Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gintarė Sendžikaitė"'
Autor:
Douglas J. MacKenzie, Neil A. Robertson, Iqbal Rather, Claire Reid, Gintare Sendzikaite, Hazel Cruickshanks, Tony McBryan, Andrew Hodges, Catrin Pritchard, Karen Blyth, Peter D. Adams
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Approximately 10% of human colorectal cancer (CRC) are associated with activated BRAFV600E mutation, typically in absence of APC mutation and often associated with a CpG island methylator (CIMP) phenotype. To protect from cancer, normal inte
Externí odkaz:
https://doaj.org/article/bcd05a25f9ea4e0fb735b64780294901
Autor:
Gintarė Sendžikaitė, Courtney W. Hanna, Kathleen R. Stewart-Morgan, Elena Ivanova, Gavin Kelsey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
PWWP domains of DNMT3A and DNMT3B are proposed to interact with H3K36me3. Here the authors present a mouse model carrying a D329A point mutation in the DNMT3A PWWP domain and find this causes dominant postnatal growth retardation, with aberrant progr
Externí odkaz:
https://doaj.org/article/bf208415af2e4e6986d414cb8d984ae3
Autor:
Gavin Kelsey, Gintarė Sendžikaitė
Publikováno v:
Essays in Biochemistry
Epigenetic information in the mammalian oocyte has the potential to be transmitted to the next generation and influence gene expression; this occurs naturally in the case of imprinted genes. Therefore, it is important to understand how epigenetic inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75801e87cf078a609b2d26b235aa8af8
https://doi.org/10.1042/ebc20190043
https://doi.org/10.1042/ebc20190043
Autor:
Kathleen R. Stewart-Morgan, Gintarė Sendžikaitė, Elena Ivanova, Gavin Kelsey, Courtney W. Hanna
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
DNA methyltransferases (DNMTs) deposit DNA methylation, which regulates gene expression and is essential for mammalian development. Histone post-translational modifications modulate the recruitment and activity of DNMTs. The PWWP domains of DNMT3A an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1941e71753449ce94d836c5514caa4a4
http://link.springer.com/article/10.1038/s41467-019-09713-w
http://link.springer.com/article/10.1038/s41467-019-09713-w