis of both the double bond isomers of indolizine alkaloid 8-deoxypumiliotoxin 193H has been accomplished. Both the double bond isomers Z-4 and E-4 induced convulsions and inhibited...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30af1fbc099cb9bf6e45fab08280892e
https://doi.org/10.1080/14786419.2019.1636244
https://doi.org/10.1080/14786419.2019.1636244
Publikováno v:
The Journal of organic chemistry. 86(9)
The stereoselective total synthesis of the proposed structure of a potent serotonin 5-HT1A receptor agonist uncarialin A (1) is described. By employing the readily available meroquinene tert-butyl ester as the chiral synthon, the target structure has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cab5f4523cc63bdc173c31472585b4d
https://pubmed.ncbi.nlm.nih.gov/33881855
https://pubmed.ncbi.nlm.nih.gov/33881855
Publikováno v:
Medicinal research reviewsREFERENCES. 42(1)
The isolation of the antitumor antibiotic anthramycin in the 1960s prompted extensive research into pyrrolo[1,4]benzodiazepines (PBD) as potential therapeutics for the treatment of cancers. Since then, nearly 60 PBD natural products have been isolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e664dd828cfa08a5b484a9f2ecc818
https://pubmed.ncbi.nlm.nih.gov/33846985
https://pubmed.ncbi.nlm.nih.gov/33846985