Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gina R Lewin"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Understanding the molecular mechanisms governing microbial interactions is crucial for unraveling the complexities of microbial communities and their ecological impacts. Here, we employed a two-species model system comprising the oral bacter
Externí odkaz:
https://doaj.org/article/2ccbfcdc3e1e42da92b45396eaa97d8b
Autor:
Adam J Book, Gina R Lewin, Bradon R McDonald, Taichi E Takasuka, Evelyn Wendt-Pienkowski, Drew T Doering, Steven Suh, Kenneth F Raffa, Brian G Fox, Cameron R Currie
Publikováno v:
PLoS Biology, Vol 14, Iss 6, p e1002475 (2016)
The evolution of cellulose degradation was a defining event in the history of life. Without efficient decomposition and recycling, dead plant biomass would quickly accumulate and become inaccessible to terrestrial food webs and the global carbon cycl
Externí odkaz:
https://doaj.org/article/e9e9a93e373a45c9982e76b202b1dea2
Autor:
Gina R Lewin, Amanda L Johnson, Rolando D Moreira Soto, Kailene Perry, Adam J Book, Heidi A Horn, Adrián A Pinto-Tomás, Cameron R Currie
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151840 (2016)
Deconstruction of the cellulose in plant cell walls is critical for carbon flow through ecosystems and for the production of sustainable cellulosic biofuels. Our understanding of cellulose deconstruction is largely limited to the study of microbes in
Externí odkaz:
https://doaj.org/article/58aa3bc24cca4a77a5e54b0787c45380
Autor:
Marc G. Chevrette, Caitlin M. Carlson, Humberto E. Ortega, Chris Thomas, Gene E. Ananiev, Kenneth J. Barns, Adam J. Book, Julian Cagnazzo, Camila Carlos, Will Flanigan, Kirk J. Grubbs, Heidi A. Horn, F. Michael Hoffmann, Jonathan L. Klassen, Jennifer J. Knack, Gina R. Lewin, Bradon R. McDonald, Laura Muller, Weilan G. P. Melo, Adrián A. Pinto-Tomás, Amber Schmitz, Evelyn Wendt-Pienkowski, Scott Wildman, Miao Zhao, Fan Zhang, Tim S. Bugni, David R. Andes, Monica T. Pupo, Cameron R. Currie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Host microbiomes are feasible sources for drug discovery. Here, using large-scale isolations, bioactivity assays and omics, the authors uncover the antimicrobial potential of insect-associated Streptomyces and identify a compound, cyphomycin, active
Externí odkaz:
https://doaj.org/article/854e622dbc4346adb3d1e484ca48f081
Autor:
Erin S. Gloag, Christopher W. Marshall, Daniel Snyder, Gina R. Lewin, Jacob S. Harris, Alfonso Santos-Lopez, Sarah B. Chaney, Marvin Whiteley, Vaughn S. Cooper, Daniel J. Wozniak
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Opportunistic pathogens establishing new infections experience strong selection to adapt, often favoring mutants that persist. Capturing this initial dynamic is critical for identifying the first adaptations that drive pathogenesis. Here we
Externí odkaz:
https://doaj.org/article/bb09f2057f05467fa4e687b97db7fb56
Autor:
Gina R. Lewin, Ananya Kapur, Daniel M. Cornforth, Rebecca P. Duncan, Frances L. Diggle, Dina A. Moustafa, Simone A. Harrison, Eric P. Skaar, Walter J. Chazin, Joanna B. Goldberg, Jennifer M. Bomberger, Marvin Whiteley
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Laboratory models are critical to basic and translational microbiology research. Models serve multiple purposes, from providing tractable systems to study cell biology to allowing the investigation of inaccessible clinical and environmental ecosystem
Autor:
John D. Perpich, Lan Yakoumatos, Kendall S. Stocke, Gina R. Lewin, Anayancy Ramos, Deborah R. Yoder-Himes, Marvin Whiteley, Richard J. Lamont
Publikováno v:
Infect Immun
Many pathogenic microbial ecosystems are polymicrobial, and community function can be shaped by interbacterial interactions. Little is known, however, regarding the genetic determinants required for fitness in heterotypic community environments. In p
Publikováno v:
mBio. 13(3)
The oral microbiota is enormously diverse, with over 700 microbial species identified across individuals that play a vital role in the health of our mouth and our overall well-being. In addition, as oral diseases such as caries (cavities) and periodo
Publikováno v:
Nat Rev Microbiol
Many microbial communities, including those involved in chronic human infections, are patterned at the micron scale. In this Review, we summarize recent work that has defined the spatial arrangement of microorganisms in infection and begun to demonst
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Most microbial knowledge comes from experiments in laboratory models, despite the assumption that these artificial systems alter microbial physiology relative the native environment. We tested this assumption for an oral pathogen, Porphy