Shining a Light on the Mechanisms of Sleep for Memory Consolidation

Autor: Rockelle S. Guthrie, Yesenia Cabrera, Michelle A. Frazer, Gina R. Poe

Publikováno v: Current Sleep Medicine Reports. 7:221-231

Purpose of review This paper reviews all optogenetic studies that directly test various sleep states, traits, and circuit-level activity profiles for the consolidation of different learning tasks. Recent findings Inhibiting or exciting neurons involv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::411037705dcfed41b7371aeacc700a21
https://doi.org/10.1007/s40675-021-00204-3

Unraveling why we sleep: Quantitative analysis reveals abrupt transition from neural reorganization to repair in early development

Autor: Van M. Savage, Geoffrey B. West, Alexander B. Herman, Junyu Cao, Gina R. Poe

Publikováno v: Science advances, vol 6, iss 38
Science Advances

Discovery of how sleep function shifts from neural reorganization to repair by combining mathematical theory and data analysis.
Sleep serves disparate functions, most notably neural repair, metabolite clearance and circuit reorganization. Yet th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc3a4a2a4bf62d440d3a475abb03654
https://escholarship.org/uc/item/635225xk

Sleep Changes Across the Female Hormonal Cycle Affecting Memory: Implications for Resilient Adaptation to Traumatic Experiences

Autor: Jasmine Holloway, Yesenia Cabrera, Gina R. Poe

Publikováno v: J Womens Health (Larchmt)

We review findings and propose a model explaining why women's adaptation to traumatic stress might be different than men's, including the role of cycling hormones and sleep differences in the development of post-traumatic stress and other stress-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483314906618e3e7a75775a38b14ca0d
https://europepmc.org/articles/PMC7097681/

Sex differences within sleep in gonadally intact rats

Autor: Gina R. Poe, Jasmine Holloway, Karina Keus, Yesenia Cabrera, Christy Gonzalez Echeverria, Kevin M. Swift, Brittany C. Clawson, Janelly Jimenez

Publikováno v: Sleep
Sleep, vol 43, iss 5

Sleep impacts diverse physiological and neural processes and is itself affected by the menstrual cycle; however, few studies have examined the effects of the estrous cycle on sleep in rodents. Studies of disease mechanisms in females therefore lack c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91080467feb8bda57fd431965873e79
https://doi.org/10.1093/sleep/zsz289

Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory

Autor: David Scott Bauer, Anthony E. Pickering, Michelle A. Frazer, Gary Aston-Jones, Elena M. Vazey, Yong Li, Susan J. Sara, Kyle J.D. Clark, Kevin M. Swift, Gina R. Poe, Brooks A. Gross

Publikováno v: Swift, K, Gross, B, Frazer, M, Bauer, D, Clark, K, Vazey, E, Aston-Jones, G, Li, Y, Pickering, A E, Sara, S & Poe, G 2018, ' Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory ', Current Biology, vol. 28, no. 22, pp. 3599-3609.e4 . https://doi.org/10.1016/j.cub.2018.09.054
Curr Biol

Summary Sleep is critical for proper memory consolidation. The locus coeruleus (LC) releases norepinephrine throughout the brain except when the LC falls silent throughout rapid eye movement (REM) sleep and prior to each non-REM (NREM) sleep spindle.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2991cf4eb328ac9423ddd0c568a03462
https://hdl.handle.net/1983/9eb62a6c-4876-45ae-b61e-daff641c8007