Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ginevra Giglioli"'
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giuseppe Maccari, Giada Antonelli, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Giulia Piccini, Concetta De Santi, Claudia Sala, Duccio Medini, Emanuele Montomoli, Piet Maes, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Omicron strains of SARS-CoV-2 have displayed high transmissibility and immunological escape to antibody responses derived from natural infection and vaccination. Here the authors compare the antibody response to vaccination and natural infection, ass
Externí odkaz:
https://doaj.org/article/4dbdad3909b344fe846162d4999f1efb
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Valentina Abbiento, Giada Antonelli, Piero Pileri, Noemi Manganaro, Elisa Pantano, Giuseppe Maccari, Silvia Marchese, Lorena Donnici, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Concetta De Santi, Massimiliano Fabbiani, Ilaria Rancan, Mario Tumbarello, Francesca Montagnani, Claudia Sala, Duccio Medini, Raffaele De Francesco, Emanuele Montomoli, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
SARS-CoV-2 vaccines and infection induce antibody responses but the evolution of subsequent variants has resulted in the development of escape mutants. Here the authors characterise, at single cell level, the antibody response in donors after a third
Externí odkaz:
https://doaj.org/article/8bf9f127c9594148a4055cebaa03c05d
Autor:
Emanuele Andreano, Ida Paciello, Silvia Marchese, Lorena Donnici, Giulio Pierleoni, Giulia Piccini, Noemi Manganaro, Elisa Pantano, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Piet Maes, Concetta De Santi, Claudia Sala, Emanuele Montomoli, Raffaele De Francesco, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Externí odkaz:
https://doaj.org/article/f6ef68614439432b9c2c0fa9a78d436d
mRNA vaccines and hybrid immunity use different B cell germlines to neutralize Omicron BA.4 and BA.5
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giuseppe Maccari, Giada Antonelli, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Giulia Piccini, Concetta De Santi, Claudia Sala, Duccio Medini, Emanuele Montomoli, Piet Maes, Rino Rappuoli
SARS-CoV-2 omicron BA.4 and BA.5, characterized by high transmissibility and ability to escape natural and vaccine induced immunity, are rampaging worldwide. To understand the escape mechanisms, we tested the neutralizing activity against omicron BA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e5f6ef68967356f4221399df4ab9cc7
https://doi.org/10.1101/2022.08.04.502828
https://doi.org/10.1101/2022.08.04.502828
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Valentina Abbiento, Giada Antonelli, Piero Pileri, Noemi Manganaro, Elisa Pantano, Giuseppe Maccari, Silvia Marchese, Lorena Donnici, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Concetta De Santi, Massimiliano Fabbiani, Ilaria Rancan, Mario Tumbarello, Francesca Montagnani, Claudia Sala, Duccio Medini, Raffaele De Francesco, Emanuele Montomoli, Rino Rappuoli
The continuous evolution of SARS-CoV-2 generated highly mutated variants, like omicron BA.1 and BA.2, able to escape natural and vaccine-induced primary immunity1,2. The administration of a third dose of mRNA vaccines induces a secondary response wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db7c3398e08840fdaaadbf224ca0250f
https://doi.org/10.1101/2022.05.09.491201
https://doi.org/10.1101/2022.05.09.491201
Autor:
Rino Rappuoli, Emanuele Andreano, Ida Paciello, Silvia Marchese, Lorena Donnici, Giulio Pierleoni, Giulia Piccini, Noemi Manganaro, Elisa Pantano, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Piet Maes, Concetta De Santi, Claudia Sala, Emanuele Montomoli, Raffaele De Francesco
SARS-CoV-2 vaccines, administered to billions of people worldwide, are mitigating the effects of the COVID-19 pandemic, however little is known about the molecular basis of antibody cross-protection to emerging variants, such as Omicron (B.1.1.529),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e314497d0a0b1bcfe21f04e6b91d5a91
https://doi.org/10.21203/rs.3.rs-1330153/v1
https://doi.org/10.21203/rs.3.rs-1330153/v1
Autor:
Concetta De Santi, Linda Benincasa, Inesa Hyseni, Ida Paciello, Massimiliano Fabbiani, Ginevra Giglioli, Giulia Piccini, Claudia Sala, Rino Rappuoli, Ilaria Rancan, Piero Pileri, Elisa Pantano, Valentina Abbiento, Emanuele Montomoli, Noemi Manganaro, Margherita Leonardi, Emanuele Andreano, Francesca Montagnani, Mario Tumbarello
To understand the nature of the antibody response to SARS-CoV-2 vaccination, we analyzed at single cell level the B cell responses of five naïve and five convalescent people immunized with the BNT162b2 mRNA vaccine. Convalescents had higher frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f17019846664e992e71407be411e30
https://doi.org/10.1101/2021.08.12.456077
https://doi.org/10.1101/2021.08.12.456077
Autor:
Claudia Sala, Concetta De Santi, Rino Rappuoli, Noemi Manganaro, Ida Paciello, Piero Pileri, Mario Tumbarello, Elisa Pantano, Linda Benincasa, Massimiliano Fabbiani, Giulia Piccini, Ilaria Rancan, Ginevra Giglioli, Valentina Abbiento, Emanuele Montomoli, Margherita Leonardi, Inesa Hyseni, Emanuele Andreano, Francesca Montagnani
Publikováno v:
Nature
The emergence of SARS-CoV-2 variants is jeopardizing the effectiveness of current vaccines and limiting the application of monoclonal antibody-based therapy for COVID-19 (refs. 1,2). Here we analysed the memory B cells of five naive and five convales
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077fbfff45495421108a42ff9c93471b
http://hdl.handle.net/11365/1182469
http://hdl.handle.net/11365/1182469
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Valentina Abbiento, Giada Antonelli, Piero Pileri, Noemi Manganaro, Elisa Pantano, Giuseppe Maccari, Silvia Marchese, Lorena Donnici, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Concetta De Santi, Massimiliano Fabbiani, Ilaria Rancan, Mario Tumbarello, Francesca Montagnani, Claudia Sala, Duccio Medini, Raffaele De Francesco, Emanuele Montomoli, Rino Rappuoli
Publikováno v:
Nature Communications. 14(1)
The continuous evolution of SARS-CoV-2 generated highly mutated variants able to escape natural and vaccine-induced primary immunity. The administration of a third mRNA vaccine dose induces a secondary response with increased protection. Here we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0357b46a90c9847639f79c0c45bffbb