Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ginny I Chen"'
Autor:
Anthony B. Mak, Allison M.L. Nixon, Saranya Kittanakom, Jocelyn M. Stewart, Ginny I. Chen, Jasna Curak, Anne-Claude Gingras, Ralph Mazitschek, Benjamin G. Neel, Igor Stagljar, Jason Moffat
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 951-963 (2012)
The pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types. Despite its utility as a cancer progenitor cell marker, CD133 protein regulation and molecular
Externí odkaz:
https://doaj.org/article/7c367e4d72024b2cb906fd603be9e02d
Autor:
Marc R. Fabian, Simon W. M. Eng, Jean-François Côté, Wade H. Dunham, Halil Bagci, Mikhail Bashkurov, Quaid Morris, Graham MacLeod, Ginny I. Chen, James D.R. Knight, Ji-Young Youn, Bhavisha Rathod, Stephane Angers, Anne-Claude Gingras, Seo Jung Hong
Publikováno v:
Molecular cell. 69(3)
mRNA processing, transport, translation, and ultimately degradation involve a series of dedicated protein complexes that often assemble into large membraneless structures such as stress granules (SGs) and processing bodies (PBs). Here, systematic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc38c605863d322fc165ba1e643a93dc
https://pubmed.ncbi.nlm.nih.gov/29395058
https://pubmed.ncbi.nlm.nih.gov/29395058
Autor:
Jernej Ule, Benjamin J. Blencowe, Anne-Claude Gingras, Zhen-Yuan Lin, Laura E. Easton, Bushra Raj, Manuel Irimia, Timothy Sterne-Weiler, Ginny I. Chen, Dave O'Hanlon, Ulrich Braunschweig, Eduardo Eyras
Publikováno v:
Molecular Cell. 56:90-103
The vertebrate and neural-specific Ser/Arg (SR)-related protein nSR100/SRRM4 regulates an extensive program of alternative splicing with critical roles in nervous system development. However, the mechanism by which nSR100 controls its target exons is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d810fd8ef1503b31e3583bcaa2c3da
https://doi.org/10.1016/j.molcel.2014.08.011
https://doi.org/10.1016/j.molcel.2014.08.011
Autor:
Daniel Coomber-Alford, Benjamin Caldwell, Daniel Morley, Maurizio La Mura, Alpesh Patel, Ginny I Chen, Risha E Thomas, Chung-Pei Ou, Hua Bai, David M Garner, Pantelis Georgiou, Christofer Toumazou, Ines M Q Brizido, Linglan Zhang, Krishna Amin-Desai, Chan-Ju A Wang, Sara Temelso, Samuel Reed, Leila Shepherd, Panteleimon Athanasiou, John C Joyce, Karen S Jordan, Sreekala Sathyavruthan
Publikováno v:
Nature Methods. 10:641-646
We developed an integrated chip for real-time amplification and detection of nucleic acid using pH-sensing complementary metal-oxide semiconductor (CMOS) technology. Here we show an amplification-coupled detection method for directly measuring releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfe4eb1753a48ddafb477948d549e99
https://doi.org/10.1038/nmeth.2520
https://doi.org/10.1038/nmeth.2520
Autor:
Anne-Claude Gingras, Allison M.L. Nixon, Ginny I. Chen, Saranya Kittanakom, Jasna Curak, Jason Moffat, Benjamin G. Neel, Igor Stagljar, Ralph Mazitschek, Anthony B. Mak, Jocelyn M. Stewart
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 951-963 (2012)
SummaryThe pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types. Despite its utility as a cancer progenitor cell marker, CD133 protein regulation and mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01b9561ec0f3dcdaa358043e842c535
https://doi.org/10.1016/j.celrep.2012.09.016
https://doi.org/10.1016/j.celrep.2012.09.016
Autor:
Anne-Claude Gingras, Jonathan B. Olsen, Sergei V. Chetyrkin, Guoqing Zhong, Denitza Roudeva, Anthony B. Mak, Ruth Isserlin, Jason Moffat, Cuihong Wan, Edyta Marcon, Sandra Smiley, Ginny I. Chen, Andrew Emili, Kim Blakely, Jack Greenblatt, Zuyao Ni, Joyce Li, Thanuja Punna, Johannes A. Hewel, Konstantina Karamboulas
Publikováno v:
Molecular & Cellular Proteomics. 9:811-823
Protein complexes and protein-protein interactions are essential for almost all cellular processes. Here, we establish a mammalian affinity purification and lentiviral expression (MAPLE) system for characterizing the subunit compositions of protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2ece3f1d3832476628d70fade10237
https://doi.org/10.1074/mcp.m000002-mcp201
https://doi.org/10.1074/mcp.m000002-mcp201
Autor:
Ginny I. Chen, Alexey I. Nesvizhskii, Sidharth Chaudhry, Marilyn Goudreault, Lisa M. D'Ambrosio, Brett Larsen, Anne-Claude Gingras, Frank Sicheri, Amy Sanchez, Michelle J. Kean, Ruedi Aebersold, Brian Raught, Michael Mullin
Publikováno v:
Molecular & Cellular Proteomics. 8:157-171
The serine/threonine protein phosphatases are targeted to specific subcellular locations and substrates in part via interactions with a wide variety of regulatory proteins. Understanding these interactions is thus critical to understanding phosphatas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5c3dc5904a99687d07e17868f8cc70
https://doi.org/10.1074/mcp.m800266-mcp200
https://doi.org/10.1074/mcp.m800266-mcp200
Autor:
Ginny I. Chen, Anne-Claude Gingras
Publikováno v:
Methods. 42:298-305
Association of serine/threonine phosphatases with regulatory proteins is a key component of their specificity, and the identification of these binding partners is critical to understanding phosphatases function and regulation. Affinity-purification/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a639251c6827c7735299c5e57cb54da2
https://doi.org/10.1016/j.ymeth.2007.02.018
https://doi.org/10.1016/j.ymeth.2007.02.018
Autor:
Alexei Poliakov, Brett Larsen, David G. Wilkinson, Ginny I. Chen, Claus Jørgensen, Tony Pawson, Andrew Sherman, Rune Linding, Adrian Pasculescu, Marilyn Hsiung
Publikováno v:
Science (New York, N.Y.). 326(5959)
Cells have self-organizing properties that control their behavior in complex tissues. Contact between cells expressing either B-type Eph receptors or their transmembrane ephrin ligands initiates bidirectional signals that regulate cell positioning. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593faa3e03add253bd9a0e78c7d30226
https://pubmed.ncbi.nlm.nih.gov/20007894
https://pubmed.ncbi.nlm.nih.gov/20007894
Publikováno v:
EMBO Reports
Phosphorylation of histone H2AX on Ser 139 (gammaH2AX) is one of the earliest events in the response to DNA double-strand breaks; however, the subsequent removal of gammaH2AX from chromatin is less understood, despite being a process tightly coordina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0321415855efa147cfd787113fdd516
https://europepmc.org/articles/PMC2608198/
https://europepmc.org/articles/PMC2608198/
