Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gina S, Gerwe"'
Autor:
Neil T. Fairweather, Bhavani Kasibhatla, Gina S. Gerwe, George E. Stake, Artem G. Evdokimov, Brian W. Howard, Jeffrey Lyle Gray, Matthew Pokross, Anny-Odile Colson, Sean R. Klopfenstein, Thomas R. Downs, Kevin G. Peters, Matthew B. Maier, Jeffrey J. Neuman, Julie A. Farmer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1574-1578
High-throughput screening of the P&GP corporate repository against several protein tyrosine phosphatases identified the sulfamic acid moiety as potential phosphotyrosine mimetic. Incorporation of the sulfamic acid onto a 1,2,3,4-tetrahydroisoquinolin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94deb8eb695847ffbb286bb5870663f2
https://doi.org/10.1016/j.bmcl.2005.12.051
https://doi.org/10.1016/j.bmcl.2005.12.051
Autor:
Kande K D, Amarasinghe, Artem G, Evdokimov, Artem G, Evidokimov, Kevin, Xu, Cynthia M, Clark, Matthew B, Maier, Anil, Srivastava, Anny-Odile, Colson, Gina S, Gerwe, George E, Stake, Brian W, Howard, Matthew E, Pokross, Jeffrey L, Gray, Kevin G, Peters
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(16)
The sulfamic acid phosphotyrosine mimetic was coupled with a previously known malonate template to obtain highly selective and potent inhibitors of HPTPbeta. Potentially hydrolyzable malonate ester functionalities were replaced with 1,2,4-oxadiazoles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c05f79a1a4e620626ea01c44e4375
https://pubmed.ncbi.nlm.nih.gov/16759857
https://pubmed.ncbi.nlm.nih.gov/16759857
Autor:
Anny-Odile Colson, Matthew B. Maier, Kande Amarasinghe, Anil K Srivastava, Kevin Xu, George E. Stake, Brian W. Howard, Cynthia Monesa Clark, Kevin G. Peters, Matthew Pokross, Artem G. Evdokimov, Gina S. Gerwe, Jeffrey Lyle Gray
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4745
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c90ea7c7aef51589e21c0b3e6a3308b2
https://doi.org/10.1016/j.bmcl.2006.08.077
https://doi.org/10.1016/j.bmcl.2006.08.077