Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Gina M, Calabrese"'
Autor:
Basel M. Al-Barghouthi, Larry D. Mesner, Gina M. Calabrese, Daniel Brooks, Steven M. Tommasini, Mary L. Bouxsein, Mark C. Horowitz, Clifford J. Rosen, Kevin Nguyen, Samuel Haddox, Emily A. Farber, Suna Onengut-Gumuscu, Daniel Pomp, Charles R. Farber
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Osteoporosis GWAS faces two challenges, causal gene discovery and a lack of phenotypic diversity. Here, the authors use the Diversity Outbred mouse population to inform human GWAS using networks and map genetic loci for 55 bone traits, identifying ne
Externí odkaz:
https://doaj.org/article/4e2ac2ef78f74d52bdfce93123908f3a
Autor:
Gina M. Calabrese, Karin S. Pfennig
Publikováno v:
Biology letters. 18(11)
Mating with another species is often maladaptive because it generally results in no or low-fitness offspring. When hybridization is sufficiently costly, individuals should avoid mating with heterospecifics even if it reduces their ability to mate wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3862b9624ff0563ab42bcad4affaf0ee
https://pubmed.ncbi.nlm.nih.gov/36382373
https://pubmed.ncbi.nlm.nih.gov/36382373
Autor:
Madison L Doolittle, Gina M Calabrese, Larry D Mesner, Dana A Godfrey, Robert D Maynard, Cheryl L Ackert-Bicknell, Charles R Farber
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008805 (2020)
Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last decade, genome-wide association studies (GWASs) have identified over 1000 associations for
Externí odkaz:
https://doaj.org/article/ba9084e0cc5e4ca1b66b6852a2ebf052
Autor:
Larry D Mesner, Gina M Calabrese, Basel Al-Barghouthi, Daniel M Gatti, John P Sundberg, Gary A Churchill, Dana A Godfrey, Cheryl L Ackert-Bicknell, Charles R Farber
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008123 (2019)
Bone mineral density (BMD) is a strong predictor of osteoporotic fracture. It is also one of the most heritable disease-associated quantitative traits. As a result, there has been considerable effort focused on dissecting its genetic basis. Here, we
Externí odkaz:
https://doaj.org/article/13e9e6a3b62342489aebf5f6fe8010c7
Autor:
Gina M. Calabrese, Karin S. Pfennig
Publikováno v:
The American naturalist. 201(1)
Climate change is altering species' habitats, phenology, and behavior. Although sexual behaviors impact population persistence and fitness, climate change's effects on sexual signals are understudied. Climate change can directly alter temperature-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713c69af746dd6d7b0339224a7855dc8
https://pubmed.ncbi.nlm.nih.gov/36524933
https://pubmed.ncbi.nlm.nih.gov/36524933
Autor:
Luke J Dillard, Will T Rosenow, Gina M Calabrese, Larry D Mesner, Basel M Al-Barghouthi, Abdullah Abood, Emily A Farber, Suna Onengut-Gumuscu, Steven M Tommasini, Mark A Horowitz, Clifford J Rosen, Lutian Yao, Ling Qin, Charles R Farber
Genome-wide association studies (GWASs) have revolutionized our understanding of the genetics of complex diseases, such as osteoporosis; however, the challenge has been converting associations to causal genes. Studies have demonstrated the utility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd743a09b7043b2445d1f5ef66219c2
https://doi.org/10.1101/2022.12.13.520148
https://doi.org/10.1101/2022.12.13.520148
Autor:
Karin S. Pfennig, Gina M Calabrese
Publikováno v:
Behavioral Ecology. 32:1183-1191
New species can arise when female preferences and male sexual signals diverge across populations and thereby reduce mating between populations. Under this hypothesized mechanism for speciation, mate preferences and sexual signals should be correlated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da58ea9bdb8e9427b0abfd8aa7a20eb
https://doi.org/10.1093/beheco/arab082
https://doi.org/10.1093/beheco/arab082
Autor:
Meghan M. Moran, Frank C. Ko, Larry D. Mesner, Gina M. Calabrese, Basel M. Al-Barghouthi, Charles R. Farber, D. Rick Sumner
Publikováno v:
Bone
There are over one million cases of failed bone repair in the U.S. annually, resulting in substantial patient morbidity and societal costs. Multiple candidate genes affecting bone traits such as bone mineral density have been identified in human subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc988c3fbb6d3fe8802d7a53951bb59
https://doi.org/10.2139/ssrn.4117253
https://doi.org/10.2139/ssrn.4117253
Autor:
Jinho Heo, Will T. Rosenow, Virginia L. Ferguson, Kang-Ping Du, David L. Brautigan, Robert D. Maynard, Louis C. Gerstenfeld, Larry D. Mesner, Elise F. Morgan, Bhavya Senwar, Gina M. Calabrese, Charles R. Farber, Aaron Nakasone, Cheryl L. Ackert-Bicknell, Basel M. Al-Barghouthi
Genome-wide association studies (GWASs) for bone mineral density (BMD) have identified over 1,100 associations to date. However, identifying causal genes implicated by such studies has been challenging. Recent advances in the development of transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7a18f51c003bcd5283211eb1fb6404
https://doi.org/10.1101/2021.10.12.464046
https://doi.org/10.1101/2021.10.12.464046
Autor:
Karin S. Pfennig, Gina M Calabrese
Publikováno v:
Journal of Heredity. 111:138-146
Adaptive radiations are characterized by the rapid proliferation of species. Explaining how adaptive radiations occur therefore depends, in part, on identifying how populations become reproductively isolated—and ultimately become different species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e393bda7af4130d89b16b1c7ba2d5ee
https://doi.org/10.1093/jhered/esz073
https://doi.org/10.1093/jhered/esz073