Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gina M Clayton"'
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0213052 (2019)
Lipocalins represent the most important protein family of the mammalian respiratory allergens. Four of the seven named dog allergens are lipocalins: Can f 1, Can f 2, Can f 4, and Can f 6. We present the structure of Can f 6 along with data on the bi
Externí odkaz:
https://doaj.org/article/212073fee6444221849050dc236f5742
Lipocalins represent the most important protein family of the mammalian respiratory allergens. Four of the seven named dog allergens are lipocalins: Can f 1, Can f 2, Can f 4, and Can f 6. We present the structure of Can f 6 along with data on the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2654af285a35c0e26233dc6ed834d4d7
https://doi.org/10.1101/551549
https://doi.org/10.1101/551549
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0213052 (2019)
PLoS ONE
PLoS ONE
Lipocalins represent the most important protein family of the mammalian respiratory allergens. Four of the seven named dog allergens are lipocalins: Can f 1, Can f 2, Can f 4, and Can f 6. We present the structure of Can f 6 along with data on the bi
Autor:
R. Michael Garavito, Gina M. Clayton, Kebreab Ghebreselasie, Lawrence J. Marnett, Daniel J. Hermanson, Surajit Banerjee, Shu Xu
Publikováno v:
Journal of Biological Chemistry. 289:6799-6808
Oxicams are widely used nonsteroidal anti-inflammatory drugs (NSAIDs), but little is known about the molecular basis of the interaction with their target enzymes, the cyclooxygenases (COX). Isoxicam is a nonselective inhibitor of COX-1 and COX-2 wher
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB183
Autor:
Keith W. Rickert, Kevin J. Lumb, Stephen M. Soisson, Sujata Sharma, Sangita B. Patel, Joan Zugay-Murphy, Lynn Miesel, Gina M. Clayton, Sheo B. Singh, Maria Kornienko, Srivanya Tummala, Daniel J. Klein, John C. Reid
Publikováno v:
Journal of Biological Chemistry. 288:34073-34080
The emergence of antibiotic-resistant strains of pathogenic bacteria is an increasing threat to global health that underscores an urgent need for an expanded antibacterial armamentarium. Gram-negative bacteria, such as Escherichia coli, have become i
Autor:
Michael T. Falta, Yang Wang, Andrew P. Fontenot, Gina M. Clayton, Shaodong Dai, Frances Crawford, Brian T. Wimberly, Andrey Novikov, Natalie A. Bowerman, Philippa Marrack, Jeffrey S. Kieft, John W. Kappler
T-cell-mediated hypersensitivity to metal cations is common in humans. How the T cell antigen receptor (TCR) recognizes these cations bound to a major histocompatibility complex (MHC) protein and self-peptide is unknown. Individuals carrying the MHCI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64382c5a2a2501b7bdcb012e9d31ddb1
https://europepmc.org/articles/PMC4269484/
https://europepmc.org/articles/PMC4269484/
Autor:
Philippa Marrack, John W. Kappler, Andrew P. Fontenot, Radleigh G. Santos, Alex N. Tinega, Frances Crawford, Michael T. Falta, Gina M. Clayton, Yuxiao Wang, Xuewu Zhang, Marc A. Giulianotti, Lisa A. Maier, Clemencia Pinilla, Douglas G. Mack
Publikováno v:
The Journal of Experimental Medicine
Identification of peptides that form complexes with beryllium and class II HLA molecules and are recognized by CD4+ T cells from patients with chronic beryllium disease.
Chronic beryllium disease (CBD) is a granulomatous disorder characterized b
Chronic beryllium disease (CBD) is a granulomatous disorder characterized b
Autor:
Philippa Marrack, Gina M. Clayton, John W. Kappler, Yang Wang, Shaodong Dai, Wei Gao, Lei Yin
T cell recognition of foreign peptide antigen and tolerance to self peptides is key to the proper function of the immune system. Usually, in the thymus T cells that recognize self MHC + self peptides are deleted and those with the potential to recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bc8061849e2750f57fa98465b538b3
https://europepmc.org/articles/PMC3951410/
https://europepmc.org/articles/PMC3951410/
Publikováno v:
Journal of structural biology. 167(3)
We have recently reported the X-ray structure of the cyclic nucleotide regulated potassium channel, MlotiK1. Here we describe the application of both electron and X-ray crystallography to obtain high quality crystals. We suggest that the combined app