Vasopressin-oxytocin-type signaling is ancient and has a conserved water homeostasis role in euryhaline marine planarians.

Autor: Kobayashi A; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Hamada M; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Yoshida MA; Oki Marine Biological Station, Shimane University, 194 Kamo, Okinoshima, Oki, Shimane 685-0024, Japan., Kobayashi Y; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan.; Laboratory for Aquatic Biology, Department of Fisheries, Faculty of Agriculture, Kindai University, Nakamachi, Nara, Japan., Tsutsui N; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan.; Department of Marine Bioresources, Faculty of Bioresources, Mie University, Tsu, Mie 514-8507, Japan., Sekiguchi T; Noto Marine Laboratory, Institute of Nature and Environmental Technology, Division of Marine Environmental Studies, Kanazawa University, Ogi, Noto-cho, Ishikawa 927-0553, Japan.; School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand., Matsukawa Y; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Maejima S; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Gingell JJ; Vertex Pharmaceuticals (Europe) Ltd., Milton Park, Abingdon OX11 4RW, UK., Sekiguchi S; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Hamamoto A; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan.; Department of Biology, Faculty of Science, Okayama University, 3-1-1 Kita-ku, Tsushimanaka, Okayama 700-8530, Japan., Hay DL; School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; Department of Pharmacology and Toxicology, University of Otago, Otago, New Zealand., Morris JF; Department of Physiology, Anatomy, and Genetic, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford OX1 3QX, UK., Sakamoto T; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan., Sakamoto H; Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan.; Department of Physiology, Anatomy, and Genetic, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

Publikováno v: Science advances [Sci Adv] 2022 Mar 04; Vol. 8 (9), pp. eabk0331. Date of Electronic Publication: 2022 Mar 04.

Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors.

Autor: Garelja ML; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand., Au M; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand., Brimble MA; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand., Gingell JJ; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand., Hendrikse ER; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand., Lovell A; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand., Prodan N; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand., Sexton PM; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Siow A; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand., Walker CS; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand., Watkins HA; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand., Williams GM; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand., Wootten D; Drug Discovery Biology and Department of Pharmacology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Yang SH; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand., Harris PWR; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, 1010, New Zealand., Hay DL; School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, 1010, New Zealand.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Feb 26; Vol. 3 (2), pp. 246-262. Date of Electronic Publication: 2020 Feb 26 (Print Publication: 2020).

Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex.

Autor: Simms J; Aston University , Birmingham B4 7ET , U.K.; Coventry University , Priory Street , Coventry CV1 5FB , U.K., Uddin R; Aston University , Birmingham B4 7ET , U.K., Sakmar TP; The Rockefeller University , 1230 York Avenue , New York , New York 10065 , United States., Gingell JJ; University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand., Garelja ML; University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand., Hay DL; University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand., Brimble MA; University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand., Harris PW; University of Auckland , 3A Symonds Street , Auckland 1010 , New Zealand., Reynolds CA; University of Essex , Wivenhoe Park , Colchester CO4 3SQ , U.K., Poyner DR; Aston University , Birmingham B4 7ET , U.K.

Publikováno v: Biochemistry [Biochemistry] 2018 Aug 14; Vol. 57 (32), pp. 4915-4922. Date of Electronic Publication: 2018 Jul 25.

N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.

Autor: Lee SM; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center , 975 NE 10th Street BRC 462B, Oklahoma City, Oklahoma 73104, United States., Booe JM; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center , 975 NE 10th Street BRC 462B, Oklahoma City, Oklahoma 73104, United States., Gingell JJ, Sjoelund V; Proteomics Division of the Laboratory for Molecular Biology and Cytometry Research, University of Oklahoma Health Sciences Center , 975 NE 10th Street, Oklahoma City, Oklahoma 73104, United States., Hay DL, Pioszak AA; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center , 975 NE 10th Street BRC 462B, Oklahoma City, Oklahoma 73104, United States.

Publikováno v: Biochemistry [Biochemistry] 2017 Jul 05; Vol. 56 (26), pp. 3380-3393. Date of Electronic Publication: 2017 Jun 26.

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.

Autor: Watkins HA; From the School of Biological Sciences, the Maurice Wilkins Centre for Molecular Biodiscovery, and., Chakravarthy M; From the School of Biological Sciences., Abhayawardana RS; From the School of Biological Sciences., Gingell JJ; From the School of Biological Sciences, the Maurice Wilkins Centre for Molecular Biodiscovery, and., Garelja M; From the School of Biological Sciences., Pardamwar M; the School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom., McElhinney JM; the School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom., Lathbridge A; the School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom., Constantine A; the School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom., Harris PW; the Maurice Wilkins Centre for Molecular Biodiscovery, and the School of Chemical Sciences, University of Auckland, Auckland 1010, New Zealand., Yuen TY; the Maurice Wilkins Centre for Molecular Biodiscovery, and the School of Chemical Sciences, University of Auckland, Auckland 1010, New Zealand., Brimble MA; the Maurice Wilkins Centre for Molecular Biodiscovery, and the School of Chemical Sciences, University of Auckland, Auckland 1010, New Zealand., Barwell J; the School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, United Kingdom., Poyner DR; the School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, United Kingdom., Woolley MJ; the School of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Conner AC; the School of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Pioszak AA; the Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104., Reynolds CA; the School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom, reync@essex.ac.uk., Hay DL; From the School of Biological Sciences, the Maurice Wilkins Centre for Molecular Biodiscovery, and dl.hay@auckland.ac.nz.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2016 May 27; Vol. 291 (22), pp. 11657-75. Date of Electronic Publication: 2016 Mar 24.