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pro vyhledávání: '"Ginette Le Cam"'
Publikováno v:
Biochimica et biophysica acta. 1500(1)
The mdx mouse is an animal model for Duchenne muscular dystrophy (DMD), which is caused by the absence of dystrophin. Mdx limb muscles substantially compensate for the lack of dystrophin while the diaphragm is affected like DMD skeletal muscles. To u
Autor:
Valérie Rossi, Josiane Szpirer, Jean François Rouayrenc, Alphonse Le Cam, Göran Levan, Gilles Pagès, Ginette Le Cam, Claude Szpirer, Marcel Mariller
Publikováno v:
Gene. 94(2)
Three closely related SPI genes which encode highly homologous proteins of the serine protease inhibitor family secreted by rat liver (SPI-1, SPI-2 and SPI-3), were isolated from genomic libraries and sequenced, totally (SPI-2) or partially (SPI-1 an
Publikováno v:
European journal of biochemistry. 190(2)
Rat hepatocytes have the potential to secrete three similar acidic glycoproteins, serine protease inhibitors 1, 2 and 3 (SPI-1, SPI-2, SPI-3), recognized by the same antibodies. They were synthesized as precursors of comparable sizes (45 kDa), which
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 801:461-469
The effects of natural aliphatic polyamines on basal and hormone-stimulated protein phosphorylations in hepatocytes were studied. Cells isolated from adult rats were incubated in suspension with [ 32 P]orthophosphate, in the absence or presence of po
Publikováno v:
Journal of Cellular Physiology. 117:204-210
The effects of natural polyamines on cyclic AMP-mediated stimulation of amino acid transport in isolated rat hepatocytes were analyzed. Despite the fact that polyamines could directly compete with alpha-aminoisobutyric acid (AIB) for uptake, preincub
Autor:
Ginette Le Cam, Alphonse Le Cam, Patrick Auberger, Bernard Rossi, Gilles Pagès, Jean Olivier Contreres, Laurence Falquerho
Publikováno v:
Cell. 58(4)
Amino acid sequence of the precursor of the phosphorylated N-glycoprotein (pp63) secreted by rat hepatocytes was deduced from the cDNA sequence. This polypeptide (Mr = 40,586) was rich in both cysteine and proline and contained three potential N-glyc
Autor:
Alphonse Le Cam, Ginette Le Cam
Publikováno v:
FEBS letters. 210(1)
Synthesis of the growth hormone-regulated anti-protease GHR-P63 by rat hepatocytes was strongly reduced during acute inflammation. This decrease was detected 8 h after the onset of inflammation and reached a maximum after 24 h. A decrease in the GHR-
Publikováno v:
Biochimie. 67(10-11)
Resume Les effets de l'amiloride et les polyamines aliphatiques naturelles sur la phosphorylation des proteines hepatocytaires (basale et hormono-stimulee) ont ete caracterises. Les suspensions d'hepatocytes fraichement isoles de rat adulte ont ete i