Výsledky vyhledávání - "Gintautas Zvirblis"

Akademický článek

Human granulocyte-colony stimulating factor (G-CSF)/stem cell factor (SCF) fusion proteins: design, characterization and activity

Autor: Gitana Mickiene, Indrė Dalgėdienė, Gintautas Zvirblis, Zilvinas Dapkunas, Ieva Plikusiene, Ernesta Buzavaite-Verteliene, Zigmas Balevičius, Audronė Rukšėnaitė, Milda Pleckaityte

Publikováno v: PeerJ, Vol 8, p e9788 (2020)

Background Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are well-characterized vital hematopoietic growth factors that regulate hematopoiesis. G-CSF and SCF synergistically exhibit a stimulatory effect on hematopoietic pro

Externí odkaz: https://doaj.org/article/017b6f6e86514bed8846eac19633e780

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Akademický článek

Generation of dimeric single-chain antibodies neutralizing the cytolytic activity of vaginolysin

Autor: Zilvinas Dapkunas, Aurimas Baranauskas, Gitana Mickiene, Milda Pleckaityte, Gintautas Zvirblis

Publikováno v: Electronic Journal of Biotechnology, Vol 28, Iss C, Pp 52-57 (2017)

Background: Gardnerella vaginalis is a bacterial vaginosis (BV)-associated vaginal bacterium that produces the toxin vaginolysin (VLY). VLY is a pore-forming toxin that is suggested to be the main virulence factor of G. vaginalis. The high recurrence

Externí odkaz: https://doaj.org/article/c358b51601e844c0951b198d50eda96f

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Akademický článek

Influenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting.

Autor: Geoffrey P Chase, Marie-Anne Rameix-Welti, Aurelija Zvirbliene, Gintautas Zvirblis, Veronika Götz, Thorsten Wolff, Nadia Naffakh, Martin Schwemmle

Publikováno v: PLoS Pathogens, Vol 7, Iss 9, p e1002187 (2011)

In contrast to most RNA viruses, influenza viruses replicate their genome in the nucleus of infected cells. As a result, newly-synthesized vRNA genomes, in the form of viral ribonucleoprotein complexes (vRNPs), must be exported to the cytoplasm for p

Externí odkaz: https://doaj.org/article/68310bef0de84cffa627d438a764ca72

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Immunological comparison of recombinant shrimp allergen Pen m 4, produced in Pichia pastoris and Escherichia coli

Autor: Juta Rainyte, Gintautas Zvirblis, Mindaugas Zaveckas, Indre Kucinskaite-Kodze, Laimis Silimavicius, Rasa Petraityte-Burneikiene

Publikováno v: Journal of Biotechnology. 369:1-13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f9292f9b91ce8ab5911d7e60d027119
https://doi.org/10.1016/j.jbiotec.2023.05.002

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Human granulocyte-colony stimulating factor (G-CSF)/stem cell factor (SCF) fusion proteins: design, characterization and activity

Autor: Ernesta Buzavaite-Verteliene, Zilvinas Dapkunas, Gitana Mickiene, Zigmas Balevičius, Milda Pleckaityte, Ieva Plikusiene, Audronė Rukšėnaitė, Indrė Dalgėdienė, Gintautas Zvirblis

Publikováno v: PeerJ, London : PeerJ Inc., 2020, vol. 8, art. no. c9788, p. 1-23
PeerJ
PeerJ, Vol 8, p e9788 (2020)

BackgroundStem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are well-characterized vital hematopoietic growth factors that regulate hematopoiesis. G-CSF and SCF synergistically exhibit a stimulatory effect on hematopoietic prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddf1ce1b8800b2cabdc40d965e10405
https://repository.vu.lt/VU:ELABAPDB68766837&prefLang=en_US

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Evaluation of affinity sensor response kinetics towards dimeric ligands linked with spacers of different rigidity: Immobilized recombinant granulocyte colony-stimulating factor based synthetic receptor binding with genetically engineered dimeric analyte derivatives

Autor: Saulius Balevicius, Ieva Plikusiene, Gintautas Zvirblis, Gitana Mickiene, Arunas Ramanavicius, Zigmas Balevicius, Alla Tereshchenko, Julian Talbot, Arunas Stirke, Almira Ramanaviciene, Linas Tamosaitis

Publikováno v: Biosensors and Bioelectronics
Biosensors and Bioelectronics, Elsevier, 2020, 156, pp.112112. ⟨10.1016/j.bios.2020.112112⟩

The modelling of protein-protein binding kinetics is important for the development of affinity-sensors and the prediction of signaling protein based drug efficiency. Therefore, in this research we have evaluated the binding kinetics of several geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c5b7e8723895d074abf1c6a2aa5ef9
https://pubmed.ncbi.nlm.nih.gov/32174551

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New broadly reactive neutralizing antibodies against hepatitis B virus surface antigen

Autor: Aurelija Zvirbliene, Pia L. Seiz, Gitana Mickiene, Milda Zilnyte, Aiste Bulavaite, Indre Kucinskaite-Kodze, Gintautas Zvirblis, Milda Pleckaityte, Corinna M. Bremer, Dieter Glebe, Kestutis Sasnauskas

Publikováno v: ORCID
Microsoft Academic Graph
Europe PubMed Central
Elsevier
Aurelija Zvirbliene
Virus Research

Hepatitis B virus (HBV) surface antigen (HBsAg) is considered to be the most important target for the diagnosis and immune prophylaxis of HBV infection. HBsAg-specific monoclonal antibodies (MAbs) are extensively used for studying the complex structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f938cdf0c2d3004c2b7171e20fa6ebd
https://doi.org/10.1016/j.virusres.2015.10.024

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Generation of dimeric single-chain antibodies neutralizing the cytolytic activity of vaginolysin

Autor: Gintautas Zvirblis, Gitana Mickiene, Milda Pleckaityte, Aurimas Baranauskas, Zilvinas Dapkunas

Publikováno v: Electronic journal of biotechnology, Valparaíso : Pontificia Universidad Católica de Valparaíso, 2017, Vol. 28, p. 52-57
Electronic Journal of Biotechnology, Vol 28, Iss C, Pp 52-57 (2017)

Background: Gardnerella vaginalis is a bacterial vaginosis-associated vaginal bacterium, which produces toxin vaginolysin (VLY). VLY is a pore-forming toxin suggested to be the main virulence factor of G. vaginalis. The high recurrence rate of BV and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e2b622e86b8ed39af176080128cfbd
https://repository.vu.lt/VU:ELABAPDB24121510&prefLang=en_US

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Akademický článek

Monoclonal antibodies against the newly identified allergen β-enolase from common carp (Cyprinus carpio)

Autor: Aistė Sližienė, Milda Plečkaitytė, Mindaugas Zaveckas, Karolina Juškaitė, Vytautas Rudokas, Gintautas Žvirblis, Aurelija Žvirblienė

Publikováno v: Food and Agricultural Immunology, Vol 33, Iss 1, Pp 129-149 (2022)

β-enolase is a heat-labile fish allergen identified in different fish species. In this study, β-enolase gene was cloned from common carp muscle tissue and the target protein was expressed as a fusion with maltose binding protein (MBP-Eno) in E. col

Externí odkaz: https://doaj.org/article/3bd31b7e96ac4105ad4cf99f498af14a

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