Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Ginny L, Bumgardner"'
Autor:
Jason M. Zimmerer, Jing L. Han, Chelsea M. Peterson, Qiang Zeng, Bryce A. Ringwald, Clarissa Cassol, Sachi Chaudhari, Madison Hart, Jessica Hemminger, Anjali Satoskar, Mahmoud Abdel-Rasoul, Jiao-Jing Wang, Robert T. Warren, Zheng J. Zhang, Christopher K. Breuer, Ginny L. Bumgardner
Publikováno v:
Am J Transplant
CCR5 KO kidney transplant (KTx) recipients are extraordinarily high alloantibody producers and develop pathology that mimics human antibody-mediated rejection (AMR). C57BL/6 and CCR5 KO mice (H-2(b)) were transplanted with A/J kidneys (H-2(a)); selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ccc1ef7cde2c389259d59da8fac2a9
https://doi.org/10.1111/ajt.16988
https://doi.org/10.1111/ajt.16988
Autor:
Jing Han, Madison M Hart, Ginny L. Bumgardner, Robert T. Warren, Chelsea M Peterson, Bryce A Ringwald, Sachi R Chaudhari, Mahmoud Abdel-Rasoul, Jason M. Zimmerer
Publikováno v:
J Immunol
Hepatocyte transplant represents a treatment for metabolic disorders but is limited by immunogenicity. Our prior work identified the critical role of CD8+ T cells, with or without CD4+ T cell help, in mediating hepatocyte rejection. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bd6691be0e085cab8786d555bd82bd
https://doi.org/10.4049/jimmunol.2100334
https://doi.org/10.4049/jimmunol.2100334
Autor:
Kenneth Washburn, Austin Schenk, April Logan, Ashraf El-Hinnawi, Navdeep Singh, Amer Rajab, Ginny L. Bumgardner, Guy Brock
Publikováno v:
Am J Surg
Background Hypothermic machine perfusion (HMP) parameters are influenced by donor variables which further affect recipient outcome. Interplay between these parameters can help to predict kidney performance on pump and the long term outcome. Methods A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bbcb1d2e24d07fec2ef995dcdaed10
https://europepmc.org/articles/PMC9017432/
https://europepmc.org/articles/PMC9017432/
Publikováno v:
J Immunol
CD8+ T cells have conventionally been studied in relationship to pathogen or tumor clearance. Recent reports have identified novel functions of CXCR5+CD8+ T cells that can home to lymphoid follicles, a key site of Ab production. In this review, we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb056a1d9b037c0ded74bc7f7cdd53b
https://europepmc.org/articles/PMC8486376/
https://europepmc.org/articles/PMC8486376/
Publikováno v:
The Journal of Immunology. 208:53.06-53.06
Antibody-mediated rejection is a significant contributor to transplant rejection. Our prior work identified a novel subset of CXCR5+CD8+ T cells (CD8+ TAb-supp cells) that suppresses alloantibody production by mediating cytotoxic killing of IgG+ allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc38a9e8b500880aa236e026e2882b27
https://doi.org/10.4049/jimmunol.208.supp.53.06
https://doi.org/10.4049/jimmunol.208.supp.53.06
Autor:
Jing Light Han, Jason Zimmerer, Qiang Zeng, Sachi Chaudhari, Christopher Breuer, Ginny L Bumgardner
Publikováno v:
The Journal of Immunology. 208:175.09-175.09
Kidney transplant (KTx) into CCR5 KO mice is an excellent model to study AMR immunobiology due to a heightened humoral response posited to be secondary to impaired CD4+Treg cell trafficking to the allograft. We have observed that adoptive cell therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152e768af863c9d0452ea67e5e52a621
https://doi.org/10.4049/jimmunol.208.supp.175.09
https://doi.org/10.4049/jimmunol.208.supp.175.09
Autor:
Jing Light Han, Jason Zimmerer, Qiang Zeng, Sachi Chaudhari, Christopher Breuer, Ginny L Bumgardner
Publikováno v:
The Journal of Immunology. 208:175.16-175.16
CXCR5+CD8+TAb-supp cells inhibit alloantibody (alloAb) production, AMR, and prolong graft survival in mouse models. To determine if this cell therapy is compatible with standard immunosuppression (IS) strategies, we investigate the interaction of CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6cf921983c84ef56e3333f4d75b667
https://doi.org/10.4049/jimmunol.208.supp.175.16
https://doi.org/10.4049/jimmunol.208.supp.175.16
Autor:
Jason M. Zimmerer, Phillip H. Horne, Lori A. Fiessinger, Mason G. Fisher, Kartika Jayashankar, Sierra F. Garcia, Mahmoud Abdel-Rasoul, Nico Van Rooijen, Ginny L. Bumgardner M.D., Ph.D., F.A.C.S.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Allospecific T memory cell responses in transplant recipients arise from environmental exposure to previous transplantation or cross-reactive heterologous immunity. Unfortunately, these memory responses pose a significant barrier to the survival of t
Externí odkaz:
https://doaj.org/article/63c26d8282bd4c38afaa132f999d1348
Autor:
April Logan, Austin Schenk, Ashraf El-Hinnawi, Navdeep Singh, Kenneth Washburn, Amer Rajab, Ginny L. Bumgardner
Publikováno v:
Clinical Transplantation. 34
The use of diabetic kidneys is increasing worldwide with better outcome than being on waitlist and possible reversal of diabetic changes in transplanted kidneys. But particular caution is warranted in diabetic donor-recipient combination. Total 1223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e66953905f85b346151644b227dc79b
https://doi.org/10.1111/ctr.14115
https://doi.org/10.1111/ctr.14115
Autor:
Ashraf El-Hinnawi, Jason A. Benedict, Guy Brock, Mitchell L. Henry, Elmahdi A. Elkhammas, Ronald P. Pelletier, Amer Rajab, Ginny L. Bumgardner, Iyore James, Michelle C. Nguyen, Christina Avila
Publikováno v:
Clin Transplant
BACKGROUND: Hospital readmission (HR) after surgery is considered a quality metric. METHODS: Data on 2371 first-time adult kidney transplant (KT) recipients were collected to analyze the “early” (≤30 days) and “late” (31–365 days) HR patt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9353a46291d83b7260d114d7fae6e41a
https://doi.org/10.1111/ctr.13822
https://doi.org/10.1111/ctr.13822