Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Gina Z. D'Amato"'
Autor:
Sebastian Bauer, Steven Attia, Hans Gelderblom, Peter Reichardt, Gina Z. D'Amato, Michael Heinrich, Julie Meade, Patrick Schöffski, Suzanne George, John Zalcberg, Margaret von Mehren, Jean-Yves Blay, Rodrigo Ruiz-Soto, Ping Chi, César Serrano, Robin L. Jones, Ying Su
Publikováno v:
Clinical Cancer Research, 27(23), 6333-6342. AMER ASSOC CANCER RESEARCH
Scientia
Scientia
Purpose: Most patients with gastrointestinal stromal tumor (GIST) have activating mutations in KIT/PDGFRA and are initially responsive to tyrosine kinase inhibitors (TKI). The acquisition of secondary mutations leads to refractory/relapsed disease. T
Autor:
Andrea P. Espejo, Jonathan C. Trent, Priscila Barreto-Coelho, Emily Jonczak, Junaid Arshad, Gina Z. D'Amato
Publikováno v:
J Immunother Precis Oncol
Background Leiomyosarcoma is a malignant mesenchymal tumor of cells of smooth muscle lineage arising commonly in retroperitoneum, uterus, large veins, and the limbs. The genetics of leiomyosarcomas are complex and there is very limited understanding
Autor:
Jonathan C. Trent, Andrew E. Rosenberg, Andrea P. Espejo-Freire, Andrew Elliott, Don S. Dizon, Margaret von Mehren, Ty K. Subhawong, Julio A. Diaz-Perez, Daniel Magee, Emily Jonczak, Junaid Arshad, William M. Korn, A. Hussein, Matthew J. Oberley, Priscila Barreto-Coelho, Philippos Apolinario Costa, Gina Z. D'Amato, Kirsten M. Leu, Moh’d M. Khushman
Publikováno v:
Cancers
Cancers; Volume 13; Issue 19; Pages: 4816
Cancers, Vol 13, Iss 4816, p 4816 (2021)
Cancers; Volume 13; Issue 19; Pages: 4816
Cancers, Vol 13, Iss 4816, p 4816 (2021)
Simple Summary Angiosarcomas (AS) are rare, highly aggressive sarcomas with limited therapeutic options. Genomic sequencing techniques have identified recurrent genetic abnormalities. Nevertheless, the association of these findings with etiology, sit
Autor:
Eduardo Edelman Saul, Andrea P. Espejo-Freire, Ty K. Subhawong, Jonathan C. Trent, Muhammad O. Hakim, Ahkeel Allen, Priscila Barreto-Coelho, Philippos Apolinario Costa, Staci J. Marbin, Gina Z. D'Amato, Bruna Menon Loureiro Apolinario Costa, Neha Goel
Publikováno v:
The breast journalREFERENCES. 27(10)
BACKGROUND Studies suggest that surgical breast augmentation with implants is a risk factor for breast desmoid tumors. The statistical strength of this correlation is unknown, as evidence is limited to anecdotal reports. METHODS Patients with breast
Autor:
Sant P. Chawla, Shreyaskumar Patel, Martee L. Hensley, George Wang, Roland Elmar Knoblauch, Arun S. Singh, Trilok V. Parekh, Daniel A. Rushing, Christopher W. Ryan, Robert G. Maki, Gina Z. D'Amato, Charles Forscher, Pamela E. Kaiser, Michael B. Livingston, Sharon Anne McCarthy, Damon R. Reed, George D. Demetri, John A. Charlson, Rahul Seth, Margaret von Mehren
Publikováno v:
Cancer
Background We performed a randomized phase 3 study of trabectedin versus dacarbazine in previously‐treated patients with liposarcoma/leiomyosarcoma (LPS/LMS). Methods Patients were randomized 2:1 to trabectedin (n = 384) or dacarbazine (n = 193) ad
Autor:
Philippos Apolinario Costa, Arshia Arora, Heng Tan, Yanelys Fernandez, Leticia Campoverde, Priscila Barreto Coelho, Steven Bialick, Andrea P. Espejo-Freire, Emily Jonczak, Gina Z. D'Amato, Ty Subhawong, Jonathan C. Trent
Publikováno v:
Journal of Clinical Oncology. 40:e23534-e23534
e23534 Background: Many systemic treatment options are described for desmoid tumors, including hormonal therapies, non-steroidal anti-inflammatory drugs, cytotoxic chemotherapeutic agents, and most recently, tyrosine kinase inhibitors. Although many
Autor:
Andrea P. Espejo-Freire, Leticia Campoverde, Yana Kropotova, Kurt Statz-Geary, Philippos Apolinario Costa, Priscila Barreto Coelho, Steven Bialick, Gina Z. D'Amato, Emily Jonczak, Jonathan C. Trent, Aditi Dhir
Publikováno v:
Journal of Clinical Oncology. 40:e23508-e23508
e23508 Background: Bone sarcomas account for about 5% of cancers in adolescents and young adults (AYA). Outcomes in this population are consistently inferior than children. It is poorly understood whether this is related to the tumor biology or the t
Autor:
Priscila Barreto Coelho, Steven Bialick, Brandon Edward Rose, Andrew Elliot, Phillip Walker, Jim Abraham, Kirsten Leu, Margaret von Mehren, Andrea P. Espejo-Freire, Philippos Apolinario Costa, Gina Z. D'Amato, Andrew Rosenberg, Jonathan C. Trent, Aditi Dhir
Publikováno v:
Journal of Clinical Oncology. 40:11580-11580
11580 Background: Synovial sarcomas (SS) harbor a specific, balanced, reciprocal translocation t(X;18) leading to the oncogenic SS18-SSX fusion. Defective DNA damage response (DDR) is a hallmark of cancer leading to genomic instability and is associa
Autor:
Steven Bialick, Kurt Statz-Geary, Andrew Elliott, Jim Abraham, Phillip Walker, Andrea P. Espejo-Freire, Priscila Barreto Coelho, Philippos Apolinario Costa, Kirsten Leu, Margaret von Mehren, Gina Z. D'Amato, Emily Jonczak, Jonathan C. Trent, Andrew Rosenberg, Aditi Dhir
Publikováno v:
Journal of Clinical Oncology. 40:11548-11548
11548 Background: Alterations in DNA damage response (DDR) pathways contribute to genomic instability and malignant progression and have been shown to be of clinical significance in several carcinomas and solid tumors. While some studies have identif
Autor:
Seiya Liu, Bernadette Miramontes, Felipe Ferreira Souza, Philippos Apolinario Costa, Ty Subhawong, Andrea P. Espejo-Freire, Emily Jonczak, Gina Z. D'Amato, Shree Venkat
Publikováno v:
Journal of Clinical Oncology. 40:e23543-e23543
e23543 Background: Desmoid tumors are locally invasive mesenchymal neoplasms of fibroblastic origin arising in deep soft tissue. Despite a rare incidence of 2.4-4.3 per one million and an inability to metastasize, desmoid tumors can cause significant