Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice

Autor: Nai, Antonella ^*, Rubio, Aude ^*, Campanella, Alessandro, Gourbeyre, Ophélie, Artuso, Irene, Bordini, Jessica, Gineste, Aurélie, Latour, Chloé, Besson-Fournier, Céline, Lin, Herbert Y., Coppin, Hélène, Roth, Marie-Paule, Camaschella, Clara, Silvestri, Laura, Meynard, Delphine ^*

Publikováno v: In Blood 12 May 2016 127(19):2327-2336

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B Supplementary data

Autor: Besson-Fournier, Céline, Gineste, Aurélie, Latour, Chloé, Gourbeyre, Ophélie, Meynard, Delphine, Martin, Patricia, Oswald, Eric, Coppin, Hélène, Roth, Marie-Paule

Publikováno v: Blood
Blood, American Society of Hematology, 2016, 129 (4), [Epub ahead of print]. ⟨10.1182/blood-2016-10-748541⟩
Blood, American Society of Hematology, 2016, [Epub ahead of print]. ⟨10.1182/blood-2016-10-748541 ⟩
Blood, 2016, 129 (4), [Epub ahead of print]. ⟨10.1182/blood-2016-10-748541⟩

International audience; Activin B, which is strongly induced by inflammatory stimuli in the mouse liver, has recently appeared as a potent inductor of hepcidin in vitro, via the crossactivation of non-canonical SMAD1/5/8 signaling1,2. To confirm the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::047ca9afe2368e4d782662bdf77cf817
https://www.hal.inserm.fr/inserm-01430303

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