Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gino Bradica"'
Autor:
Conan S. Young, Gino Bradica, Charlie E. Hart, Anuradha Karunanidhi, Reva M. Street, Lyndsey Schutte, Jeffrey O. Hollinger
Publikováno v:
Journal of Tissue Engineering, Vol 1, Iss 1 (2010)
Human platelet-derived growth factor-BB (hPDGF-BB) is a basic polypeptide growth factor released from platelets at the injury site. It is a multifunctional molecule that regulates DNA synthesis and cell division and induces biological effects that
Externí odkaz:
https://doaj.org/article/30daa1f1ac7f417f9c2f13a428efdc66
Autor:
Joseph P. Gaut, Joseph P. Vacanti, David M. Hoganson, Mark A. Randolph, Rachel L. Goldstein, Scott M. Goldman, Gino Bradica, Amanda M Westman
Publikováno v:
Journal of Biomaterials Applications. 33:1070-1079
Extracellular matrix materials mechanically dissociated into submillimeter particles have a larger surface area than sheet materials and enhanced cellular attachment. Decellularized porcine mesothelial extracellular matrix microparticles were seeded
Autor:
Matthew F. Koff, Emme Castiglione, Taralyn M. McCarrel, Lisa A. Fortier, Ryan A. Saska, Susannah L. Gilbert, Gino Bradica, Sarah L. Pownder
Publikováno v:
CARTILAGE. 8:406-416
ObjectiveTo evaluate a biphasic cartilage repair device (CRD) for feasibility of arthroscopic implantation, safety, biocompatibility, and efficacy for long-term repair of large osteochondral defects.MethodsThe CRD was press-fit into defects (10 mm di
Autor:
Xiang-Hong Liu, Scott M. Goldman, Joseph P. Vacanti, Kathleen Hiltz, Amanda M. Meppelink, Gino Bradica, Kathryn Barron, Xing-Hua Wang, Armand Keating, David M. Hoganson
Publikováno v:
Cytotherapy. 18:729-739
Background aims The use of bone marrow–derived mesenchymal stromal cells (MSCs) in cell-based therapies is currently being developed for a number of diseases. Thus far, the clinical results have been inconclusive and variable, in part because of th
Publikováno v:
Ultrasound in Medicine & Biology. 41:1842-1852
This study was performed to investigate osteoblastogenesis of human mesenchymal stem cells (hMSCs) cultured in 3-D scaffolds stimulated with low-intensity pulsed ultrasound and to identify the underlying mechanism mediated by soluble receptor activat
Autor:
Patrick W. Satchell, Lisa A. Fortier, Lauren V. Schnabel, Rebecca M. Williams, Hussni O. Mohammed, Emme Castiglione, Sarah L. Pownder, Ryan A. Saska, Gino Bradica, Hollis G. Potter, Keir A. Ross
Publikováno v:
Cartilage
Objective: The aim of this study was to determine if the noninvasive or minimally invasive and nondestructive imaging techniques of quantitative T2-mapping or multiphoton microscopy (MPM) respectively, could detect differences in cartilage collagen o
Autor:
Edward M. Schwarz, Laura Yanoso-Scholl, Michael J. Zuscik, Regis J. O'Keefe, Justin A. Jacobson, Gino Bradica, Amy L. Lerner, Hani A. Awad
Publikováno v:
Journal of Biomedical Materials Research Part A. :717-726
Advances in biomaterial fabrication have introduced numerous innovations in designing scaffolds for bone tissue engineering. Often, the focus has been on fabricating scaffolds with high and interconnected porosity that would allow for cellular seedin
Autor:
Gino Bradica, J. Russell Parsons, Charles E. Hart, Eric Breitbart, J. Patrick O'Connor, Sheldon S. Lin, Loay Al-Zube
Publikováno v:
Journal of Orthopaedic Research. 27:1074-1081
Diabetes mellitus is a common systemic disease that has been associated with poor fracture healing outcomes. The mechanism through which diabetes impairs bone regeneration is unknown. One possible mechanism may be related to either decreased or uncoo
Autor:
Cynthia Gooch, David L. Butler, Matthew R. Dressler, Natalia Juncosa-Melvin, Victor S. Nirmalanandhan, Marepalli B. Rao, Gino Bradica, Jason T. Shearn
Publikováno v:
Journal of Biomechanical Engineering. 129:919-923
Our group has shown that numerous factors can influence how tissue engineered tendon constructs respond to in vitro mechanical stimulation. Although one study showed that stimulating mesenchymal stem cell (MSC)–collagen sponge constructs significan
Autor:
Natalia Juncosa-Melvin, Victor S. Nirmalanandhan, David L. Butler, Gino Bradica, John R. West, Marc T. Galloway, Cynthia Gooch, Jason T. Shearn, Gregory P. Boivin
Publikováno v:
Tissue Engineering. 12:2291-2300
The objective of this study was to determine how mechanical stimulation affects the biomechanics and histology of stem cell-collagen sponge constructs used to repair central rabbit patellar tendon defects. Autogenous tissue-engineered constructs were