Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Gino R, Somers"'
Autor:
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D. Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M. Abegglen, Daniel Albertson, Jonathan L. Finlay, Jordan R. Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B. Alexandrov, Gino R. Somers, Joshua D. Schiffman, Varda Rotter, David Malkin, Adam Shlien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Li-Fraumeni syndrome (LFS) is associated with pathogenic germline TP53 variants and predisposes patients to cancer; understanding the evolution and drivers of LFS-related tumours remains crucial. Here, the authors analyse 22 LFS tumours using whole-g
Externí odkaz:
https://doaj.org/article/6313943fa94246f49c0f01dd1873ed40
Publikováno v:
Otolaryngology Case Reports, Vol 21, Iss , Pp 100383- (2021)
Glial heterotopia are rare, benign tumors most commonly found around the nasal cavity, but extra-nasal heterotopias have also been observed. We present an anatomically rare case of glial heterotopia overlying the left occipital condyle. Excisional bi
Externí odkaz:
https://doaj.org/article/7868246598484ed280f38dd146839046
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations
Autor:
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W. Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D. Anderson, Arun K. Ramani, Kyoko E. Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D. Wasserman, Rosemarie E. Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A. Whitlock, Stephen W. Scherer, Kathy Chun, Martin J. Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramaswamy, Gino R. Somers, Lianna Kyriakopoulou, Johann Hitzler, Mary Shago, Daniel A. Morgenstern, Uri Tabori, Stephen Meyn, Meredith S. Irwin, David Malkin, Adam Shlien
Publikováno v:
Nature Cancer. 4:203-221
We conducted integrative somatic–germline analyses by deeply sequencing 864 cancer-associated genes, complete genomes and transcriptomes for 300 mostly previously treated children and adolescents/young adults with cancer of poor prognosis or with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc564393b318b298215f3cddc8037c8
https://doi.org/10.1038/s43018-022-00474-y
https://doi.org/10.1038/s43018-022-00474-y
Autor:
Nina Lenherr‐Taube, Carol KL Lam, Reza Vali, Amer Shammas, Paolo Campisi, Faisal Zawawi, Gino R Somers, Jennifer Stimec, Ozgur Mete, Andy KO Wong, Etienne Sochett
Publikováno v:
JBMR Plus, Vol 4, Iss 3, Pp n/a-n/a (2020)
ABSTRACT Primary hyperparathyroidism is a condition that occurs infrequently in children. Parathyroid carcinoma, as the underlying cause of hyperparathyroidism in this age group, is extraordinarily rare, with only a few cases reported in the literatu
Externí odkaz:
https://doaj.org/article/1ccbdf1938ee4ac9bf746e1dd6d39413
Autor:
Neal Sondheimer, Stacy Hewson, Jessie M. Cameron, Gino R. Somers, Jane Dunning Broadbent, Marcello Ziosi, Catarina Maria Quinzii, Ali B. Naini
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 12, Iss C, Pp 23-27 (2017)
Coenzyme Q10 (CoQ10) or ubiquinone is one of the two electron carriers in the mitochondrial respiratory chain which has an essential role in the process of oxidative phosphorylation. Defects in CoQ10 synthesis are usually associated with the impaired
Externí odkaz:
https://doaj.org/article/753e2cc8a6654c369b7d2bc8b9a8c4b8
Autor:
Lisa Hung, Alper Celik, Xiaojun Yin, Kai Yu, Alireza Berenjy, Akash Kothari, Helena Obernolte, Julia E. M. Upton, Katrine Lindholm Bøgh, Gino R. Somers, Iram Siddiqui, Martin Grealish, Fayez A. Quereshy, Katherina Sewald, Priscilla P. L. Chiu, Thomas Eiwegger
Publikováno v:
Hung, L, Celik, A, Yin, X, Yu, K, Berenjy, A, Kothari, A, Obernolte, H, Upton, J E M, Lindholm Bøgh, K, Somers, G R, Siddiqui, I, Grealish, M, Quereshy, F A, Sewald, K, Chiu, P P L & Eiwegger, T 2023, ' Precision cut intestinal slices, a novel model of acute food allergic reactions ', Allergy, vol. 78, no. 2, pp. 500-511 . https://doi.org/10.1111/all.15579
Background: Food allergy affects up to 8% of the pediatric population. Despite ongoing efforts, treatment options remain limited. Novel models of food allergy are needed to study response patterns downstream of IgE-crosslinking and evaluate drugs mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f039022cf3c19f43574387d5f4d34871
https://pubmed.ncbi.nlm.nih.gov/36377289
https://pubmed.ncbi.nlm.nih.gov/36377289
Autor:
James R, Wright, Suzanne, Chan, Eric K, Morgen, Raymond T A, Maung, Marie-Anne, Brundler, Dina, El Demellawy, Robert B, Fraser, Kyle C, Kurek, Fergall, Magee, Elizabeth, Nizalik, Luc L, Oligny, Gino R, Somers, Camelia, Stefanovici, Jefferson, Terry
Publikováno v:
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 25(6)
Workload measurement is important to help determine optimal staffing and workload distribution for pathology laboratories. The Level 4 Equivalent (L4E) System is the most widely used Anatomical Pathology (AP) workload measurement tool in Canada. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e9f6a03cbc3e4597a1fdfcf99a24049
https://pubmed.ncbi.nlm.nih.gov/36082400
https://pubmed.ncbi.nlm.nih.gov/36082400
Autor:
Gino R. Somers, Anita Nagy
Publikováno v:
Surgical Pathology Clinics. 13:763-782
Undifferentiated sarcomas of soft tissue and bone have been defined as tumors with no identifiable morphologic, immunohistochemical, or molecular features indicating tumor cell origin. In young patients, these tumors frequently have a round or spindl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9d8bfc55b3685e8e815bec60f8b3ef7
https://doi.org/10.1016/j.path.2020.08.004
https://doi.org/10.1016/j.path.2020.08.004
Autor:
Kelley Zwicker, Gino R. Somers, Leonardo R. Brandão, Philip John, Soumitra Tole, Josée Dubois, Julie Powell, Elena Pope, Michèle David, Claudia Malic, Victoria Kendrick, Victoria E. Price
Publikováno v:
Thrombosis Research. 196:626-634
Long before the classification of vascular anomalies from the International Society for the Study of Vascular Anomalies (ISSVA) provided a framework to differentiate vascular anomalies, otherwise known as vascular birthmarks, it was recognized that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8c5e25aaa4d64a94e4a8ae472bcae3
https://doi.org/10.1016/j.thromres.2019.06.004
https://doi.org/10.1016/j.thromres.2019.06.004
Publikováno v:
Pediatric dermatologyREFERENCES. 38(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a021d5b826e13921788ebaa6cf56464
https://pubmed.ncbi.nlm.nih.gov/34750883
https://pubmed.ncbi.nlm.nih.gov/34750883