Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration.

Autor: Skovdahl HK; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Gopalakrishnan S; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Svendsen TD; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Granlund AVB; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Bakke I; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olav's University Hospital, Trondheim, Norway., Ginbot ZG; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Thorsvik S; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Department of Gastroenterology and Hepatology, Clinic of Medicine, St. Olav's University Hospital, Trondheim, Norway., Flatberg A; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Central Administration, St Olavs Hospital, The University Hospital in Trondheim, Trondheim, Norway., Sporsheim B; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Central Administration, St Olavs Hospital, The University Hospital in Trondheim, Trondheim, Norway., Ostrop J; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway., Mollnes TE; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Research Laboratory, Nordland Hospital, Bodø, Norway.; K.G. Jebsen Thrombosis Research and Expertise Centre, Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway.; Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway., Sandvik AK; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Centre of Molecular Inflammation Research (CEMIR), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Department of Gastroenterology and Hepatology, Clinic of Medicine, St. Olav's University Hospital, Trondheim, Norway., Bruland T; Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences, NTNU- Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Medicine, St. Olav's University Hospital, Trondheim, Norway.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2021 May 13; Vol. 12, pp. 679741. Date of Electronic Publication: 2021 May 13 (Print Publication: 2021).

Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease.

Autor: Sæterstad, Siri¹ (AUTHOR), Østvik, Ann Elisabet^1,2 (AUTHOR), Røyset, Elin Synnøve^1,3 (AUTHOR), Bakke, Ingunn^1,4 (AUTHOR), Sandvik, Arne Kristian^1,2,5 (AUTHOR), Granlund, Atle van Beelen^1,4,5 (AUTHOR) atle.granlund@ntnu.no

Publikováno v: PLoS ONE. 3/11/2022, Vol. 17 Issue 3, p1-23. 23p.

Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.

Autor: Gopalakrishnan, Shreya, Hansen, Marianne Doré, Skovdahl, Helene Kolstad, Roseth, Ingrid Aass, van Beelen Granlund, Atle, Østvik, Ann Elisabet, Bakke, Ingunn, Sandvik, Arne Kristian, Bruland, Torunn

Publikováno v: Frontiers in Immunology; 5/17/2022, Vol. 13, p1-15, 15p