Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ginam Park"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Molecular chaperones play an important part in protein folding and delivery in nature. Here, the authors report on the creation of a synthetic chaperone to control the folding of therapeutic peptides from random coil to alpha helix and demonstrate en
Externí odkaz:
https://doaj.org/article/42dca8adaa9e4ca9aa2c3c165a2016f1
Publikováno v:
Nature communications. 13(1)
Artificial, synthetic chaperones have attracted much attention in biomedical research due to their ability to control the folding of proteins and peptides. Here, we report bio-inspired multifunctional porous nanoparticles to modulate proper folding a
Highly efficient gene silencing and bioimaging based on fluorescent carbon dots in vitro and in vivo
Autor:
Seongchan Kim, Cheolhee Won, Ginam Park, Young-Joon Park, Younghoon Lee, Yuri Choi, Dal-Hee Min, Byeong Su Kim
Publikováno v:
Nano Research. 10:503-519
Small interfering RNA (siRNA) is an attractive therapeutic candidate for sequence-specific gene silencing to treat incurable diseases using small molecule drugs. However, its efficient intracellular delivery has remained a challenge. Here, we have de
Publikováno v:
Chemical Communications. 52:12112-12115
We present a new platform for multiplexed protein kinase activity assay using TiO2 decorated graphene oxide (GO), which is applicable to high throughput inhibitor screening. On the basis of the strong affinity of TiO2 for the phosphate group and the
Publikováno v:
Chemical communications (Cambridge, England). 51(78)
Graphene oxide quenches fluorescence corresponding to only a mismatched target due to selective denaturing of the thermo-unstable duplex composed of probe peptide nucleic acid and single base mismatched target RNA and thus, the fluorescence signal on
Publikováno v:
ChemInform. 45
Pd-nanoparticles deposited inside silica nanotubes efficiently catalyze cross coupling reactions of aryl halide (II) and thiazoles (IV) with arylboronic acids in water.
Publikováno v:
Green Chemistry. 15:3468
Silica nanotubes (SNTs) functionalized with Pd-NPs on the inner surface performed as efficient nano-reactors for C–C coupling in water; the nano-confinement offers minimized leaching of Pd and yet efficient mass transfer for Suzuki–Miyaura coupli