Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gina M Scurti"'
Autor:
Long Chen, David F Stroncek, Gang Zeng, Steven Highfill, Robert Reger, Stefan Barisic, Elena Cherkasova, Elizabeth M Brahmbhatt, Timothy T Spear, Ujjawal Savani, Stephanie Pierre, Gina M Scurti, Muna Igboko, Rosa Nadal, Gordon Parry, Annika V Dalheim, Michael I Nishimura, Richard W Childs
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background We discovered a novel human endogenous retrovirus (CT-RCC HERV-E) that was selectively expressed in most clear cell renal cell carcinomas (ccRCC) and served as a source of antigens for T cell-mediated killing. Here, we described the clonin
Externí odkaz:
https://doaj.org/article/bdd7b926eb5a41dab026790fbcaa4b31
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Adoptive T cell therapy with T cell receptor (TCR)-modified T cells has shown promise in treating metastatic melanoma and other malignancies. However, studies are needed to improve the efficacy and durability of responses of TCR-modified T c
Externí odkaz:
https://doaj.org/article/0d6455e91542435a9f8f3cd3c71292a6
Autor:
Tamson V. Moore, Gina M. Scurti, Matthew DeJong, Siao-Yi Wang, Annika V. Dalheim, Courtney R. Wagner, Kelli A. Hutchens, Jodi J. Speiser, Constantine V. Godellas, Chris Fountain, Jessica Fleser, Tarsem Moudgil, Mallory Thomas, David Murray, Brendan D. Curti, Joseph I. Clark, Bernard A. Fox, Michael I. Nishimura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 352-363 (2021)
T cells that are gene-modified with tumor-specific T cell receptors are a promising treatment for metastatic melanoma patients. In a clinical trial, we treated seven metastatic melanoma patients with autologous T cells transduced to express a tyrosin
Externí odkaz:
https://doaj.org/article/89a5e7e4a04a46e287fbf116f56ea560
Autor:
Suzanne Quinn, Natasha Lenart, Victoria Dronzek, Gina M. Scurti, Nasheed M. Hossain, Michael I. Nishimura
Publikováno v:
Vaccines, Vol 10, Iss 3, p 457 (2022)
Immunotherapy is a beneficial treatment approach for multiple cancers, however, current therapies are effective only in a small subset of patients. Adoptive cell transfer (ACT) is a facet of immunotherapy where T cells targeting the tumor cells are t
Externí odkaz:
https://doaj.org/article/a143d7add8e7460fbf251ae60183ed45
Autor:
Estefania Gauto-Mariotti, Amanda J. Nguyen, Chloe Waters, Gina M. Scurti, Sandra Haddad, Milind M. Velankar, Annika V. Dalheim, Victoria Dronzek, Rhett P. Ketterling, Michael I. Nishimura, Joanna C. Dalland, Nasheed M. Hossain
Publikováno v:
Journal of Hematopathology. 15:229-237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1767ee53e821871154f3811f6635f645
https://doi.org/10.1007/s12308-022-00519-2
https://doi.org/10.1007/s12308-022-00519-2
Autor:
Aleksandra Vuchkovska, David G. Glanville, Gina M. Scurti, Michael I. Nishimura, Paula White, Andrew T. Ulijasz, Makio Iwashima
Publikováno v:
ImmunologyREFERENCES. 166(2)
Sialic acid-binding immunoglobulin-type lectins (Siglecs) are a family of immunoglobulin-type lectins that mediate protein-carbohydrate interactions via sialic acids attached to glycoproteins or glycolipids. Most of the CD33-related Siglecs (CD33rSig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b02aedb66e671820e1b97c8d9b3848
https://pubmed.ncbi.nlm.nih.gov/35290663
https://pubmed.ncbi.nlm.nih.gov/35290663
Adoptive T cell therapy with T cell receptor (TCR)-modified T cells has shown promise in treating metastatic melanoma and other malignancies. However, studies are needed to improve the efficacy and durability of responses of TCR-modified T cells. Sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efde6a44e09348f535ef99bdddd07b8e
https://doi.org/10.21203/rs.3.rs-238261/v1
https://doi.org/10.21203/rs.3.rs-238261/v1
Autor:
Timothy T Spear, Timothy Riley, Kendra C Foley, David C Murray, Patricia E Simms, Gina M Scurti, Yuan Wang, Lance M Hellman, Rachel H McMahan, Hugo R Rosen, Brian M Baker, Michael I Nishimura
Publikováno v:
The Journal of Immunology. 196:214.15-214.15
A major obstacle hindering the development of effective immunity against viral infections, their associated disease, and certain cancers is their genomic instability. Accumulation of mutations can alter processing/presentation of antigens recognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af546171cf81167f70b79477be9cdd9d
https://doi.org/10.4049/jimmunol.196.supp.214.15
https://doi.org/10.4049/jimmunol.196.supp.214.15
Autor:
Stefan Barisic, Elena Cherkasova, Rosa Nadal, Xin Tian, Long Chen, Angelina Parrizzi, Robert N. Reger, Gina M. Scurti, Michael I. Nishimura, Richard W. Childs
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101324- (2024)
In vivo expansion of genetically modified T cells in cancer patients following adoptive transfer has been linked to both anti-tumor activity and T cell-mediated toxicities. The development of digital PCR has improved the accuracy in quantifying the i
Externí odkaz:
https://doaj.org/article/5b592d3693804319b37fe4a8cf5d58bf