Výsledky vyhledávání - "Gina M. Fadayel"

Improving newborn skin health: Effects of diaper care regimens on skin pH and erythema

Autor: Jennifer Gustin, Julie Ogle, Marty O. Visscher, Lisa Bohman, Andrew N. Carr, Vivek Narendran, Maria C. Mitchell, Gina M. Fadayel

Publikováno v: Pediatric Dermatology

Background/Objective Newborn infant skin is functional but immature, and diapering products can play a significant role in infant diapered skin health. Previous work demonstrated a regimen consisting of a diaper with an emollient and apertures on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b362011b42b9efaa5e20b98170b30d32
http://europepmc.org/articles/PMC8453578

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Use of an emollient‐containing diaper and pH‐buffered wipe regimen restores skin pH and reduces residual enzymatic activity

Autor: Julie Ogle, Vivek Narendran, Jennifer Gustin, Lisa Bohman, Andrew N. Carr, Lijuan Li, Maria C. Mitchell, Gina M. Fadayel, Tanuja Chaudhary, Marty O. Visscher

Publikováno v: Pediatric Dermatology

Background/Objectives Diaper dermatitis is one of the most frequent skin conditions affecting infants and is associated with elevated skin pH, exposure to urine and feces, and increased fecal protease and lipase activity, resulting in stratum corneum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbda661052df7fa365329c29ae4a0891
http://europepmc.org/articles/PMC7496339

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Effects of petrolatum, a petrolatum depositing body wash and a regular body wash on biomarkers and biophysical properties of the stratum corneum

Autor: Ching Stella, Gina M. Fadayel, Jeremy Christman, Karl Shiqing Wei, Rohan Lalith Wimalasena, R. Randall Wickett, Kenneth R. Wehmeyer, Russell Spruell, Amy Altemeier

Publikováno v: International journal of cosmetic scienceReferences. 43(2)

An important trend in the personal care industry involves the development of body wash products that not only clean the skin without damage but deposit conditioning ingredients to improve skin barrier function.The objective of this study was to devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f1e3ded60f949fdc4c74330f334c28
https://pubmed.ncbi.nlm.nih.gov/33336384

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Effects of season stratum corneum barrier function and skin biomarkers

Autor: Karl Shiqing, Wei, Ching, Stella, Kenneth R, Wehmeyer, Jeremy, Christman, Amy, Altemeier, Russell, Spruell, Rohan L, Wimalasena, Gina M, Fadayel, Raymond A, Reilman, Safa, Motlagh, Peter J, Stoffolano, Kathleen, Benzing, R Randall, Wickett

Publikováno v: Journal of cosmetic science. 67(3)

The skin on the lower legs of 25 female subjects was evaluated first in the winter, and then again in the summer of the same subjects. Barrier function was determined by measuring transepidermal water loss (TEWL), and skin hydration and dryness were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d9cd5a4fc00765797cfc7b1819ab7683
https://pubmed.ncbi.nlm.nih.gov/29394019

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Epidermal changes associated with symptomatic resolution of dandruff: biomarkers of scalp health

Autor: Gina M. Fadayel, Trevor John Darcy, Kathy M. Kerr, James Patrick Henry, Rohan Lalith Wimalasena, James Robert Schwartz, Haruko Mizoguchi, Stephen Morrall, Kevin John Mills, Thomas G. Filloon

Publikováno v: International Journal of Dermatology. 50:102-113

Background Dandruff is a common scalp condition characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect underlying histopathologic and biochemical events that must be reversed if treatment is to be effective. Objectives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::221c680cc8842c36a039778b704679de
https://doi.org/10.1111/j.1365-4632.2010.04629.x

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Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers

Autor: Michelle Hare, Jackson Christopher M, Bin Fang, Gina M. Fadayel, Richard Hedges, Michael Murawsky, Benjamin E. Blass, Jim Sheffer, Laurent Djandjighian, Ronald Eugene White, Andrew J. Fluxe, John Michael Janusz, Shengde Wu

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 16:6213-6218

A novel class of tetrazole-derived Kv1.5 blockers is disclosed. In in vitro studies, several compounds had IC50s ranging from 180 to 550 nM. In vivo studies indicated that compounds 2f and 2j increased right atrial ERP about 40% without affecting ven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23ce66fd7f547364b8f2a57760b9d64
https://doi.org/10.1016/j.bmcl.2006.09.021

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Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist

Autor: Salituro Francesco G, Vicki L. Taylor, Barry W. Siegel, Bruce M. Baron, John H. Kehne, Yaw Senyah, Harrison Boyd L, H.Steven White, Paul L.M. Van Giersbergen, Phillip L. Nyce, Christopher J. Schmidt, Michael Murawsky, Gina M. Fadayel, Timothy C. McCloskey

Publikováno v: European Journal of Pharmacology. 323:181-192

MDL 105,519, ( E )-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1 H -indole-2-carboxylic acid, is a potent and selective inhibitor of [ 3 H]glycine binding to the NMDA receptor. MDL 105,519 inhibits NMDA ( N -methyl- d -aspartate)-dependent responses i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea8d87937b04bbd1e28a1154c486add
https://doi.org/10.1016/s0014-2999(97)00045-9

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The 5-HT2 receptor antagonist, MDL 28,133A, disrupts the serotonergic-dopaminergic interaction mediating the neurochemical effects of 3,4-methylenedioxymethamphetamine

Autor: Sorensen Stephen M, Thaddeus R. Nieduzak, Christine K. Black, Teresa M. Humphreys, Gina M. Fadayel, Christopher J. Schmidt, Vicki L. Taylor

Publikováno v: European Journal of Pharmacology. 220:151-159

The selective 5-HT2 receptor antagonist MDL 28,133A dose dependently blocked the long-term deficits in rat brain 5-HT concentrations produced by the substituted amphetamine analogue 3,4-methylenedioxymethamphctamine (MDMA). This protective effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbf17dbbe96f4a5da47dc4c79538818
https://doi.org/10.1016/0014-2999(92)90743-n

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