Possible Interaction between Dabigatran and Ranolazine in Patients with Renal Failure

Autor: Gintautas Gumbrevičius, Gytė Damulevičienė, Vaidotas Galaunė, Milda Gumbrevičiūtė

Publikováno v: Medicina, Vol 56, Iss 1, p 13 (2019)

Dabigatran etexilate is a direct oral anticoagulant (thrombin inhibitor) used for the prevention of stroke and systemic thromboembolic events in patients with permanent atrial fibrillation; prevention of venous thromboembolic events and deep veins th

Externí odkaz: https://doaj.org/article/55478222eb6e4288a4a763f001303883

The Glomerular Filtration Rate Estimators in the Pharmacokinetic Modelling in Acute Kidney Injury: An Observational Study

Autor: Vaidotas Galaune, Astra Vitkauskiene, Silvijus Abramavicius, Romaldas Mačiulaitis, Gintautas Gumbrevičius, Agile Tunaityte, Aurelija Radzeviciene

Publikováno v: Antibiotics
Volume 10
Issue 2
Antibiotics, Vol 10, Iss 158, p 158 (2021)

The glomerular filtration rate (GFR), according to which the drug dose for patients with chronic kidney disease (CKD) is adjusted, is computed with estimators (eGFR) that are developed specifically for CKD. These particular types of estimators are al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ca54d5a7f67161490b0fbe70d9e904
http://europepmc.org/articles/PMC7915939

Impact of the World Health Organization Pain Treatment Guidelines and the European Medicines Agency Safety Recommendations on nonsteroidal anti-inflammatory drug use in Lithuania: An observational study

Autor: Skaistė Kasciuškevičiūtė, Aušra Vendzelytė, Edmundas Kaduševičius, Kęstutis Petrikonis, Gintautas Gumbrevičius, Arūnas Ščiupokas

Publikováno v: Medicina, Basel : MDPI, 2018, vol. 54, no. 2, 30, p. 1-13
Medicina
Medicina; Volume 54; Issue 2; Pages: 30

Background and objective: Irrational use of nonsteroidal anti-inflammatory drugs (NSAIDs) is the main cause of adverse effects-associated hospitalizations among all medication groups leading to extremely increased costs for health care. Pharmacoepide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3618ace4105cd1a1db0141baedb39e
https://library.lsmuni.lt/LSMU:ELABAPDB28659315&prefLang=en_US

Comparison of the pharmacokinetic and pharmacodynamic properties of two recombinant granulocyte colony-stimulating factor formulations after single subcutaneous administration to healthy volunteers

Autor: Rima Kregždytė, Audrius Sveikata, Vidmantas Fokas, Vytautas Janulionis, Gintautas Gumbrevičius, Kastytis Šeštakauskas

Publikováno v: Medicina, Wrocław : Elsevier, 2014, vol. 50, no. 3, p. 144-149
Medicina, Vol 50, Iss 3, Pp 144-149 (2014)
Medicina
Volume 50
Issue 3
Pages 144-149
Medicina; Volume 50; Issue 3; Pages: 144-149

Background and objective: The aim of this randomized, single dose, two-period crossover study with two weeks wash-out period was the demonstration of bioequivalence of two recombinant human granulocyte colony-stimulating factor (rG-CSF) formulations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcda6d0ac603589a3801e6180dbf8631
https://library.lsmuni.lt/LSMU:ELABAPDB5694454&prefLang=en_US

Efficacy, tolerability, and preference of mirtazapine orally disintegrating tablets in depressed patients: a 17-week naturalistic study in Lithuania

Autor: Sveikatiene R, Audrius Sveikata, Gintautas Gumbrevičius, Adomaitiene, Fokas, Danileviciūte

Publikováno v: Medicina; Volume 45; Issue 10; Pages: 778
Medicina
Volume 45
Issue 10

Mirtazapine is an established antidepressant with well-documented efficacy demonstrated in controlled clinical trials. However, the gap between the results obtained in controlled clinical trials and everyday clinical practice exists. Therefore, the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf99c3c40a187408fe4f47faa6c10b1
https://doi.org/10.3390/medicina45100101