Výsledky vyhledávání - "Gina M. Conenello"

Akademický článek

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence.

Autor: Gina M Conenello, Dmitriy Zamarin, Lucy A Perrone, Terrence Tumpey, Peter Palese

Publikováno v: PLoS Pathogens, Vol 3, Iss 10, Pp 1414-1421 (2007)

The proapoptotic PB1-F2 protein of influenza A viruses has been shown to contribute to pathogenesis in the mouse model. Expression of full-length PB1-F2 increases the pathogenesis of the influenza A virus, causing weight loss, slower viral clearance,

Externí odkaz: https://doaj.org/article/affef57df361443fa534972cbb953456

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A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

Autor: Elizabeth Rosenzweig, Peter Palese, Zsuzsanna T. Varga, Jennifer R. Tisoncik, Gina M. Conenello, Michael G. Katze

Publikováno v: Journal of Virology. 85:652-662

The PB1-F2 protein of influenza A virus can contribute to viral pathogenesis of influenza virus strains. Of note, an N66S amino acid mutation in PB1-F2 has been shown to increase the pathogenesis associated with H5N1 Hong Kong/1997 and H1N1 Brevig Mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54073b282661f13e4983b548a7e76f86
https://doi.org/10.1128/jvi.01987-10

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Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

Autor: Jörn Dengjel, Dorothee Dormann, Till Strowig, Gina M. Conenello, Monica Lee, Christian Münz, Patrick C. Rämer, Marc Pypaert, Monique Gannagé, Frida Arrey, Randy A. Albrecht, Adolfo García-Sastre, Tania Torossi, Jens S. Andersen

Publikováno v: Gannagé, M, Dormann, D, Albrecht, R, Dengjel, J, Torossi, T, Rämer, P C, Lee, M, Strowig, T, Arrey, F, Conenello, G, Pypaert, M, Andersen, J, García-Sastre, A & Münz, C 2009, ' Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes ', Cell Host & Microbe, vol. 6, no. 4, pp. 367-380 . https://doi.org/10.1016/j.chom.2009.09.005
Cell host & microbe
Europe PubMed Central

Udgivelsesdato: 2009-Oct-22 Influenza A virus is an important human pathogen causing significant morbidity and mortality every year and threatening the human population with epidemics and pandemics. Therefore, it is important to understand the biolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4a300b34d18ea97e4914c937e8a30e

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Effective replication of human influenza viruses in mice lacking a major α2,6 sialyltransferase

Autor: Peter Palese, James C. Paulson, Gina M. Conenello, Laurel Glaser

Publikováno v: Virus Research. 126:9-18

The hemagglutinins of influenza viruses isolated from humans typically prefer binding to sialic acid in an alpha2,6 linkage. Presumably, the virus uses the presence of these receptors on the respiratory tract to gain entrance into the host cell. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8fe44663f8202054e1650febf6cdc8
https://doi.org/10.1016/j.virusres.2007.01.011

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A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

Autor: Lucy A. Perrone, Peter Palese, Terrence M. Tumpey, Dmitriy Zamarin, Gina M. Conenello

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 3, Iss 10, Pp 1414-1421 (2007)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e613b5893ef58ac57d2c1f12c6305d78
https://pubmed.ncbi.nlm.nih.gov/17922571

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